Articles

Folate receptor alpha (FRA) expression in breast cancer: identification of a new molecular subtype and association with triple negative disease

Given that several targeted therapies directed towards folate receptor alpha (FRA) are in late stage clinical development, the sensitive and robust detection of FRA in tissues is of paramount importance relati...

Authors: Daniel J O’Shannessy, Elizabeth B Somers, Julia Maltzman, Robert Smale and Yao-Shi Fu

Evidence for conservation and sustainable use in a fragment of the Atlantic forest in southeastern Brazil by a traditional human group

The use of forest resources by a rural community adjacent to a Biological Reserve was examined using quantitative methods based on the consensus of six local specialists. Plants with trunk diameters at 1.3 m a...

Authors: Alexandre Gabriel Christo, Rejan R Guedes-Bruni, Felipe de Araújo Pinto Sobrinho, Ary Gomes da Silva and Ariane Luna Peixoto

BRCA1 And BRCA2 analysis of Argentinean breast/ovarian cancer patients selected for age and family history highlights a role for novel mutations of putative south-American origin

The spectrum of BRCA1/2 genetic variation in breast-ovarian cancer patients has been scarcely investigated outside Europe and North America, with few reports for South America, where Amerindian founder effects...

Authors: Angela Rosaria Solano, Gitana Maria Aceto, Dreanina Delettieres, Serena Veschi, Maria Isabel Neuman, Eduardo Alonso, Sergio Chialina, Reinaldo Daniel Chacón, Mariani-Costantini Renato and Ernesto Jorge Podestá

Weak forms of continuity in I-double gradation fuzzy topological spaces

In this paper, we introduce and characterize double fuzzy weakly preopen and double fuzzy weakly preclosed functions between I-double gradation fuzzy topological spaces and also study these functions in relation ...

Authors: A Ghareeb

The antifungal effect of cellobiose lipid on the cells of Saccharomyces cerevisiae depends on carbon source

The cellobiose lipid of Cryptococcus humicola, 16-(tetra-O-acetyl-β-cellobiosyloxy)-2-hydroxyhexadecanoic acid, is a natural fungicide. Sensitivity of the cells of Saccharomyces cerevisiae to the fungicide depend...

Authors: Ludmila V Trilisenko, Ekaterina V Kulakovskaya, Tatiana V Kulakovskaya, Alexander Yu Ivanov, Nikita V Penkov, Vladimir M Vagabov and Igor S Kulaev

Meiotic restitution mechanisms involved in the formation of 2n pollen in Agave tequilana Weber and Agave angustifolia Haw

A cytological analysis of the microsporogenesis was carried out in the Agave tequilana and A. angustifolia species. Several abnormalities such as chromosomal bridges, lagging chromosomes, micronuclei, monads, dya...

Authors: Víctor Manuel Gómez-Rodríguez, Benjamín Rodríguez-Garay and Rodrigo Barba-Gonzalez

Calcium/calmodulin-dependent protein kinases in the carotid body: an immunohistochemical study

We determined the presence of Ca²⁺/calmodulin-dependent protein kinases (CaMKs), a family of multifunctional proteins engaged in Ca²⁺-linked signaling, in carotid body chemoreceptor cells which are critical for t...

Authors: Mieczysław Pokorski, Hiroyuki Sakagami and Yasumasa Okada

General Didactics and Instructional Design: eyes like twins A transatlantic dialogue about similarities and differences, about the past and the future of two sciences of learning and teaching

Although General Didactics (GD) and Instructional Design (ID) have not shown many points of contact in the past, there are some obvious parellels from the perspective of their historical development. This will...

Authors: Klaus Zierer and Norbert M Seel

A rugged, precise and accurate new gravimetry method for the determination of gold: an alternative to fire assay method

A new, rugged, precise, accurate and fast primary method of measurement has been proposed for the determination of gold in various gold articles. Precise and accurate measurement of gold is the primary require...

Authors: Nahar Singh

Purification and characterization of a novel plant lectin from Pinellia ternata with antineoplastic activity

A novel Pinellia ternata lectin was purified from the bulbs of a Chinese herb Pinellia ternata using a combination of hydrophobic chromatography and DEAE-ion exchange chromatography. The lectin was found to be a ...

