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Biomedical and Life Sciences

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  1. This study was conducted to assess the reproductive biology and early breeding behaviour of female Oreochromis niloticus reared in monoculture and polyculture with Clarias gariepinus in earthen ponds for 8 months...

    Authors: A P Shoko, S M Limbu, H D J Mrosso and Y D Mgaya
    Citation: SpringerPlus 2015 4:275
    Content type: Research Published on:

  2. Parathyroid hormone-related protein (PTHrP) inhibits proliferation of several lung cancer cell lines, but the signaling mechanism has not been established. This study tested the hypotheses that growth inhibiti...

    Authors: Philippe R Montgrain, Jennifer Phun, Ryan Vander Werff, Rick A Quintana, Ariea J Davani and Randolph H Hastings
    Citation: SpringerPlus 2015 4:268
    Content type: Research Published on:

  3. The paired box-7 (pax7) transcription factor expressed in satellite cells (SCs) is an essential regulator of skeletal muscle growth and regeneration in vertebrates including fish. Characterization of rainbow trou...

    Authors: Kalyan C Chapalamadugu, Brenda M Murdoch, Barrie D Robison, Rodney A Hill and Gordon K Murdoch
    Citation: SpringerPlus 2015 4:263
    Content type: Research Published on:

  4. The symbiotic, nitrogen-fixing bacterium Sinorhizobium meliloti has been widely studied due to its ability to improve crop yields through direct interactions with leguminous plants. S. meliloti AK21 is a wild typ...

    Authors: María Dolores Molina-Sánchez, José Antonio López-Contreras, Nicolás Toro and Manuel Fernández-López
    Citation: SpringerPlus 2015 4:259
    Content type: Research Published on:

  5. Although the expression and epigenetic status of imprinted genes have been extensively studied in a number of species, less is known about the genomic imprinting in rabbits. Neuronatin (Nnat) plays significant ro...

    Authors: Feifei Duan, Xianju Chen, Lin Yuan, Yuning Song, Anfeng Wang, Qingyan Lv, Zhanjun Li and Liangxue Lai
    Citation: SpringerPlus 2015 4:257
    Content type: Research Published on:

  7. Domesticated chicks are precocial and therefore have relatively well-developed feeding behavior. The role of hypothalamic neuropeptides in food-intake regulation in chicks has been reported for decades. Howeve...

    Authors: Phuong V Tran, Vishwajit S Chowdhury, Mao Nagasawa and Mitsuhiro Furuse
    Citation: SpringerPlus 2015 4:252
    Content type: Research Published on:

  9. Genetics of micronutrients and their relationships with grain yield and other traits have a direct bearing on devising effective strategies for breeding biofortified crop cultivars. A line × tester study of 19...

    Authors: Anand Kanatti, Kedar N Rai, Kommineni Radhika, Mahalingam Govindaraj, Kanwar L Sahrawat and Aluri S Rao
    Citation: SpringerPlus 2014 3:763
    Content type: Research Published on:

  10. The aim of the paper was to estimate the accuracy of the metrology of an installed indirect on-line sensor system based on the automated California Mastitis Test (CMT) with focus on the prior established devic...

    Authors: Anne-Christin Neitzel, Eckhard Stamer, Wolfgang Junge and Georg Thaller
    Citation: SpringerPlus 2014 3:760
    Content type: Research Published on:

  11. Pest eradication strategies that use pesticides require application methods that have the lowest environmental and human health impact while maintaining the highest probability of success. This is highly impor...

    Authors: Tara M Strand, Carol A Rolando, Brian Richardson, Stefan Gous, Martin KF Bader and Don Hammond
    Citation: SpringerPlus 2014 3:750
    Content type: Short report Published on:

  12. Osmotic Shock is known to negatively affect growth rate along with an extended lag phase. The reduction in growth rate can be characterized as burden due to the osmotic stress. Studies have shown that producti...

    Authors: Pushkar Malakar, Vivek K Singh, Richa Karmakar and Kareenhalli V Venkatesh
    Citation: SpringerPlus 2014 3:748
    Content type: Research Published on:

  13. A single GAG codon deletion in the gene encoding torsinA is linked to most cases of early-onset torsion dystonia. TorsinA is an ER-localized membrane-associated ATPase from the AAA+ superfamily with an unknown...

    Authors: Hui Li, Hui-Chuan Wu, Zhonghua Liu, Lucia F Zacchi, Jeffrey L Brodsky and Michal Zolkiewski
    Citation: SpringerPlus 2014 3:743
    Content type: Research Published on:

  14. Previously identified fungal pectinase producers of the species Aspergillus sojae were used for optimization of polygalacturonase production in solid-state fermentation applying Design of Experiment. The effects ...

