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Biomedical and Life Sciences

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  1. Laboratory bench scaling was done and an average of 1.85 fold increase by Response Surface Methodology (RSM) optimization was obtained. It was found that the predicted value (4.96 IU/ml) obtained by RSM is in ...

    Authors: Tanveer Pirzadah, Shashank Garg, Joginder Singh, Ashish Vyas, Manish Kumar, Naseem Gaur, Madhu Bala, Reiaz Rehman, Ajit Varma, Vivek Kumar and Manoj Kumar
    Citation: SpringerPlus 2014 3:622
  2. Weissellicin L, a novel bacteriocin produced by Weissella hellenica 4 7, was previously characterized but its full amino acid sequence remain unknown. The draft genome sequencing analysis of Weissella hellenica ...

    Authors: Yi-sheng Chen, Yun-shien Lee, Hui-chung Wu, Chih-ming Chiang, Shwu-fen Pan and Kun-hon Leong
    Citation: SpringerPlus 2014 3:617
  3. The Colletotrichum gloeosporioides species complex is among the most destructive fungal plant pathogens in the world, however, identification of isolates of quarantine importance to the intra-specific level is co...

    Authors: Sephra N Rampersad, Fazeeda N Hosein and Christine VF Carrington
    Citation: SpringerPlus 2014 3:614
  4. cDNA-AFLP methodology was used to gain insight into gene fragments differentially present in the mRNA profiles of Quercus suber roots infected with zoospores of Phytophthora cinnamomi at different post challenge ...

    Authors: Ghazal Ebadzad and Alfredo Cravador
    Citation: SpringerPlus 2014 3:613
  5. Endurance performance decreases during ageing due to alterations in physiological characteristics, energy stores, and psychological factors. To investigate alterations in physiological characteristics and body...

    Authors: Sandro Manuel Mueller, Beat Knechtle, Patrizia Knechtle and Marco Toigo
    Citation: SpringerPlus 2014 3:608
  6. To investigated whether an acute hypoxic stimulus affects muscle strength development assessed by isokinetic dynamometry during maximal knee extension. A total of 15 healthy young men participated in this stud...

    Authors: Rafael Kenji Ivamoto, Fernanda Patti Nakamoto, Rodrigo Luiz Vancini, Ana Amélia Benedito-Silva, Claudio Andre Barbosa de Lira and Marília dos Santos Andrade
    Citation: SpringerPlus 2014 3:604
  7. The Trichoderma genus consists of a group of free-living filamentous fungi, including species able to act as biological control agents (BCAs) against pathogenic fungi. It is believed that this ability is due to s...

    Authors: João PC Brito, Marcelo HS Ramada, Mariana TQ de Magalhães, Luciano P Silva and Cirano J Ulhoa
    Citation: SpringerPlus 2014 3:600
  8. The association between MUC1 polymorphism rs4072037 and the risk of gastric cancer has been described in several studies. However, these studies yielded inconsistent results, especially in different pathological ...

    Authors: Xinyang Liu, Zhichao Wang, Xiaowei Zhang, Jinjia Chang, Wenbo Tang, Lu Gan, Zheng Wu and Jin Li
    Citation: SpringerPlus 2014 3:599
  9. Feeder cells are essential for the establishment and culture of pluripotent rat embryonic stem cells (ESC) in vitro. Therefore, we tested several fibroblast and epithelial cell lines derived from the female genit...

    Authors: Nils-Holger Zschemisch, Regina Eisenblätter, Cornelia Rudolph, Silke Glage and Martina Dorsch
    Citation: SpringerPlus 2014 3:588
  10. Private insurance plays a minor role in paying for pharmaceuticals in New Zealand, despite controversy about access through the public health system. The present study examines New Zealand consumers’ perceptio...

    Authors: Rajan Ragupathy, Zaheer-ud-Din Babar, Wasif Mirza, Mitali Daiya, Himesh Chandra, Ali Yousif and Maninder Girn
    Citation: SpringerPlus 2014 3:587
  11. The prevention of muscle wasting is important for maintaining quality of life, since loss of muscle mass can lead to a bedridden state and decreased resistance to diseases. The prevention of muscle wasting req...

