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  1. Head and neck paragangliomas are rare tumours and can arise as a part of inherited syndromes. Their association with thymic tumour is not well known.

    Authors: G. Bano, D. Sennik, M. Kenchaiah, Ye Kyaw, Katie Snape, V. Tripathi, P. Wilson, I. Vlahos, I. Hunt and S. Hodgson
    Citation: SpringerPlus 2015 4:632
  2. This phase I/II neoadjuvant trial (ClinicalTrials.gov identifier NCT00066443) determined maximally-tolerated doses (MTD), dose-limiting toxicities, response-to-therapy, and explored the role of novel response ...

    Authors: Maureen Elizabeth Trudeau, Judith-Anne W. Chapman, Baoqing Guo, Mark J. Clemons, Rebecca A. Dent, Roberta A. Jong, Harriette J. Kahn, Kathleen I. Pritchard, Lei Han, Patti O’Brien, Lois E. Shepherd and Amadeo M. Parissenti
    Citation: SpringerPlus 2015 4:631
  3. The increasing frequency of destructive wildfires, with a consequent loss of life and property, has led to fire and land management agencies initiating extensive fuel management programs. This involves long-te...

    Authors: Ramya Rachmawati, Melih Ozlen, Karin J. Reinke and John W. Hearne
    Citation: SpringerPlus 2015 4:630
  4. In this paper, we examine the issue of strategic industrial location selection in uncertain decision making environments for implanting new industrial corporation. In fact, the industrial location issue is typ...

    Authors: Omar Boutkhoum, Mohamed Hanine, Tarik Agouti and Abdessadek Tikniouine
    Citation: SpringerPlus 2015 4:628
  5. Clostridium difficile is recognized as a major cause of nosocomial acquired antibiotic-associated diarrhea and pseudomembranous colitis. It is a significant financial burden on modern hea...

    Authors: Abolfazl Khoshdel, Roya Habibian, Neda Parvin, Abbas Doosti, Fatemeh Famouri, Ali Eshraghi and Massoud Hafizi
    Citation: SpringerPlus 2015 4:627
  6. Bibliometric studies, which involve the use of statistical methods, are increasingly being used for research assessment. A bibliometric analysis was conducted to evaluate the publication pattern of methaemoglo...

    Authors: Sa’ed H. Zyoud, Samah W. Al-Jabi, Waleed M. Sweileh, Suleiman Al-Khalil, Malik Alqub and Rahmat Awang
    Citation: SpringerPlus 2015 4:626
  7. Despite being routinely prescribed worldwide for several years, data regarding the safety, efficacy, and survival benefit of eribulin in clinical settings for the treatment of metastatic breast cancer (MBC) ar...

    Authors: Junichiro Watanabe
    Citation: SpringerPlus 2015 4:625
  8. Previous cost-effectiveness analyses (CEAs) of abiraterone for castration-resistant prostate cancer (CRPC) patients have not shown favorable results for this new drug. These CEAs were generally conducted based...

    Authors: Susumu Kunisawa, Chihiro Tange and Kojiro Shimozuma
    Citation: SpringerPlus 2015 4:624
  9. Macmillan Cancer Support UK have developed an electronic Holistic Needs Assessment (eHNA) to: (1) help people living with cancer express all their needs, (2) help those helping them better target support. eHNA...

    Authors: Austyn Snowden and Mick Fleming
    Citation: SpringerPlus 2015 4:623
  10. This study analyzed baroreflex sensitivity, heart rate and systolic blood pressure variabilities during an oral 1 week administration of prednisone. This study examined the hypothesis that prednisone might cha...

    Authors: F. Cottin, V. Malcurat, H. Zorgati, F. Prieur, Z. Labsy, M. C. Do, O. Gagey and K. Collomp
    Citation: SpringerPlus 2015 4:622
  11. This study aims to reveal the importance of chemical senses in glucose kinetics and autonomic nervous activity by imposing interventions during glucose intake. The glucose-loading test was applied to seven hea...

    Authors: Tadataka Tsuji, Susumu Tanaka, Kumiko Kida, Sanam Bakhshishayan, Mikihiko Kogo and Takashi Yamamoto
    Citation: SpringerPlus 2015 4:621
  12. Nationally Appropriate Mitigation Actions (NAMAs) involve the collaboration on reduction of greenhouse gas (GHG) emissions in developing countries with suitable countermeasures relevant to the state of technol...

    Authors: Puttipong Chunark, Panida Thepkhun, Kamphol Promjiraprawat, Pornphimol Winyuchakrit and Bundit Limmeechokchai
    Citation: SpringerPlus 2015 4:618
  13. The practical utilization of available modern as well as traditional weather forecasting systems builds herders’ resiliency capacity to climatic shocks. The precision and reliability of the forecasting system ...

    Authors: Desalegn Yayeh Ayal, Solomon Desta, Getachew Gebru, James Kinyangi, John Recha and Maren Radeny
    Citation: SpringerPlus 2015 4:617
  14. Recent developments in molecular cytogenetics allow the detection of genomic rearrangements at an unprecedented level leading to discoveries of previously unknown chromosomal imbalances (zygotic and post-zygot...

