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  1. Based on Victor Herbert’s model for sequential stages in the development of vitamin B12 deficiency, the holotranscobalamin (HoloTC) immunoassay has controversially been promoted as a more specific and sensitive ...

    Authors: Paul Henry Golding
    Citation: SpringerPlus 2016 5:184
  2. To examine the effect of exercise volume at a fixed intensity on changes in aerobic fitness. Ninety-two overweight/obese individuals (BMI 25–40 kg m2), age 18–30 years, 50 % women, completed a 10 mo, 5 d wk−1 sup...

    Authors: Matthew M. Schubert, Richard A. Washburn, Jeffery J. Honas, Jaehoon Lee and Joseph E. Donnelly
    Citation: SpringerPlus 2016 5:183
  3. To clone and examine expression profiles of DlRan genes during somatic embryogenesis in Dimocarpus longan Lour. Thirty cDNA sequences and two genomic sequences encoding DlRan proteins were isolated from longan e...

    Authors: Zhizhen Fang, Chengchun Lai, Yaling Zhang and Zhongxiong Lai
    Citation: SpringerPlus 2016 5:181
  4. Multicentric reticulohistiocytosis is a rare disease affecting skin and joints primarily and rarely other organs. We present a case report of this disease and an extensive review of the literature. We reviewed...

    Authors: Saad Tariq, Steven T. Hugenberg, Stefanie A. Hirano-Ali and Hassan Tariq
    Citation: SpringerPlus 2016 5:180
  5. Aiming to embed large amount of data while minimize the sum of costs of all changed pixels, a novel high capacity data hiding scheme based on (7, 4) Hamming code is realized by a family of algorithms. Firstly, n ...

    Authors: Zekun Cao, Zhaoxia Yin, Honghe Hu, Xiangping Gao and Liangmin Wang
    Citation: SpringerPlus 2016 5:175
  6. Detection and quantification of lysine degradation metabolites in plasma is necessary for the diagnosis and follow-up of diseases such as pyridoxine-dependent epilepsy. The principal metabolites involved in t...

    Authors: Izabella A. Pena, Lygia A. Marques, Angelo B. A. Laranjeira, José A. Yunes, Marcos N. Eberlin and Paulo Arruda
    Citation: SpringerPlus 2016 5:172
  7. Viscosupplementaion by intra-articular injection of hyaluronic acid (HA) is a therapeutic modality for treating osteoarthritis of the knee, of the hip and less frequently of other joints. During viscosupplemen...

    Authors: Thierry Conrozier, Jeremy Patarin, Pierre Mathieu and Marguerite Rinaudo
    Citation: SpringerPlus 2016 5:170
  8. There is an increasing interest to develop various lactic acid bacteria (LAB) species as mucosal delivery vehicles, for which the development of a variety of cloning and expression systems for these bacteria i...

    Authors: Namfon Suebwongsa, Viraphong Lulitanond, Baltasar Mayo, Panjamaporn Yotpanya and Marutpong Panya
    Citation: SpringerPlus 2016 5:169
  9. A highly oil-polluted soil from Krasnoe in North-West Russia was used to investigate the degradation of organic pollutants during electrodialytic remediation. Removal efficiencies were up to 70 % for total hy...

    Authors: Kristine B. Pedersen, Tore Lejon, Pernille E. Jensen and Lisbeth M. Ottosen
    Citation: SpringerPlus 2016 5:168
  10. Total knee replacement has reliably been shown to have a beneficial effect in knee osteoarthritis; however, around 17 % of patients are dissatisfied with the result. A commonly proposed mechanism driving the d...

    Authors: Timothy Barlow, Tamsyn Clark, Mark Dunbar, Andrew Metcalfe and Damian Griffin
    Citation: SpringerPlus 2016 5:167
  11. Specific inhibitors of Cytochrome P4502C9 enzyme (CYP2C9) viz. clopidogrel, fenofibrate fluvoxamine and sertraline at concentration of 50, 100, 150 and 200 µM were employed to investigate the nature of enzyme...

    Authors: G. Shyam Prasad, K. Srisailam and R. B. Sashidhar
    Citation: SpringerPlus 2016 5:166
  12. The average topological overlap of two graphs of two consecutive time steps measures the amount of changes in the edge configuration between the two snapshots. This value has to be zero if the edge configurati...

    Authors: Kathrin Büttner, Jennifer Salau and Joachim Krieter
    Citation: SpringerPlus 2016 5:165
  13. The treatment goals for metastatic breast cancer (MBC) are prolonging survival and improving the quality of life. Eribulin, a non-taxane tubulin inhibitor, demonstrated improved survival in previous studies an...

    Authors: Tsutomu Takashima, Shinya Tokunaga, Seika Tei, Shigehiko Nishimura, Hidemi Kawajiri, Shinichiro Kashiwagi, Shigehito Yamagata, Satoru Noda, Takeo Nishimori, Yoko Mizuyama, Takeshi Sunami, Kenji Tezuka, Katsumi Ikeda, Yoshinari Ogawa, Naoyoshi Onoda, Tetsuro Ishikawa…
    Citation: SpringerPlus 2016 5:164
  14. Although the lung is the primary site of infection of tuberculosis, Mycobacterium tuberculosis is capable of causing infection at other sites. In 5–10 % such extra-pulmonary tuberculosis is located in bone tissue...

    Authors: Shrabanti Sarkar, Muyalo G. Dlamini, Debapriya Bhattacharya, Olubisi T. Ashiru, A. Willem Sturm and Prashini Moodley
    Citation: SpringerPlus 2016 5:163
  15. Sri Lanka is undergoing nutritional transition and diet-related chronic diseases are emerging as an important health problem. Currently, no validated food frequency questionnaire (FFQ) exists to measure habitu...

    Authors: Ranil Jayawardena, Nuala M. Byrne, Mario J. Soares, Prasad Katulanda and Andrew P. Hills
    Citation: SpringerPlus 2016 5:162
  16. The changes of coagulation parameters in preoperative fracture patients reflect the coagulation status before surgery. We did retrospective assessment of preoperative fracture patients (n = 113) admitted to t...

    Authors: Chen Liu, Ying Song, Jingzhong Zhao, Qinzhu Xu, Ning Liu, Lei Zhao, Songsong Lu and Hui Wang
    Citation: SpringerPlus 2016 5:161
  17. Enteroviruses (EV) are responsible for a wide range of clinical diseases in humans. Though studied broadly in several regions of the world, the genetic diversity of human enteroviruses (HEV) circulating in the...

    Authors: Silvanos M. Opanda, Fred Wamunyokoli, Samoel Khamadi, Rodney Coldren and Wallace D. Bulimo
    Citation: SpringerPlus 2016 5:158
  18. To clarify the hemodynamic changes under balloon occlusion of the hepatic artery and to identify predictors of the short-term therapeutic effect (TE) after balloon-occluded transcatheter arterial chemoemboliza...

    Authors: Yoshiki Asayama, Akihiro Nishie, Kousei Ishigami, Yasuhiro Ushijima, Yukihisa Takayama, Daisuke Okamoto, Nobuhiro Fujita, Koichiro Morita and Hiroshi Honda
    Citation: SpringerPlus 2016 5:157
  19. The definition of the number and nature of the signal transduction pathways involved in the pathogenesis and the identification of the molecules promoting metastasis spread might improve the knowledge of the n...

    Authors: Vincenza Rita Lo Vasco, Martina Leopizzi, Valeria Di Maio and Carlo Della Rocca
    Citation: SpringerPlus 2016 5:156
  20. A clinical target volume (CTV) to planning target volume (PTV) margin recipes was routinely used to ensure dose was actually delivered to target for all (most) patients. Currently used margin recipes were asso...