    Authors: Doreen Heerd, Sonja Diercks-Horn and Marcelo Fernández-Lahore
    Citation: SpringerPlus 2014 3:742
    Content type: Research Published on:

  15. Pharmaceutical companies incorporate different features into the trials for new drug applications (NDAs) to render them efficient, making use of their experience. The objective of this analysis was to examine ...

    Authors: Satoshi Fukunaga, Makiko Kusama and Shunsuke Ono
    Citation: SpringerPlus 2014 3:740
    Content type: Research Published on:

  16. Present study attempted to assess the level of microbiological contamination in oral herbal medicines, frequently used for medications, through conventional cultural and biochemical tests along with the antibi...

    Authors: Marufa Sharmin, Ifra Tun Nur, Mrityunjoy Acharjee, Saurab Kishore Munshi and Rashed Noor
    Citation: SpringerPlus 2014 3:739
    Content type: Research Published on:

  19. We aimed to determine whether the multidrug-resistance-proteins MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the antimetabolites cytarabine (Ara-C), gemcitabine (GEM), and the L-nucleoside analog troxaci...

    Authors: Auke D Adema, Karijn Floor, Kees Smid, Richard J Honeywell, George L Scheffer, Gerrit Jansen and Godefridus J Peters
    Citation: SpringerPlus 2014 3:732
    Content type: Research Published on:

  20. Epidemiological studies show a positive association between adequate sleep and good health. Further, disrupted sleep may increase the risk for CNS diseases, such as stroke and Alzheimer’s disease. However, the...

    Authors: Alisa S Elliott, Jason D Huber, James P O’Callaghan, Charles L Rosen and Diane B Miller
    Citation: SpringerPlus 2014 3:728
    Content type: Review Published on:

  21. Improvement in animal disease control and prevention is dependent on several factors including farmers’ uptake of new technologies and skills, particularly in developing countries. Extension is the means by wh...

    Authors: Joerg Henning, Than Hla and Joanne Meers
    Citation: SpringerPlus 2014 3:726
    Content type: Research Published on:

  22. We investigated seventy-four ultra-mountain bikers (MTBers) competing in the solo category in the first descriptive field study to detail nutrition habits and the most common food before during and after the 2...

    Authors: Daniela Chlíbková, Beat Knechtle, Thomas Rosemann, Ivana Tomášková, Vlastimil Chadim and Marcus Shortall
    Citation: SpringerPlus 2014 3:715
    Content type: Research Published on:

  23. Tuber rot disease is a major constraint to white yam (Dioscorea rotundata) production, accounting for 50-60% of annual yield losses in Nigeria. The main method of control using synthetic fungicides is being disco...

    Authors: Victor Ohileobo Dania, Olubunmi Omowunmi Fadina, Maria Ayodele and P Lava Kumar
    Citation: SpringerPlus 2014 3:711
    Content type: Research Published on:

  24. To determine the prevalence of substandard drugs in urban (Ulaanbaatar) and rural (selected provinces) areas of Mongolia, samples of 9 common, therapeutically important drugs were collected from randomly selec...

    Authors: Daariimaa Khurelbat, Gereltuya Dorj, Enkhtuul Bayarsaikhan, Munkhdelger Chimedsuren, Tsetsegmaa Sanjjav, Takeshi Morimoto, Michael Morley and Katharine Morley
    Citation: SpringerPlus 2014 3:709
    Content type: Research Published on:

  25. Forest ecosystem harbour a large number of biotic components where cellulolytic microorganisms participate actively in the biotransformation of dead and decaying organic matter and soil nutrient cycling. This ...

    Authors: Sailendra Goyari, Shantibala S Devi, Mohan C Kalita and Narayan C Talukdar
    Citation: SpringerPlus 2014 3:700
    Content type: Research Published on:

  26. Pharmacovigilance plays a consequential role in the surveillance of adverse drug reactions, which is provoked by the drugs used to cure diseases. Adverse drug reactions (ADRs) produce detrimental or undesirabl...

    Authors: Ram Kumar Sahu, Rajni Yadav, Pushpa Prasad, Amit Roy and Shashikant Chandrakar
    Citation: SpringerPlus 2014 3:695
    Content type: Review Published on:

  27. We investigated age and performance in distance-limited ultra-marathons held from 50 km to 1,000 km. Age of peak running speed and running speed of the fastest competitors from 1969 to 2012 in 50 km, 100 km, 2...

    Authors: Tobias Romer, Christoph Alexander Rüst, Matthias Alexander Zingg, Thomas Rosemann and Beat Knechtle
    Citation: SpringerPlus 2014 3:693
    Content type: Research Published on:

  30. The Colletotrichum gloeosporioides species complex is among the most destructive fungal plant pathogens in the world, however, identification of member species which are of quarantine importance is impacted by a ...

