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  1. Pica and Tuberous sclerosis complex (TSC) are rare disorders. We carried out a population survey of pica in our TSC patient population.

    Authors: Patrick J Morrison, Tara O’Neill, Rachel Hardy, Charles W Shepherd and Deirdre E Donnelly
    Citation: SpringerPlus 2015 4:51
  2. The plant phenol trans-resveratrol, which is mainly found in grape, displays a wide range of biological effects. A cell suspension culture was developed from calli of grape leaves of Vitis vinifera cv. Negramaro ...

    Authors: Marco Taurino, Ilaria Ingrosso, Leone D’amico, Stefania De Domenico, Isabella Nicoletti, Danilo Corradini, Angelo Santino and Giovanna Giovinazzo
    Citation: SpringerPlus 2015 4:49
  3. This study investigated the perceptions on and adaptations to climate change impacts of 235 pangasius farmers in the Mekong Delta, Vietnam. Data were collected using semi-structured household surveys in six pr...

    Authors: Anh Lam Nguyen, Minh Hoang Truong, Johan AJ Verreth, Rik Leemans, Roel H Bosma and Sena S De Silva
    Citation: SpringerPlus 2015 4:46
  4. “Education for Values and Bioethics” is a project which aims to help the student to build his/her personal ethics. It was addressed to ninth grade students (mean age 14) who frequented public education in all ...

    Authors: Rui Nunes, Ivone Duarte, Cristina Santos and Guilhermina Rego
    Citation: SpringerPlus 2015 4:45
  5. Perinatal transmission of hepatitis B virus (HBV) and its associated immune escape mutants (IEMs), is the major vehicle through which a population of chronically infected people who serve as infectious HBV res...

    Authors: Temitope Oluwasegun Cephas Faleye, Moses Olubusuyi Adewumi, Ijeoma Maryjoy Ifeorah, Ewean Chukwuma Omoruyi, Solomon Adeleye Bakarey, Adegboyega Akere, Funmilola Awokunle, Hannah Opeyemi Ajibola, Deborah Oluwaseyi Makanjuola and Johnson Adekunle Adeniji
    Citation: SpringerPlus 2015 4:43
  6. Through history, Arabs and Muslims have made valuable contribution to medicine and science. The main objective of this study was to assess the contribution of Arab researchers to ophthalmology using bibliometr...

    Authors: Waleed M Sweileh, Samah W Al-Jabi, Yousef I Shanti, Ansam F Sawalha and Sa’ed H Zyoud
    Citation: SpringerPlus 2015 4:42
  7. TNF-α inhibitors plus MTX appear to have benefit in the longer-term reduction of RA. Boolean long-term remission under drug-free conditions is rare. The therapeutic mechanism and the factor of predicting respo...

    Authors: Kosaku Oda and Mutsuko Minata
    Citation: SpringerPlus 2015 4:41
  8. The cell-cycle checkpoint kinase 2 (CHEK2) is an important signal transducer of cellular responses to DNA damage, whose defects has been associated with increased risk for breast cancer. The CHEK2 1100delC mut...

    Authors: Chaymaa Marouf, Omar Hajji, Brehima Diakité, Amal Tazzite, Hassan Jouhadi, Abdellatif Benider and Sellama Nadifi
    Citation: SpringerPlus 2015 4:38
  9. Single fraction radiosurgery is conventionally precluded for lesions lying <2-3 mm of the anterior visual pathway because of the radiosensitivity of the optic nerve. We analyzed a series of 64 patients with “p...

    Authors: Alfredo Conti, Antonio Pontoriero, Federica Midili, Giuseppe Iatì, Carmelo Siragusa, Chiara Tomasello, Domenico La Torre, Salvatore M Cardali, Stefano Pergolizzi and Costantino De Renzis
    Citation: SpringerPlus 2015 4:37
  10. Clinicians have traditionally used clinicopathological (CP) factors to determine locoregional recurrence (LR) risk of breast cancer and have generated the IBTR! nomogram to predict the risk of ipsilateral brea...

    Authors: Nikhil G Thaker, Karen E Hoffman, Michael C Stauder, Simona F Shaitelman, Eric A Strom, Welela Tereffe, Benjamin D Smith, George H Perkins, Lei Huo, Mark F Munsell, Lajos Pusztai, Thomas A Buchholz and Wendy A Woodward
    Citation: SpringerPlus 2015 4:36
  11. This study aims to find the genotoxic and cytotoxic effects of a particular combination of pemetrexed (PMX) and cefixime (CFX) in human peripheral blood lymphocytes. Chromosome aberration (CA), sister chromati...

    Authors: Erman Salih Istifli and Mehmet Topaktaş
    Citation: SpringerPlus 2015 4:35
  12. Hyperemesis gravidarum (HG) is a condition characterized by severe, intractable nausea and vomiting in early pregnancy. It affects about 0.3–2% of all pregnancies and is thought that HG is a multifactorial dis...

    Authors: Hüseyin Aksoy, Ülkü Aksoy, Özge İdem Karadağ, Yunus Hacimusalar, Gökhan Açmaz, Gülsüm Aykut, Fulya Çağlı, Burak Yücel, Turgut Aydın and Mustafa Alparslan Babayiğit
    Citation: SpringerPlus 2015 4:34
  13. Statistical tables are an essential component of scientific papers and reports in biomedical and agricultural sciences. Measurements in these tables are summarized as mean ± SEM for each treatment group. Resul...

    Authors: Houssein I Assaad, Yongqing Hou, Lan Zhou, Raymond J Carroll and Guoyao Wu
    Citation: SpringerPlus 2015 4:33
  14. Doxorubicin (DOX) chemotherapy can cause cardiac complications. Angiotensin converting enzyme inhibitors (ACEI) may protect against these complications. We performed a pharmacokinetics (PK) study to determine ...

    Authors: Anne Blaes, Daniel Duprez, Todd Defor, Ryan Shanley, Heather Beckwith, Tufia Haddad, David Potter, Douglas Yee, Kinjal Sanghavi and Pamala Jacobson
    Citation: SpringerPlus 2015 4:32
  15. The physiological and molecular responses of five strains of Streptomyces sp. (CAI-17, CAI-68, CAI-78, KAI-26 and KAI-27), with their proven potential for charcoal rot disease control in sorghum and plant growth-...

    Authors: Subramaniam Gopalakrishnan, Vadlamudi Srinivas, Gottumukkala Alekhya, Bandikinda Prakash, Himabindu Kudapa, Abhishek Rathore and Rajeev Kumar Varshney
    Citation: SpringerPlus 2015 4:31
  16. The aim of this paper is to identify areas of potential improvement of the European Reference Life Cycle Database (ELCD) electricity datasets. The revision is based on the data quality indicators described by ...

    Authors: Daniel Garraín, Simone Fazio, Cristina de la Rúa, Marco Recchioni, Yolanda Lechón and Fabrice Mathieux
    Citation: SpringerPlus 2015 4:30
  17. Dapsone is a commonly used second line drug for prophylaxis of pneumocystis jirovecii pneumonia (PJP) in immunocompromised patients. Oxidant hemolysis, caused by dapsone’s metabolite hydroxylamine, is a common...

    Authors: Scott M Lee and Duvuru Geetha
    Citation: SpringerPlus 2015 4:29
  18. Demyelinating plaques may induce headache through disruption of the pathways, which are implicated in the pathogeneses of migraine. We report a case of 25-year-old female patient, who presented with status mig...

    Authors: Raed Alroughani, Samar F Ahmed, Riyadh Khan and Jasem Al-Hashel
    Citation: SpringerPlus 2015 4:28
  19. Invasive breast carcinoma is the most common cancer in women as in non-ovariectomised pet dogs, which are already identified as a valuable spontaneous preclinical model for that disease. Geographical and time ...

    Authors: Sabine Sévère, Philippe Marchand, Ingrid Guiffard, Floriane Morio, Anaïs Venisseau, Bruno Veyrand, Bruno Le Bizec, Jean-Philippe Antignac and Jérôme Abadie
    Citation: SpringerPlus 2015 4:27
  20. Traumatic brain injury is an injury to the brain parenchyma resulting from external factors such as vehicular accidents, falls, or sports injuries. Its outcome involves primary insult followed by a cascade of ...

    Authors: Alok Sharma, Hemangi Sane, Pooja Kulkarni, Jayanti Yadav, Nandini Gokulchandran, Hema Biju and Prerna Badhe
    Citation: SpringerPlus 2015 4:26
  21. Considerable debate exists about the optimal treatment of ductal carcinoma in situ (DCIS). Using electronic data sources, we examined first course treatment patterns among women aged 18 years and older diagnosed ...

    Authors: Heather Spencer Feigelson, Nikki M Carroll, Sheila Weinmann, Reina Haque, Chu-Ling Yu, Melissa G Butler, Beth Waitzfelder, Michelle G Wrenn, Angela Capra, Elizabeth A McGlynn and Laurel A Habel
    Citation: SpringerPlus 2015 4:24
  22. The Ataxia-telangiectasia mutated (ATM) gene encodes a multifunctional kinase, which is linked to important cellular functions. Women heterozygous for ATM mutations have an estimated relative risk of developing b...

    Authors: Flavia Rotea Mangone, Elisabete C Miracca, Harriet E Feilotter, Lois M Mulligan and Maria Aparecida Nagai
    Citation: SpringerPlus 2015 4:23
  23. Preimplantation genetic diagnosis and/or screening (PGD/PGS) allow the assessment of the genetic health of an embryo before transferring it into the uterus. These techniques require the removal of cellular mat...

    Authors: Ermanno Greco, Anil Biricik, Rocio P Cotarelo, Elisabetta Iammarone, Patrizia Rubino, Jan Tesarik, Francesco Fiorentino and Maria Giulia Minasi
    Citation: SpringerPlus 2015 4:22
  24. Retroperitoneal lymph node dissection (RPLND) is a prognostic, palliative, and potentially therapeutic procedure for patients with malignant phenotype Leydig cell tumours of the testis. We reviewed the records...