Authors: Zhenyu Zuo, Handong Fan, Xue Wang, Wei Zhou and Lingling Li

A gating mechanism for border node assisted association of wireless personal area networks

IEEE 802.15.4 based Wireless Personal Area Networks (WPANs) are envisioned to play a vital role in the application centric ubiquitous networks. In IEEE802.15.4 networks, the use of non-interfering logical chan...

Authors: Saima Zafar, Ali Hammad Akbar and Sana Jabbar

Development and initial evaluation of a smartphone application based on acceptance and commitment therapy

An intervention, consisting of an ACT-based smartphone-application and a web-based psychoeducation, has been developed. The smartphone-application, together with the psychoeducation, aims to function as a self...

Authors: Kien Hoa Ly, JoAnne Dahl, Per Carlbring and Gerhard Andersson

Three novel F8 mutations in sporadic haemophilia A cases

Authors: Rashid Hussain, Noman Bin Abid, Sajjad Hussain, Zeeshan Shaukat, Mudassir Altaf, Sara Altaf and Gulzar Niazi

Root anoxia effects on physiology and emissions of volatile organic compounds (VOC) under short-and long-term inundation of trees from Amazonian floodplains

Volatile organic compound (VOC) emissions are affected by a variety of biotic and abiotic factors such as light intensity, temperature, CO₂ and drought. Another stress factor, usually overlooked but very importan...

Authors: Araceli Bracho-Nunez, Nina Maria Knothe, Wallace R Costa, Liberato R Maria Astrid, Betina Kleiss, Stefanie Rottenberger, Maria Teresa Fernandez Piedade and Jürgen Kesselmeier

The hybrid block iterative algorithm for solving the system of equilibrium problems and variational inequality problems

In this paper, we construct the hybrid block iterative algorithm for finding a common element of the set of common fixed points of an infinite family of closed and uniformly quasi - ϕ- asymptotically nonexpansive...

Authors: Siwaporn Saewan and Poom Kumam

Unified approach to growth and aging in biological, technical and biotechnical systems

Complex systems, in many different scientific sectors, show coarse-grain properties with simple growth laws with respect to fundamental microscopic algorithms. We propose a classification scheme of growth laws...

Authors: Paolo Castorina and Philippe Blanchard

A simple proof of orientability in colored group field theory

Group field theory is an emerging field at the boundary between Quantum Gravity, Statistical Mechanics and Quantum Field Theory and provides a path integral for the gluing of n-simplices. Colored group field t...

Authors: Francesco Caravelli

Intimate partner violence against women and its related immigration stressors in Pakistani immigrant families in Germany

This paper addresses the issue of intimate partner violence against women and its related immigration stressors in Pakistani immigrant families in Germany. Drawing on 32 in-depth interviews with Pakistani wome...

Authors: Rubeena Zakar, Muhammad Z Zakar, Thomas Faist and Alexander Kraemer

The age-phenome database

Data linking specific ages or age ranges with disease are abundant in biomedical literature. However, these data are organized such that searching for age-phenotype relationships is difficult. Recently, we des...

Authors: Nophar Geifman and Eitan Rubin

Mass spectrometric analysis of prefrontal cortex proteins in schizophrenia and bipolar disorder

Schizophrenia and bipolar disorder are the two most serious and debilitating neuropsychiatric disorders that share many characteristics, both symptomatic and epidemiological. There has yet to be a single diagn...

Authors: Shaheen E Lakhan

Chronic traumatic encephalopathy: the dangers of getting "dinged"

Chronic traumatic encephalopathy (CTE) is a form of neurodegeneration that results from repetitive brain trauma. Not surprisingly, CTE has been linked to participation in contact sports such as boxing, hockey ...

Authors: Shaheen E Lakhan and Annette Kirchgessner

Computer-assisted coloring and illuminating based on a region-tree structure

Colorization and illumination are key processes for creating animated cartoons. Computer assisted methods have been incorporated in animation/illustration systems to reduce the artists' workload. This paper pr...

Authors: Renata Nascimento, Fabiane Queiroz, Allan Rocha, Tsang Ing Ren, Vinicius Mello and Adelailson Peixoto