    Authors: Sephra N Rampersad
    Citation: SpringerPlus 2014 3:684
    Content type: Research Published on:

  31. Improvements on growth and carcass traits in the poultry industry have been achieved by intense selection for heavier chickens at early ages. This faster growth has caused serious problems due to insufficient ...

    Authors: Marcelo B Fornari, Ricardo Zanella, Adriana MG Ibelli, Lana T Fernandes, Maurício E Cantão, Vanete Thomaz-Soccol, Mônica C Ledur and Jane O Peixoto
    Citation: SpringerPlus 2014 3:682
    Content type: Research Published on:

  33. The dearth of African giant catfish Heterobranchus bidorsalis seeds poses great threat to its aquaculture and biodiversity, hence detailed knowledge and understanding of its embryology is indispensable for its ar...

    Authors: Wasiu Adekunle Olaniyi and Ofelia Galman Omitogun
    Citation: SpringerPlus 2014 3:677
    Content type: Research Published on:

  34. The sea cucumber (Holothuria atra) extracts have been evaluated for the presence of bioactive compounds and various biological activities. The methanol extracts showed anti proliferative activities against the He...

    Authors: Devaraj Isaac Dhinakaran and Aaron Premnath Lipton
    Citation: SpringerPlus 2014 3:673
    Content type: Research Published on:

  35. Hormonal variations during the menstrual cycle (MC) may influence trainability of strength. We investigated the effects of a follicular phase-based strength training (FT) on muscle strength, muscle volume and ...

    Authors: Eunsook Sung, Ahreum Han, Timo Hinrichs, Matthias Vorgerd, Carmen Manchado and Petra Platen
    Citation: SpringerPlus 2014 3:668
    Content type: Research Published on:

  39. Escherichia coli stationary-phase (SP) cells contain relaxed DNA molecules and recover DNA supercoiling once nutrients become available. In these cells, the reactivation of DNA gyrase, which is a DNA topoisomeras...

    Authors: Alejandra Gutiérrez-Estrada, Jesús Ramírez-Santos and María del Carmen Gómez-Eichelmann
    Citation: SpringerPlus 2014 3:656
    Content type: Research Published on:

  40. The aims of the present study were to investigate the changes in the age and in swimming performance of finalists in World Championships (1994–2013) and Olympic Games (1992–2012) competing in all events/races ...

    Authors: Stefan König, Fabio Valeri, Stefanie Wild, Thomas Rosemann, Christoph Alexander Rüst and Beat Knechtle
    Citation: SpringerPlus 2014 3:652
    Content type: Research Published on:

  42. The major objectives of this work are to estimate the hypertension (HT) frequency in the east of Morocco and to study the relationship between HT, type 2 diabetes and obesity. Our sample is composed of 1628 ad...

    Authors: Abderrahim Ziyyat, Noureddine Ramdani, Nour El Houda Bouanani, Jean Vanderpas, Benyounès Hassani, Abdeslam Boutayeb, Mohammed Aziz, Hassane Mekhfi, Mohammed Bnouham and Abdelkhaleq Legssyer
    Citation: SpringerPlus 2014 3:644
    Content type: Research Published on:

  43. Trichoderma isolates were collected from varied agro-climatic zones of India and screened for high temperature and salinity tolerance. Among all the isolates tested, T. asperellum, TaDOR673 was highly tolerant to...

    Authors: Sowmya Poosapati, Prasad Durga Ravulapalli, Navaneetha Tippirishetty, Dinesh Kumar Vishwanathaswamy and Sarada Chunduri
    Citation: SpringerPlus 2014 3:641
    Content type: Research Published on:

  47. An investigation into the mechanism of antihyperlipidemic action of 2-chloromethyl-5,6,7,8-tetrahydrobenzo(b)thieno[2,3-d]pyrimidin-4(3H)-one (LM-1554) was carried out through docking experiments with six differe...

    Authors: Vijay M Khedkar, Nikhilesh Arya, Evans C Coutinho, Chamanlal J Shishoo and Kishor S Jain
    Citation: SpringerPlus 2014 3:628
    Content type: Research Published on:

  48. Infections with Streptococcus spp. were observed in Nile tilapia cultured in net cages in Lake Sentani, Papua, Indonesia. Clinical signs included exophthalmia, erratic swimming, ascites in abdominal cavity, and e...

    Authors: Hilal Anshary, Rio A Kurniawan, Sriwulan Sriwulan, Ramli Ramli and Dolores V Baxa
    Citation: SpringerPlus 2014 3:627
    Content type: Research Published on:

  49. This study aimed to investigate muscle length-related electromyography (EMG) of the iliopsoas (IL) and other hip flexor muscles to determine individual muscle contributions to the hip flexion torque. Ten healt...

    Authors: Takumi Jiroumaru, Toshiyuki Kurihara and Tadao Isaka
    Citation: SpringerPlus 2014 3:624
    Content type: Research Published on: