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  1. The main purpose of this study was to investigate parasympathetic reactivation of the heart [evaluated through heart rate recovery (HRR) and HR variability (HRV)] after maximal cardiopulmonary exercise testing...

    Authors: Felipe A Cunha, Adrian W Midgley, Thiago Gonçalves, Pedro P Soares and Paulo Farinatti
    Citation: SpringerPlus 2015 4:100
  2. This study investigated the effects of human trampling on cover, diversity and species richness in an alpine heath ecosystem in northern Sweden. We tested the hypothesis that proximity to trails decreases plan...

    Authors: Annika K Jägerbrand and Juha M Alatalo
    Citation: SpringerPlus 2015 4:95
  3. The purpose of this study was to review all articles published in two temporarily available radiation oncology journals (Radiation Oncology Investigations, Journal of Radiosurgery) in order to evaluate their s...

    Authors: Carsten Nieder, Hans Geinitz, Nicolaus H Andratschke and Anca L Grosu
    Citation: SpringerPlus 2015 4:93
  4. Majority of the known breast cancer susceptibility genes have a role in DNA repair and the most important high-risk genes BRCA1 and BRCA2 are specifically involved in the homologous recombination repair (HRR) of ...

    Authors: Liisa M Pelttari, Johanna I Kiiski, Salla Ranta, Sara Vilske, Carl Blomqvist, Kristiina Aittomäki and Heli Nevanlinna
    Citation: SpringerPlus 2015 4:92
  5. Kombucha is sweetened black tea that is fermented by a symbiosis of bacteria and yeast embedded within a cellulose membrane. It is considered a health drink in many countries because it is a rich source of vit...

    Authors: Nguyen Khoi Nguyen, Ngan Thi Ngoc Dong, Huong Thuy Nguyen and Phu Hong Le
    Citation: SpringerPlus 2015 4:91
  6. Chronic Kidney Disease of unknown etiology (CKDu) has escalated into an epidemic in North Central Province (NCP) and adjacent farming areas in the dry zone of Sri Lanka. Studies have shown that this special ty...

    Authors: Channa Jayasumana, Saranga Fonseka, Ashvin Fernando, Kumudika Jayalath, Mala Amarasinghe, Sisira Siribaddana, Sarath Gunatilake and Priyani Paranagama
    Citation: SpringerPlus 2015 4:90
  7. Monitoring of pest populations is an essential component of integrated pest management. An early warning system helps growers decide when best to take control measures, or when to alter them, should a control ...

    Authors: Zayed S Abdullah, Bethany PJ Greenfield, Katherine J Ficken, James WD Taylor, Martyn Wood and Tariq M Butt
    Citation: SpringerPlus 2015 4:89
  8. This study sought to determine the diagnostic utility of perfusion parameters derived from dynamic contrast-enhanced (DCE) perfusion MRI with a short acquisition time (approximately 3.5 min) in patients with g...

    Authors: Takashi Abe, Yoshifumi Mizobuchi, Kohei Nakajima, Yoichi Otomi, Saho Irahara, Yuki Obama, Mungunkhuyag Majigsuren, Delgerdalai Khashbat, Teruyoshi Kageji, Shinji Nagahiro and Masafumi Harada
    Citation: SpringerPlus 2015 4:88
  9. This paper was aimed at investigating the volatility and conditional relationship among inflation rates, exchange rates and interest rates as well as to construct a model using multivariate GARCH DCC and BEKK ...

    Authors: Ezekiel NN Nortey, Delali D Ngoh, Kwabena Doku-Amponsah and Kenneth Ofori-Boateng
    Citation: SpringerPlus 2015 4:86
  10. Atypical hernias are difficult to diagnose due to their rarity and often unspecific symptoms. In the literature there exist hints to peri-inguinal hernias, i.e. direct lateral hernia, but most of them are form...

    Authors: László Veréb-Amolini, Thomas Betschart, Emilia Kiss, Oliver Ullrich, Stefan Wildi and Elisabeth Eppler
    Citation: SpringerPlus 2015 4:85
  11. Online activity of Internet users has proven very useful in modeling various phenomena across a wide range of scientific disciplines. In our study, we focus on two stylized facts or puzzles surrounding the ini...

    Authors: Tomas Vakrman and Ladislav Kristoufek
    Citation: SpringerPlus 2015 4:84
  12. To investigate associations between patatin-like phospholipase domain-containing 3 (PNPLA3) genotypes and fibrosis and hepatocarcinogenesis in Japanese chronic hepatitis C (CHC) patients.

    Authors: Kazunori Nakaoka, Senju Hashimoto, Naoto Kawabe, Yoshifumi Nitta, Michihito Murao, Takuji Nakano, Hiroaki Shimazaki, Toshiki Kan, Yuka Takagawa, Masashi Ohki, Takamitsu Kurashita, Tomoki Takamura, Toru Nishikawa, Naohiro Ichino, Keisuke Osakabe and Kentaro Yoshioka
    Citation: SpringerPlus 2015 4:83
  13. During a stretch- shortening cycle (SSC), muscle force attained during concentric contractions (shortening phase) is potentiated by the preceding eccentric contractions (lengthening phase). The purpose of this...

    Authors: Atsuki Fukutani, Toshiyuki Kurihara and Tadao Isaka
    Citation: SpringerPlus 2015 4:82
  14. This study aims to examine the current practice of General practitioners (GPs)/primary care physicians in opportunistic screening for prostate cancer (PC) by digital rectal examination(DRE) and Prostate Specif...

    Authors: Weranja KB Ranasinghe, Simon P Kim, Nathan P Papa, Shomik Sengupta, Mark Frydenberg, Damien Bolton, Dimity Pond, Karin Ried, Melanie J Marshall, Raj Persad and Nathan Lawrentschuk
    Citation: SpringerPlus 2015 4:78
  15. Breast MRI added to mammography increases screening sensitivity for high-risk women but false-positive (FP) rates are higher and the optimal screening schedule for coordination with mammography is unclear. We ...

    Authors: Edress Othman, Jue Wang, Brian L Sprague, Tiffany Rounds, YongLi Ji, Sally D Herschorn and Marie E Wood
    Citation: SpringerPlus 2015 4:77
  16. Leaves of Mangifera Indica (MI, mango leaves) and Manihot Utilissima (MU, cassava leaves) are available in tropical regions and are the most accessible vegetal wastes of Kinshasa, capital of Democratic Republic o...

    Authors: Philippe Mambanzulua Ngoma, Serge Hiligsmann, Eric Sumbu Zola, Marc Culot, Thierry Fievez and Philippe Thonart
    Citation: SpringerPlus 2015 4:75
  17. Irreversible electroporation (IRE) is a promising technique for the focal treatment of soft tissue tumors. Even though the local application of an excessive electric field is a potential cause of cardiac arrhy...

    Authors: Katsutoshi Sugimoto, Fuminori Moriyasu, Hirohito Takeuchi, Mayumi Ando, Takatomo Sano, Toshifumi Mori, Yoshihiro Furuichi, Yoshiyuki Kobayashi and Ikuo Nakamura
    Citation: SpringerPlus 2015 4:74
  18. Gastrointestinal stromal tumors (GIST) are uncommon mesenchymal tumors of the gastrointestinal (GI) tract, accounting for 0.1% to 3% of all GI malignancies. Paediatric GIST have an annual incidence of 0.02 per...

    Authors: Mario Lima, Tommaso Gargano, Giovanni Ruggeri, Andrea Pession, Arianna Mariotto and Michela Maffi
    Citation: SpringerPlus 2015 4:73
  19. In order to understand feeding ecology, habitat use and migration of coral reef fish, fatty acid composition was examined in damselfish species Abudefduf bengalensis and A. sexfasciatus collected in the Malaysian...

    Authors: Takaomi Arai, Razikin Amalina and Zainudin Bachok
    Citation: SpringerPlus 2015 4:71
  20. Femoroacetabular impingement is a pathomechanical condition of the hip, which is often treated through arthroscopic techniques. The ensuing immobilization period is associated with decreases in muscle mass and...

    Authors: Sandro Manuel Mueller, Simone Braendli and Marco Toigo
    Citation: SpringerPlus 2015 4:70
  21. In order to assess the changes in sea-surface hydrology and productivity signal from the last glacial to the Holocene; a set of isotopic, geochemical and microgranulometric proxies was used for this study. For...

    Authors: Yassine El Frihmat, Dierk Hebbeln, EL Bachir Jaaidi and Nadia Mhammdi
    Citation: SpringerPlus 2015 4:69
  22. In South Africa, the rate of histologically diagnosed prostate cancer is 40.1 per 100 000 in whites and 14 per 100 000 in blacks. However, blacks have limited access to diagnostic facilities and present late w...

    Authors: Nathaniel Mofolo, Olwethu Betshu, Ogomoditse Kenna, Sarah Koroma, Tlalane Lebeko, Frederik M Claassen and Gina Joubert
    Citation: SpringerPlus 2015 4:67
  23. Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell cancer (RCC), followed by papillary RCC (pRCC). It is important to distinguish these two subtypes because of prognostic differen...

    Authors: Frank Chen, Hannu Huhdanpaa, Bhushan Desai, Darryl Hwang, Steven Cen, Andy Sherrod, Jean-Christophe Bernhard, Mihir Desai, Inderbir Gill and Vinay Duddalwar
    Citation: SpringerPlus 2015 4:66
  24. Diagnosis of extrapulmonary tuberculosis (TB) is often challenging. In this work we discuss the utility of an assay for Lipoarabinomannan (LAM) antibody detection in synovial fluid. LAM is one of the three maj...

    Authors: Giuseppe Passiu, Gian Luca Erre, Pietro Pirina and Leonardo Antonio Sechi
    Citation: SpringerPlus 2015 4:63
  25. Evidence Based Medicine (EBM) is increasingly being applied to inform clinical decision-making in orthopaedic surgery. Despite the promotion of EBM in Orthopaedic Surgery, the adoption of results from high qua...

    Authors: Darren de SA, Patrick Thornley, Nathan Evaniew, Kim Madden, Mohit Bhandari and Michelle Ghert
    Citation: SpringerPlus 2015 4:62
  26. Whole lung lavage is the most effective method to treat pulmonary alveolar proteinosis (PAP), and most potential complications occur often during the lavage process, but few happen after lavage. Theoretically,...

    Authors: Shufang Zhang, Yesong Wang, Zhihao Xu, Liren Ding, Liuhong Wang, Libin Li and Gensheng Zhang
    Citation: SpringerPlus 2015 4:61
  27. RghBNG, a gene of unknown function, was cloned from Rehmannia glutinosa by reverse transcription PCR and rapid amplification of cDNA ends. The full-length cDNA of RghBNG was 548 bp with a282-bp o...

    Authors: Yanqing Zhou, Yonghua Zhang, Jun Wei, Yu Zhang, Jingyun Li, Wanshen Wang, Hongying Duan and Juanjuan Chen
    Citation: SpringerPlus 2015 4:60
  28. An increase of serum creatine kinase (CK) has been observed in clinical studies of nitrogen-containing aminobisphosphonates (N-BPs). Osteoclasts are thought to be the source of the CK, but there is no clear ev...

    Authors: Makoto Tanaka, Hiroshi Mori, Ryoji Kayasuga and Kazuhito Kawabata
    Citation: SpringerPlus 2015 4:59
  29. Mitochondrial DNA (mtDNA) has been proposed to be involved in carcinogenesis and ageing. The mtDNA 4977 bp deletion is one of the most frequently observed mtDNA mutations in human tissues and may play a role i...

    Authors: Jan Dimberg, Thai Trinh Hong, Linh Tu Thi Nguyen, Marita Skarstedt, Sture Löfgren and Andreas Matussek
    Citation: SpringerPlus 2015 4:58
  30. Caffeine, a purine alkaloid drug, has been recognized as a contaminant of water bodies in various climatic regions, however, these environmental caffeine concentrations are the first to be reported in the trop...

    Authors: Quincy A Edwards, Sergei M Kulikov and Leah D Garner-O’Neale
    Citation: SpringerPlus 2015 4:57
  31. Fundus biomicroscopy with the slit lamp as it is practiced widely nowadays was not established until the 1980-es with the introduction of the Volk lenses +90 and +60D. Thereafter little progress has been made ...

    Authors: Marcus-Matthias Gellrich
    Citation: SpringerPlus 2015 4:56
  32. The high expense of newer, more effective adjuvant endocrine therapy agents (aromatase inhibitors [AIs]) for postmenopausal breast cancer contributes to socioeconomic disparities in breast cancer outcomes. Thi...

    Authors: Ann Butler Nattinger, Liliana E Pezzin, Emily L McGinley, John A Charlson, Tina W F Yen and Joan M Neuner
    Citation: SpringerPlus 2015 4:54

    The Erratum to this article has been published in SpringerPlus 2015 4:531

  33. It is well established that the normal human brain contains populations of neural stem/progenitor cells. Recent studies suggest that they migrate toward a variety of CNS tissue injuries. In an investigation of...

    Authors: Jack Griffin Campbell, Douglas C Miller, Diane D Cundiff, Qi Feng and N Scott Litofsky
    Citation: SpringerPlus 2015 4:53
  34. Beta-blockade is contraindicated in severe aortic regurgitation (AR) due to the fear of prolonging diastole and thus aggravate regurgitation. However, this has never been scientifically proven and positive eff...

    Authors: Kristian Eskesen, Niels Thue Olsen, Veronica L Dimaano, Thomas Fritz-Hansen, Peter Sogaard and Theodore P Abraham
    Citation: SpringerPlus 2015 4:52
  35. The tryptophan metabolite, kynurenic acid (KYNA), is a preferential antagonist of the α7 nicotinic acetylcholine receptor at endogenous brain concentrations. Recent studies have suggested that increase of brai...

    Authors: Airi Sekine, Misaki Okamoto, Yuka Kanatani, Mitsue Sano, Katsumi Shibata and Tsutomu Fukuwatari
    Citation: SpringerPlus 2015 4:48