Scaling analysis for electrospinning
- Siddharth B Gadkari^{1}Email author
Received: 29 June 2014
Accepted: 13 October 2014
Published: 2 December 2014
Abstract
Electrospinning refers to the process of generating nanofibers from electrified viscous polymeric jets. Though relatively easy to perform, this process is quite complex in its nature, given the large number of parameters that are involved. This study attempts to derive a relation between the final fiber diameter and the major process parameters. Two new dimensionless numbers describing viscous and surface charge repulsion effects are identified from the scaling analysis of governing equation for the motion of a bent jet. Experimental data for a wide range of polymer solutions exhibit a common slope, when expressed in terms of these new dimensionless numbers. This correlation is used to derive a new scaling expression for the final fiber diameter.
Keywords
Electrospinning Scaling analysis CorrelationIntroduction
Electrospinning is a simple and versatile method for producing polymeric nanofibers. When high voltage, of the order of kilovolts, is applied between a capillary (or a syringe needle tip) containing polymer solution and a grounded collector, the hemispherical drop at the tip of the needle undergoes transformation into a conical shape, known as the ‘Taylor cone’. On increasing the voltage further, an electrified thin fluid jet is ejected from the tip of the Taylor cone. The jet is initiated once the electrical forces overcome the surface tension, viscoelastic forces, and the interfacial drawing forces from the inner wall of the capillary (Reneker et al. 2000; Yu et al. 2013). This jet follows a straight path for a certain distance but soon succumbs to numerous electrohydrodynamic instabilities. The most dominant among these is the whipping instability which results in rapid chaotic movement of the jet in concentric circles of increasing diameter. This motion results in extensive elongation and causes extreme thinning of the jet. As the jet moves down, it dries & solidifies and gets deposited on the collector (Hohman et al. 2001).
While electrospinning is quite a simple process to perform, the properties of the final fiber depend on a multitude of molecular, process, and operational parameters. It involves a complex interplay between fluid dynamics, electrodynamics and rheology. Given this complexity, it is difficult to derive a mathematical model for the complete process. In fact most of the current models available are either limited to the steady jet region or are too complex for numerical solutions (Feng 2002; Hohman et al. 2001; Reneker et al. 2000). Although the double/triple-fluid electrospinning processes are broadly reported in literature (Han and Steckl 2009; McCann et al. 2006; Yarin 2011; Yu et al. 2011; Zhang et al. 2004), the complete mechanism about a single-fluid electrospinning process is still not clear.
Simple expressions that could relate the process parameters to the final fiber properties could be great help in analysing the electrospinning process. Such a predictive tool will help to verify and understand many different polymer-solvent systems and guide the experimental studies. There are some correlations reported in literature to foresee a priori the properties of the final electrospun fibers, given the operating parameters and starting solution properties (Fridrikh et al. 2003; Helgeson and Wagner 2007; Helgeson et al. 2008). However each one of these correlations have their own limitations and are mostly limited to selective polymer-solvent systems.
In this study, an attempt to find a relation between final fiber diameter and the important process parameters has been made. The paper is organized as follows, first a literature review on various correlations is presented, followed by the asymptotic analysis and finally the correlation between the two new dimensionless numbers is presented.
Experimental observations
Many researchers have performed detailed investigations to study the effect of the several key parameters on the diameter of electrospun fibers (Beachley and Wen 2009; Cui et al. 2007; Deitzel et al. 2001; Greiner and Wendorff 2008). From experimental investigations reported in literature, solution viscosity, flow rate and applied voltage can be considered as the three most important parameters affecting the final fiber diameter and morphology. Some other parameters such as tip-to-collector distance, solution conductivity and surface tension, have relatively less influence (Ramakrishna et al. 2005).
There is a general agreement in literature that the solution viscosity and applied flow rate are directly proportional to the final fiber diameter d_{ f }, i.e. d_{ f } increases with increase in zero shear rate viscosity η_{0} and applied flow rate Q. In some studies the authors have also reported the scaling coefficient. For example, the scaling coefficient for viscosity has been shown to shown to vary in the range of 0.4–0.7 (Gupta et al. 2005; McKee et al. 2004; Wang et al. 2008).
While there are many studies which reported that d_{ f } increases with increasing flow rate, only few of them have shown systematic data which gives scaling coefficient between the two. Experimental data provided by Wang et al. (2008), Liu et al. (2007) and Mataram et al. (2011) was used to extract the scaling coefficient for Q as 0.3, 0.34 and 0.35 respectively.