    Authors: Tomonori Sato, Yoshiaki Ito and Takashi Nagasawa
    Citation: SpringerPlus 2014 3:584
  12. We report the screening and characterization of EPS produced by LAB identified as Leuconostoc kimchii isolated from pulque, a traditional Mexican fermented, non-distilled alcoholic beverage produced by the fermen...

    Authors: Ingrid Torres-Rodríguez, María Elena Rodríguez-Alegría, Alfonso Miranda-Molina, Martha Giles-Gómez, Rodrigo Conca Morales, Agustín López-Munguía, Francisco Bolívar and Adelfo Escalante
    Citation: SpringerPlus 2014 3:583
  13. Agave tequilana is an angiosperm species that belongs to the family Asparagaceae (formerly Agavaceae). Even though there is information regarding to some aspects related to the megagametogenesis of A. tequilana, ...

    Authors: Alejandra G González-Gutiérrez, Antonia Gutiérrez-Mora and Benjamín Rodríguez-Garay
    Citation: SpringerPlus 2014 3:575
  14. The plant pathogenic fungus, Sphaeropsis visci a dark-spored species of Botryosphaeriaceae, which causes the leaf spot disease of the European mistletoe (Viscum album). This species seems to have potential as a t...

    Authors: Ildikó Varga, Péter Poczai, István Cernák and Jaakko Hyvönen
    Citation: SpringerPlus 2014 3:569
  15. Plant microRNAs (miRNAs) play essential roles in the post-transcriptional regulation of gene expression during development, flowering, plant growth, metabolism, and stress responses. Verticillium wilt is one o...

    Authors: Xiaohong He, Quan Sun, Huaizhong Jiang, Xiaoyan Zhu, Jianchuan Mo, Lu Long, Liuxin Xiang, Yongfang Xie, Yuzhen Shi, Youlu Yuan and Yingfan Cai
    Citation: SpringerPlus 2014 3:564
  16. Brain ischemia leads to a decrease in pHo. We have shown previously in synaptosomes that the extracellular acidification induces depolarization of mitochondria followed by synthesis of superoxide anions and oxida...

    Authors: Tatyana G. Pekun, Sviatlana V. Hrynevich, Tatyana V. Waseem and Sergei V. Fedorovich
    Citation: SpringerPlus 2014 3:560
  17. We previously demonstrated that blocking the hepatocyte growth factor (HGF) receptor, c-Met, using a HGF antagonist, NK4, inhibited arthritis in a rheumatoid arthritis (RA) model mice. In the present study, we...

    Authors: Seiji Shibasaki, Sachi Tsunemi, Sachie Kitano, Masahiro Sekiguchi, Hajime Sano and Tsuyoshi Iwasaki
    Citation: SpringerPlus 2014 3:554
  18. α-Tocopherol (α-T) and α-tocotrienol (α-T3) are well recognized as lipophilic antioxidants. Nevertheless, there is limited knowledge on their location in heterogeneous cell membranes. We first investigated the...

    Authors: Toshiyuki Nakamura, Ayako Noma and Junji Terao
    Citation: SpringerPlus 2014 3:550
  19. Linear Mixed models (LMMs) that incorporate genetic and spatial covariance structures have been used for many years to estimate genetic parameters and to predict breeding values in animal and plant breeding. A...

    Authors: Nihal H. De Silva, Luis Gea and Russell Lowe
    Citation: SpringerPlus 2014 3:547
  20. Single Nucleotide Polymorphism (SNP) markers were used in characterization of 113 cowpea accessions comprising of 108 from Ghana and 5 from abroad. Leaf tissues from plants cultivated at the University of Ghan...