    Authors: Jane Hendry, Sioban Fraser, Jeff White, Prabhakar Rajan and David S Hendry
    Citation: SpringerPlus 2015 4:20
  25. Medulloblastoma (MB) comprises four molecularly and genetically distinct subgroups of embryonal brain tumors that develop in the cerebellum. MB mostly affects infants and children and is difficult to treat bec...

    Authors: Karthiga Santhana Kumar, Dimitra Tripolitsioti, Min Ma, Jasmin Grählert, Katja B Egli, Giulio Fiaschetti, Tarek Shalaby, Michael A Grotzer and Martin Baumgartner
    Citation: SpringerPlus 2015 4:19
  26. Marine sponges are a potential source of new molecules with diverse biological activities. We have previously isolated a sphingosine derivative, (9Z)-2-amino-docos-9-ene-1,3,13,14-tetraol (Haliscosamine) from ...

    Authors: Belakssem El Amraoui, Jean François Biard, Fatima Ez-Zohra Ikbal, Majida El Wahidi, Mostafa Kandil, Mohammed El Amraoui and Aziz Fassouane
    Citation: SpringerPlus 2015 4:16
  27. Dietary management which is considered to be one of the cornerstones of diabetes care is based on the principle of healthy eating in the context of social, cultural and psychological influences on food choice....

    Authors: Amelmal Worku, Solomon Mekonnen Abebe and Molla Mesele Wassie
    Citation: SpringerPlus 2015 4:15
  28. Ultrasonography (US) is a valuable tool for confirming the diagnosis of carpal tunnel syndrome (CTS) as it enables the detection of changes in the median nerve shape and rule out anatomic variants as well as s...

    Authors: Yasser El Miedany, Maha El Gaafary, Sally Youssef, Ihab Ahmed and Annie Nasr
    Citation: SpringerPlus 2015 4:13
  29. To determine whether capecitabine (X), combined with docetaxel (T) following doxorubicin (A) and cyclophosphamide (C), enhanced the pathological complete response (pCR) in the breast and axillary lymph nodes (...

    Authors: Jennifer Eremin, Ged Cowley, Leslie G Walker, Elisabeth Murray, Monika Stovickova and Oleg Eremin
    Citation: SpringerPlus 2015 4:9
  30. The objective of the present study was to isolate the biosurfactant (BS) producing lactic acid bacteria (LAB) from traditional fermented food (buttermilk) and its functional and structural characterization. BS...

    Authors: Deepansh Sharma, Baljeet Singh Saharan, Nikhil Chauhan, Suresh Procha and Sohan Lal
    Citation: SpringerPlus 2015 4:4
  31. Both ventricular and parenchymal devices are available for measurement of intracranial pressure (ICP). The Hummingbird® Synergy Ventricular System is a novel device allowing multi-parametric neurological monitori...

    Authors: Tracey Berlin, Cristina Murray-Krezan and Howard Yonas
    Citation: SpringerPlus 2015 4:10
  32. Weaver ants (Oecophylla longinoda Latreille) are used commercially to control pest insects and for protein production. In this respect fast colony growth is desirable for managed colonies. Transplantation of non-...

    Authors: Issa Ouagoussounon, Joachim Offenberg, Antonio Sinzogan, Appolinaire Adandonon, Dansou Kossou and Jean-François Vayssières
    Citation: SpringerPlus 2015 4:6
  33. Multiple osteonecrotic foci can be clinically silent when located in metaphyses and becomes painful when it affects juxta-articular areas. The purpose of this study was to assess the value of fast MR imaging t...

    Authors: Aristidis H Zibis, Sokratis E Varitimidis, Zoe H Dailiana, Apostolos H Karantanas, Dimitrios L Arvanitis and Konstantinos N Malizos
    Citation: SpringerPlus 2015 4:3
  34. We compared the performance of the 3D-Gene® mutation assay (3D-Gene® KRAS mutation assay kit) with the Scorpion-ARMS (therascreen® KRAS RGQ PCR Kit) and Luminex (MEBGEN™ KRAS kit) assays for the detection of KRAS

    Authors: Kazuko Sakai, Azusa Yoneshige, Akihiko Ito, Yoji Ueda, Satoshi Kondo, Hitoshi Nobumasa, Yoshihiko Fujita, Yosuke Togashi, Masato Terashima, Marco A De Velasco, Shuta Tomida and Kazuto Nishio
    Citation: SpringerPlus 2015 4:7
  35. Genetics of micronutrients and their relationships with grain yield and other traits have a direct bearing on devising effective strategies for breeding biofortified crop cultivars. A line × tester study of 19...

    Authors: Anand Kanatti, Kedar N Rai, Kommineni Radhika, Mahalingam Govindaraj, Kanwar L Sahrawat and Aluri S Rao
    Citation: SpringerPlus 2014 3:763
  36. No previous studies have examined marital status of patients with epilepsy and epilepsy-related factors on perceived and enacted stigmas in Iran. In the present study, marital status of patients with epilepsy ...

    Authors: Hamidreza Riasi, Ali Rajabpour Sanati and Kazem Ghaemi
    Citation: SpringerPlus 2014 3:762