    Authors: Xiang Zhang, Guo-ping Shan, Ji-ping Liu and Bin-bing Wang
    Citation: SpringerPlus 2016 5:153
  21. A pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) is a signature of favorable prognosis in breast cancer. The aim of this study was to assess the accuracy of magnetic resonance imaging (...

    Authors: Takayo Fukuda, Rie Horii, Naoya Gomi, Yumi Miyagi, Shunji Takahashi, Yoshinori Ito, Futoshi Akiyama, Shinji Ohno and Takuji Iwase
    Citation: SpringerPlus 2016 5:152
  22. The purpose of this study was to investigate whether the knee and ankle angles at contact during running were related to the elastic properties of tendon structures in knee extensors and plantar flexors and pe...

    Authors: Keitaro Kubo, Daisuke Miyazaki, Kenji Yamada, Shozo Shimoju and Naoya Tsunoda
    Citation: SpringerPlus 2016 5:151
  23. Pulmonary hemosiderosis is a disorder with unknown cause and characterized by hemosiderin appreciation in alveolar interstitium from decomposed hemoglobin following alveolar capillary bleeding, which finally l...

    Authors: Shuhan Peng, Yunbin Xiao, Jinwen Luo, Renwei Chen, Peng Huang, Pingbo Liu and Xicheng Deng
    Citation: SpringerPlus 2016 5:150
  24. It has been reported that exercise under hypoxic conditions induces reduced muscle oxygenation, which could be related to enhanced activity on electromyography (EMG). Although it has been demonstrated that exe...

    Authors: Daisuke Kume, Shogo Akahoshi, Takashi Yamagata, Toshihiro Wakimoto and Noriki Nagao
    Citation: SpringerPlus 2016 5:149
  25. To evaluate SNPs (single nucleotide polymorphism) in PROC (protein C gene) associated with pulmonary embolism (PE) susceptibility in North Chinese Han population. A case-control study design was used, and patien...

    Authors: Zengliang Wang, Tianhe Wang, Jianyong Chang, Hua Li, Chengdong Wang, Yongyong Li, Xuhe Lang, Shimei Jing, Guoqing Zhang and Yuting Wang
    Citation: SpringerPlus 2016 5:147
  26. Capecitabine, a fluoropyrimidine prodrug, has been a frequently chosen ligand for the last one and half decades to inhibit thymidylate synthase (TYMS) for treatment of colorectal cancer. TYMS is a key enzyme f...

    Authors: Adhip Rahman, Mohammad Mazharol Hoque, Mohammad A. K. Khan, Mohammed G. Sarwar and Mohammad A. Halim
    Citation: SpringerPlus 2016 5:146
  27. The ftsZ gene from Xanthomonas oryzae pv. Oryzae was amplified by PCR with the specific primers, and the recombinant plasmid pET-22b-ftsZ was constructed successfully. The FtsZ with a 6× His tag was overexpressed...

    Authors: Leng Dai, Yunhong Huang, Yang Chen and Zhong-er Long
    Citation: SpringerPlus 2016 5:145
  28. To determine the chest wall movement of each patient during deep inspiratory breath hold (DIBH) and expiratory breath hold (EBH) in postoperative breast cancer patients. Postoperative breast cancer patients wh...

    Authors: C. Lowanichkiattikul, M. Dhanachai, C. Sitathanee, S. Khachonkham and P. Khaothong
    Citation: SpringerPlus 2016 5:144
  29. Mycoplasma pneumoniae (M. pneumoniae) frequently causes community-acquired respiratory tract infection and often presents as atypical pneumonia. Following airborne infection and a long in...

    Authors: Thomas Horvath, Urs Fischer, Lionel Müller, Sebastian Ott, Claudio L. Bassetti, Roland Wiest, Parham Sendi and Joerg C. Schefold
    Citation: SpringerPlus 2016 5:143
  30. To examine whether the association between spinal alignment and sacral anatomical orientation (SAO) can be detected in skeletal populations, by comparing SAO values in individuals with a typical SD to individu...