    Authors: Kenneth F. Egbadzor, Kwadwo Ofori, Martin Yeboah, Lawrence M. Aboagye, Michael O. Opoku-Agyeman, Eric Y. Danquah and Samuel K. Offei
    Citation: SpringerPlus 2014 3:541
  21. Seven isoforms of Broad-Complex (PhBR-C), in which the sequence of the zinc finger domain differed (referred to as Z1, Z2, Z3, Z2/Z3, Z4, Z5/Z6, and Z6, respectively), were cloned from the yellow-spotted longicor...

    Authors: Keisuke Nagamine, Takumi Kayukawa, Sugihiko Hoshizaki, Takashi Matsuo, Tetsuro Shinoda and Yukio Ishikawa
    Citation: SpringerPlus 2014 3:539
  22. The purpose of this study was (i) to determine the age of peak triathlon performance for world class athletes competing in Olympic, Half-Ironman and Ironman distance races and (ii) to investigate a potential chan...

    Authors: Raphael Knechtle, Christoph Alexander Rüst, Thomas Rosemann and Beat Knechtle
    Citation: SpringerPlus 2014 3:538
  23. Trichoderma sp. SL2 has been previously reported to enhance rice germination, vigour, growth and physiological characteristics. The use of Potato Dextrose Agar as carrier of Trichoderma sp. SL2 inoculant is not p...

    Authors: Febri Doni, Anizan Isahak, Che Radziah Che Mohd Zain, Salwati Mohd Ariffin, Wan Nur’ashiqin Wan Mohamad and Wan Mohtar Wan Yusoff
    Citation: SpringerPlus 2014 3:532
  24. Free intracellular taurine and principal α-amino acids (glutamate, glutamine, aspartate, asparagine and alanine) are abundant in human heart. They are cellular regulators and their concentration can change in ...

    Authors: Martin Lewis, Ben Littlejohns, Hua Lin, Gianni D Angelini and M-Saadeh Suleiman
    Citation: SpringerPlus 2014 3:523
  25. Liver, heart and abdominal muscle samples from scalloped (Sphyrna lewini) and smooth (Sphyrna zygaena) hammerhead sharks were analysed to characterise their lipid and fatty acid profiles. Samples were compared bo...

    Authors: Bruce Clement Davidson, Wynand Nel, Afsha Rais, Vahid Namdarizandi, Scott Vizarra and Geremy Cliff
    Citation: SpringerPlus 2014 3:521
  26. The objective of this experiment was to study the effect of dietary supplementation of Coenzyme Q10 on broiler growth rate, carcass characteristics and cost of production. A biological trial was carried out wi...

    Authors: Marappan Gopi, Manika Ragavan Purushothaman and Dooraisamy Chandrasekaran
    Citation: SpringerPlus 2014 3:518
  27. The aim of the present study was to compare bioethanol production from wet exploded corn stover (WECS) and loblolly pine (WELP) hydrolyzed with in-house and commercial enzymes and fermented separately (SHF) an...

    Authors: Vandana Rana, Anahita D Eckard and Birgitte K Ahring
    Citation: SpringerPlus 2014 3:516
  28. Creatine plays an important role in the cell as an energy buffer. As the energy system is a basic element of the organism it may possibly contribute to differences between rainbow trout strains selected for th...

    Authors: Andreas Borchel, Marieke Verleih, Alexander Rebl, Carsten Kühn and Tom Goldammer
    Citation: SpringerPlus 2014 3:510
  29. Marine fungi represent a group of organisms extremely important from an ecological and biotechnological point of view, but often still neglected. In this work, an in-depth analysis on the systematic and the ph...

    Authors: Giorgio Gnavi, Enrico Ercole, Luigi Panno, Alfredo Vizzini and Giovanna C Varese
    Citation: SpringerPlus 2014 3:508
  30. The contamination of consumer food and animal feed with toxigenic fungi has resulted in economic losses worldwide in animal industries. Mycotoxins are highly biologically reactive secondary metabolites and can...