The relation between applied voltage △V and fiber diameter is ambiguous. Even though majority of the studies have found that the fiber diameter decreases with increasing voltage (Homayoni et al. 2009; Liu et al. 2007; Mataram et al. 2011; Mazoochi and Jabbari 2011; Sajeev et al. 2008; Thompson et al. 2007; Wang et al. 2009; Yuan et al. 2004; Zhang et al. 2005), there are some experimental studies which have observed an inverse relation (Jeun et al. 2007; Rojas et al. 2009). There are some other studies which have reported a dual effect of applied voltage, in which either the fiber diameter first decreases with increasing voltage up to a threshold value and then increases with further increase in voltage (Supaphol and Chuangchote 2008; Wannatong et al. 2004) or vice-versa (Singh et al. 2009). This ambiguous relation between d_{ f } and △V is probably because △V is interconnected with tip-to-collector distance L, as their ratio (△V/L) determines the applied electric field on the jet. The increase in applied electric field (△V/L) can increase the drawing forces for finer nanofibers, but meanwhile it also promote the faster evaporation of solvents and solidification of nanofibers to let the electrical forces lose efficacy. Similarly many other parameters such as solution concentration and conductivity also influence the overall effect of the applied voltage or the electric field on fiber diameter (Mohan 2002; Thompson et al. 2007). These interlinks with other parameters make it difficult to analyze the individual effect of applied voltage.
There are very few studies where effect of conductivity K and surface tension γ has been investigated independently. Zhang et al. (2005) observed a decrease in fiber diameter with increase in conductivity of the polymer solution whereas Kim et al. (2005) and Mituppatham et al. (2004) reported a reverse trend.
The experimental observations discussed above present the immense complexity of the electrospinning process. The final fiber properties not only depend on a large number of parameters, the scaling with each parameter also depends on the type of polymer-solvent system used. All these factors present a significant challenge to derive one universal correlation for the fiber diameter. Some of the correlations proposed so far, are discussed in the next section.
Existing empirical and semi-empirical correlations
Fridrikh et al. (2003) presented a model of a charged Newtonian fluid jet in an electric field under conditions applicable to whipping instability. The model predicts that the final diameter of the jet arises from a balance between surface charge repulsion and surface tension forces. Here they have used the equation of motion for normal displacements X of the centerline of a bent jet, based on force and angular momentum balance, derived previously by Hohman et al. (2001).
where, γ is the surface tension, $\overline{\epsilon}$ is the dielectric permittivity of atmosphere and I is the total current.
Using the above expression for terminal diameter, Fridrikh et al. (2003) compared experimental data for dry fiber diameters obtained using polycaprolactone (PCL), polyethylene oxide (PEO) and polyacrylonitrile (PAN) polymer solutions with the theoretically predicted values. Quantitative agreement between observed and predicted fiber diameters, however, was found in some, but not all cases. PAN and PEO data showed good agreement, but the model over-predicted stretching for PCL. Fridrikh et al. (2003) attributed the difference in charge carriers and solvent to explain the discrepancy in the agreements. It should be noted that Eq. (1) does not account for solution viscosity, polymer contribution and solvent evaporation. This leads to an inconsistently large role being attributed to surface tension, which based on experimental observations is one of the least important factor in determining fiber diameter.
Helgeson and Wagner (2007) derived an empirical correlation for fiber diameter using two new dimensionless numbers obtained by combining existing non-dimensional numbers that were previously defined by Feng (2002) in his analysis of steady state electrospinning jet. The two new dimensionless numbers were, ${\Pi}_{1}=2{\overline{\epsilon}}^{2}{E}_{0}^{2}/K{\eta}_{0}$, representing the strength of electrostatic stress relative to electro-viscous stress and Π_{2}=(ρ γ R_{ jet })/η_{0}=O h^{−2}, representing the ratio of inertial to viscous forces. Here ρ is the density of the polymer solution, E_{0} is the applied electric field and R_{ jet } represents wet radius of the electrospinning jet, and R_{ jet }=h_{ t }/2.
Helgeson and Wagner (2007) found that values of Π_{1} and Oh from several data sets for different polymer-solvent systems when plotted on one plot reduced onto a single master curve. Two empirical trends were observed in the master plot, first at large Oh where an inverse relationship was observed, such that $\mathit{\text{Oh}}\propto {\Pi}_{1}^{-1}$, and the other regime at smaller values of Oh, where the scaling shifted to −3/4 slope from −1.