    Authors: Ivan Y. Iourov, Svetlana G. Vorsanova, Irina A. Demidova, Galina A. Aliamovskaia, Elena S. Keshishian and Yuri B. Yurov
    Citation: SpringerPlus 2015 4:616
  15. Less developed countries (LDCs) are struggling with an increasing burden of breast cancer. It is important to identify what interventions might be most effective and feasible in reducing overall breast cancer ...

    Authors: JunJie Li and ZhiMin Shao
    Citation: SpringerPlus 2015 4:615
  16. Orthopaedic implant infections are treated by surgical debridement, systematic antibiotic treatment or local antibiotic treatment with antibiotic-loaded beads. Currently antibiotic concentrations in wound exud...

    Authors: Jim C. E. Odekerken, Dorien M. W. Logister, Loubna Assabre, Jacobus J. C. Arts, Geert H. I. M. Walenkamp and Tim J. M. Welting
    Citation: SpringerPlus 2015 4:614
  17. This paper explores the differentials in youth development patterns determined by the economic condition of the household in India. The wealth index is used to glean youth development differentials in the diff...

    Authors: Bijaya Kumar Malik
    Citation: SpringerPlus 2015 4:613
  18. Monitoring the use of antibiotics is relevant due to the public health impact of microbial resistance, adverse effects, and costs. We present data on the consumption of macrolides, lincosamides, streptogramins...

    Authors: Pili Ferrer, Mònica Sabaté, Elena Ballarín, Joan Fortuny, Marietta Rottenkolber, Sven Schmiedl, Joan-Ramon Laporte and Luisa Ibáñez
    Citation: SpringerPlus 2015 4:612
  19. With substantial numbers of breast tumors showing or acquiring treatment resistance, it is of utmost importance to develop new agents for the treatment of the disease, to know their effectiveness against breas...

    Authors: Katharina Uhr, Wendy J. C. Prager-van der Smissen, Anouk A. J. Heine, Bahar Ozturk, Marcel Smid, Hinrich W. H. Göhlmann, Agnes Jager, John A. Foekens and John W. M. Martens
    Citation: SpringerPlus 2015 4:611
  20. Chemokines, including chemokine (C-X-C motif) ligand 1 (CXCL1), regulate tumor epithelial-stromal interactions that facilitate tumor growth and invasion. Recently, several studies have linked CXCL1 expression ...

    Authors: Andre Burnier, Yoshiko Shimizu, Yunfeng Dai, Masakazu Nakashima, Yoshiyuki Matsui, Osamu Ogawa, Charles J. Rosser and Hideki Furuya
    Citation: SpringerPlus 2015 4:610
  21. Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy is a rare hereditary small vessel disease. Ischemic events are the main clinical manifestation of this condition. Here...

    Authors: Daisuke Muta, Takayuki Kawano, Naoki Shinojima and Junichi Kuratsu
    Citation: SpringerPlus 2015 4:609
  22. The aim of this study was to investigate remission and biologic-free remission after orthopaedic surgery and related clinical factors in non-responder to infliximab for rheumatoid arthritis (RA). We analyzed 7...

    Authors: Katsuaki Kanbe, Junji Chiba, Yasuo Inoue, Masashi Taguchi and Akiko Yabuki
    Citation: SpringerPlus 2015 4:607
  23. The purpose of this paper is to report on the development of a mental health stigma reduction toolkit and training, and the acceptability and level of stigma awareness following the stigma-reduction training f...

    Authors: Suzanne L. Hurtado, Cynthia M. Simon-Arndt, Jennifer McAnany and Jenny A. Crain
    Citation: SpringerPlus 2015 4:606
  24. Cervicogenic headaches are a nosologic entity recently recognized. In our common practice, we have noticed a relative frequency of the atlas spina-bifida occulta during the brain CT scan realized for headaches...

    Authors: Amégninou Mawuko Yao Adigo, Lama Kegdigoma Agoda-Kousséma, Ignéza Komi Agbotsou, Kokou Adambounou, Kpalma Duga Bakpatina-Batako, Oni Djagnikpo and Komlanvi Victor Adjénou
    Citation: SpringerPlus 2015 4:605
  25. The transport of live fish is a crucial step to establish fish culture in captivity, and is especially challenging for species that have not been commonly cultured before, therefore transport and handling meth...

    Authors: Ido Bar, Luke Dutney, Peter Lee, Ryosuke Yazawa, Goro Yoshizaki, Yutaka Takeuchi, Scott Cummins and Abigail Elizur
    Citation: SpringerPlus 2015 4:604
  26. Several case-control studies have reported that patients with diabetes mellitus (DM) had a higher prevalence of Helicobacter pylori infection than those without DM, but these findings remain equivocal. Additional...