    Authors: Claudia Lautert, Laerte Ferreiro, Patrícia Wolkmer, Francine C Paim, Cássia B da Silva, Jeandre AS Jaques, Sônia TA Lopes and Janio M Santurio
    Citation: SpringerPlus 2014 3:506
  31. Brain-derived neurotrophic factor (BDNF) regulates multiple biological processes ranging from central nervous system development and function to neuroinflammation and myogenic differentiation and repair. While...

    Authors: Anmol Kumar, Kärt Varendi, Johan Peränen and Jaan-Olle Andressoo
    Citation: SpringerPlus 2014 3:502
  32. The enzymatic and acid hydrolysis have converted eight new starches into a range of chain lengths mainly including glucose, maltose, and maltodextrins as observed on TLC plates, irrespective to the starch vari...

    Authors: Ginette Doué, Micaël Bédikou, Gisèle Koua, Rose-Monde Mégnanou and Sébastien Niamké
    Citation: SpringerPlus 2014 3:498
  33. Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumour in humans and is highly resistant to current treatment modalities. We have explored the combined treatment of the endoplasmic reticul...

    Authors: Ingrid A M van Roosmalen, Carlos R Reis, Rita Setroikromo, Saravanan Yuvaraj, Justin V Joseph, Pieter G Tepper, Frank A E Kruyt and Wim J Quax
    Citation: SpringerPlus 2014 3:495

    The Erratum to this article has been published in SpringerPlus 2014 3:738

  34. Current databases of Phyllostachys pubescens full-length cDNAs (FL-cDNAs) provide a rich source of sequences for the development of potential FL-cDNA simple sequence repeat (SSR) markers. We screened 10,608 P. pu...

    Authors: Yuan Lin, Jiang-Jie Lu, Miao-Dan Wu, Ming-Bing Zhou, Wei Fang, Yuji Ide and Ding-Qin Tang
    Citation: SpringerPlus 2014 3:486
  35. Phytoene synthase (PSY) is the first rate-limiting regulatory enzyme in the carotenoid biosynthesis pathway. In order to modify the floral color pattern by reducing carotenoid contents, a phytoene synthase-RNAi c...

    Authors: Jian-Xin Liu, Chung-Yi Chiou, Chin-Hui Shen, Peng-Jen Chen, Yao-Chung Liu, Chin-Der Jian, Xiao-Lan Shen, Fu-Quan Shen and Kai-Wun Yeh
    Citation: SpringerPlus 2014 3:478
  36. Metabolomics has proven an useful tool for systems biology. Here we have used a metabolomics approach to identify conditions in which de novo expression of an established tumor marker, galectin-3, would confer a ...

    Authors: Pedro Starzynski Bacchi, Antonio Carlos Bloise, Silvina Odete Bustos, Lara Zimmermann, Roger Chammas and Said Rahnamaye Rabbani
    Citation: SpringerPlus 2014 3:470
  37. Current investigation characterized export quality shrimp samples in terms of pathogenic load along with the drug-resistance traits of the isolates, and detected the major virulent genes present in those isola...

    Authors: Rashed Noor, Md Faqrul Hasan and M Majibur Rahman
    Citation: SpringerPlus 2014 3:469
  38. Tropical evergreen forests in northeast India are a biological hot spot for conservation of flora and fauna. Little is known, however, about tiger abundance, which is a flagship species for tropical evergreen ...

    Authors: Randeep Singh, Devendra Singh Chauhan, Sudhanshu Mishra, Paul R Krausman and Surendra Prakash Goyal
    Citation: SpringerPlus 2014 3:462
  39. Newcastle disease represents the most severe poultry disease responsible for marked economic losses in Ethiopia. To provide a molecular characterization of Newcastle disease viruses circulating in this country...

    Authors: Delesa Damena Mulisa, Menbere Kidane W/Kiros, Redeat Belaineh Alemu, Melaku Sombo Keno, Alice Furaso, Alireza Heidari, Tesfaye Rufael Chibsa and Hassen Chaka Chunde
    Citation: SpringerPlus 2014 3:459