    Authors: Smadar Peleg, Gali Dar, Nili Steinberg, Youssef Masharawi and Israel Hershkovitz
    Citation: SpringerPlus 2016 5:141
  31. Murine mammary stem/progenitor cell isolation has been routinely used in many laboratories, yet direct comparison among different methods is lacking. In this study, we compared two frequently used digestion me...

    Authors: Hui Gao, Qiaoxiang Dong, Yuanhong Chen, Fuchuang Zhang, Anqi Wu, Yuanshuo Shi, Abhik Bandyopadhyay, Benjamin J. Daniel, Changjiang Huang and Lu-Zhe Sun
    Citation: SpringerPlus 2016 5:140
  32. Salinity is one of most significant environmental stresses. Marigold is moderately tolerant to salinity stress. Therefore, in this study, the fresh weights of roots and shoots, rootFW/shootFW ratio, moisture cont...

    Authors: Nezihe Koksal, Ayfer Alkan-Torun, Ilknur Kulahlioglu, Ebru Ertargin and Eylul Karalar
    Citation: SpringerPlus 2016 5:139
  33. To investigate how the energy intake of institutionalized long-term-care patients through the regular nontherapeutic meals provision is associated with the nutritional status and the Geriatric Nutritional Risk...

    Authors: Baerbel Sturtzel, Ibrahim Elmadfa and Gerald Ohrenberger
    Citation: SpringerPlus 2016 5:136
  34. To estimate the surgical volume and the incidence of in-hospital complications of RC in Armenia from 2005 to 2012, and to investigate potential risk factors of complications. The study utilized a retrospective...

    Authors: Arman Tsaturyan, Varduhi Petrosyan, Byron Crape, Yeva Sahakyan and Lusine Abrahamyan
    Citation: SpringerPlus 2016 5:134
  35. In 2010, workplace-based assessment (WBA) was formally integrated as a method of formative trainee assessment into 29 basic and higher specialist medical training (BST/HST) programmes in six postgraduate trai...

    Authors: Aileen Barrett, Rose Galvin, Yvonne Steinert, Albert Scherpbier, Ann O’Shaughnessy, Gillian Walsh and Mary Horgan
    Citation: SpringerPlus 2016 5:133
  36. Renal cell carcinoma represents 3 % of all cancers. Around 4–10 % of cases present with inferior vena cava involvement, generally with tumor thrombus. Clinical and preoperative stage will be classified dependi...

    Authors: Vital Hevia, Gaetano Ciancio, Victoria Gómez, Sara Álvarez, Víctor Díez-Nicolás and Francisco Javier Burgos
    Citation: SpringerPlus 2016 5:132
  37. This study aimed to develop a modified Tessari method for producing more sclerosing foam in treatment of extensive venous malformations. Sclerosing foam was produced by using Tessari method and the modified Te...

    Authors: Jie Xu, Yi-fei Wang, An-wei Chen, Tao Wang and Shao-hua Liu
    Citation: SpringerPlus 2016 5:129
  38. Experience with endoscopic retrograde cholangiopancreatography in the pediatric population is limited. The aim of this study was to evaluate the outcomes of ERCP in the pediatric population performed by adult ...

    Authors: Abdullah Emre Yıldırım, Reskan Altun, Serkan Ocal, Murat Kormaz, Figen Ozcay and Haldun Selcuk
    Citation: SpringerPlus 2016 5:128
  39. One of the most important ingredients of felicitous conversation exchanges is the adequate expression of illocutionary force and the achievement of perlocutionary effects, which can be considered essential to ...

    Authors: Javier Gutiérrez-Rexach and Sara Schatz
    Citation: SpringerPlus 2016 5:127