    Authors: Takashi Tamura, Emi Morita, Sayo Kawai, Tae Sasakabe, Yuka Sugimoto, Nana Fukuda, Shino Suma, Hiroko Nakagawa, Rieko Okada, Asahi Hishida, Mariko Naito, Nobuyuki Hamajima and Kenji Wakai
    Citation: SpringerPlus 2015 4:602
  27. The sialic acid specific humoral lectin, Pjlec of the freshwater crab Paratelphusa jacquemontii was investigated for its opsonin function with rabbit erythrocyte as target cell for phagocytosis by the crab’s hemo...

    Authors: Maghil Denis, Karthigayani Thayappan, Sivakumar Mullivanam Ramasamy and Arumugam Munusamy
    Citation: SpringerPlus 2015 4:601
  28. This study aimed to analyse and compare the stability of two dental posts cemented with four different luting agents by examining their shear stress transfer through the FEM. Eight three-dimensional finite ele...

    Authors: Ahmed A. Madfa, Mohsen A. Al-Hamzi, Fadhel A. Al-Sanabani, Nasr H. Al-Qudaimi and Xiao-Guang Yue
    Citation: SpringerPlus 2015 4:598
  29. Ineffective therapeutic treatments and inadequate repair ability in the central nervous system are disturbing problems for several neurological diseases. Fortunately, the development of clinically applicable p...

    Authors: Mu-Hui Fu, Chia-Ling Li, Hsiu-Lien Lin, Pei-Chun Chen, Marcus J. Calkins, Yu-Fan Chang, Pei-Hsun Cheng and Shang-Hsun Yang
    Citation: SpringerPlus 2015 4:597
  30. The increase in the prevalence of obesity and gastroesophageal reflux disease (GERD) has paralleled one another. Laparoscopic fundoplication (LF) (Nissen or Toupet) is a minimally invasive form of anti-reflux ...

    Authors: Hinali Zaveri, Amit Surve, Daniel Cottam, Christina Richards, Walter Medlin, LeGrand Belnap, Samuel Cottam and Austin Cottam
    Citation: SpringerPlus 2015 4:596
  31. The adoption and adaptation of enclosures in the arid and semi-arid rangelands of sub-Saharan Africa is driven and sustained by a combination of factors. However, reviews indicate that these factors cannot be ...

    Authors: John N. Wairore, Stephen M. Mureithi, Oliver V. Wasonga and Gert Nyberg
    Citation: SpringerPlus 2015 4:595
  32. Observational studies have linked hypocalcemia with adverse clinical outcome in critically ill patients. However, calcium supplementation has never been formally investigated for its beneficial effect in criti...

    Authors: Zhongheng Zhang, Kun Chen and Hongying Ni
    Citation: SpringerPlus 2015 4:594
  33. Much research has been conducted to study the association between personality and eating disorders using clinical samples. However, less research has been done on personality variables in non-clinical cases of...

    Authors: Francesca Cuzzocrea, Sebastiano Costa, Rosalba Larcan and Mary Ellen Toffle
    Citation: SpringerPlus 2015 4:593
  34. This work presents the dynamic graph cut based Otsu’s method to segment the masses in mammogram images. Major concern that threatens human life is cancer. Breast cancer is the most common type of disease among...

    Authors: S. Pitchumani Angayarkanni, Nadira Banu Kamal and Ranjit Jeba Thangaiya
    Citation: SpringerPlus 2015 4:591
  35. This paper presents the results of research regarding the environmental performances of Italian farms with agritourism compared with farms without agritourism. In Italy, agritourism is considered an agricultur...

    Authors: Luigi Mastronardi, Vincenzo Giaccio, Agostino Giannelli and Alfonso Scardera
    Citation: SpringerPlus 2015 4:590
  36. Chronic migraine affects 2 % of the population and has substantial impact on quality of life and considerable burden on healthcare resources. 50–80 % patients with chronic migraine have excessive consumption o...

    Authors: Fayyaz Ahmed, Hassan W. Zafar, Alina Buture and Modar Khalil
    Citation: SpringerPlus 2015 4:589
  37. 2-amino pyridine derivatives have attracted considerable interest because they are useful precursors for the synthesis of a variety of heterocyclic compounds possessing a medicinal value. In this work we aim t...

    Authors: Jamelah S. Al-Otaibi
    Citation: SpringerPlus 2015 4:586
  38. Fatigue is a vague but common complaint that is poorly characterized by physicians as well as patients. While fatigue may result from a number of different etiologies, at the present time, a comprehensive appr...

    Authors: Kevin Johnson and Maryam Sattari
    Citation: SpringerPlus 2015 4:584
  39. The Larsemann Hills is an ice-free area of approximately 50 km2, located halfway between the Vestfold Hills and the Amery Ice Shelf on the south-eastern coast of Prydz Bay, Princess Elizabeth Land, East Antarcti...

    Authors: Abhishek Chauhan, Pawan K. Bharti, Pankaj Goyal, Ajit Varma and Tanu Jindal
    Citation: SpringerPlus 2015 4:582