Helgeson and Wagner (2007) proposed that by using Eq. (2), it is possible to get an estimate of the final fiber diameter only based on surface tension, solution conductivity, density and applied electric field values. As E_{0} was defined as, E_{0}=△V/L, this model predicts an increase in fiber radius with increasing applied voltage (△V). While there are some experimental studies which predict a increase in final fiber diameter with △V (Jeun et al. 2007; Rojas et al. 2009), there are several other studies which predict an inverse scaling between the two (Liu et al. 2007; Sajeev et al. 2008; Thompson et al. 2007; Wang et al. 2009; Zhang et al. 2005).
using asymptotic analysis in the jet stretching regime.
Here, ε represents the permittivity of the electrospinning fluid, ${\eta}_{e,\infty}^{+}$ is the steady state extensional viscosity, r_{ f } represents the radius of the final electrospun fiber. r_{ f } and R_{ jet } are related as, R_{ jet }=r_{ f }∗(c)^{−0.5}. c is the polymer solution concentration.
While calculating the value of Π_{ f }, in place of ${\eta}_{e,\infty}^{+}$, Helgeson et al. (2008) have used 3η_{0}. This results in the following scaling for viscosity, ${R}_{f}\propto {\eta}_{0}^{-1/7}$. This scaling does not agree with any of the given correlations in literature. Also, Eq. (4) has been shown to be valid only for PEO-water solution, and for no other polymer-solvent system. For PEO-NaCl-water system, there exists a different scaling, namely $O{h}_{f}\propto {\Pi}_{f}^{-1/4}$, which was attributed to the influence of bending instability. This suggests that scaling predicted by Helgeson et al. (2008) between fiber diameter and process parameters is not universal and thus may not be very useful for different polymer-solvent systems.
After reviewing all the above correlations, it can be concluded that, even though progress has been occasionally achieved in some specific cases, research is still far from one universal correlation for predicting the final electrospun fiber diameter. This is probably due to the poor understanding of the complex whipping instability region and the number of inter-related variable interactions occurring during the electrospinning process.
Scaling analysis
Hohman et al. (2001) proposed the equation of motion for the normal displacements of the centerline of the bent jet, which is observed at the onset of whipping. The full equation is quite complicated and involves many variables that are difficult to measure. Usually when flow problems are too complex for analytical or numerical solution, it is a standard engineering practice to non-dimensionalize the governing equations and the non-dimensional numbers thus obtained are then used to guide experimental data correlations.
Hohman et al. (2001) non-dimensionalized the electrohydrodynamic governing equations valid for the jet region of electrospinning before whipping starts, using the following scaling, radius of the capillary or the needle tip r_{ c } for both jet radius h and z, ${t}_{0}=\sqrt{\rho {r}_{c}^{3}/\gamma}$ for time, ${E}_{0}=\sqrt{\gamma /[\phantom{\rule{0.3em}{0ex}}\epsilon -\stackrel{\u0304}{\epsilon}]{r}_{c}}$ for electric field and ${\sigma}_{0}=\sqrt{\gamma \stackrel{\u0304}{\epsilon}/{r}_{c}}$ for surface charge density.
The diameter of the jet at the onset of whipping or in the terminal steady jet regime is about 3−4 orders of magnitude less than the nozzle radius, thus it is not appropriate to continue using the same scaling for the jet radius. In this study, a revised scaling for the non-dimensionalization of the equation for bent jet is proposed and the new dimensionless numbers obtained are examined.
Asymptotic analysis
where, v is the fluid velocity parallel to the jet and prime indicates derivatives with respect to z. Feng (2002) used the following scaling for non-dimensionalisation of the above governing equations: r_{ c } for both h and z, ${v}_{0}=Q/\pi \phantom{\rule{0.3em}{0ex}}{r}_{c}^{2}$ for velocity, ${E}_{0}=I/\phantom{\rule{0.3em}{0ex}}\left(\pi \phantom{\rule{0.3em}{0ex}}{r}_{c}^{2}\phantom{\rule{0.3em}{0ex}}K\right)$ for electric field and ${\sigma}_{0}=\stackrel{\u0304}{\epsilon}{E}_{0}$ for surface charge density.
The above expression correctly predicts the radius of the jet in the terminal region of the steady jet. Similar scaling expression (h∝z^{−1/4}) has been previously derived by Kirichenko et al. (1986) for an inviscid jet.
Revised scaling
However in the whipping region, scaling for h and z cannot be same anymore because z is about 3−4 orders of magnitude more than R_{ om }. L, the total distance between needle tip and collector as the new characteristic scale for z.
Also, the previous scaling for electric field $\left({E}_{0}=I/\phantom{\rule{0.3em}{0ex}}\left(\pi \phantom{\rule{0.3em}{0ex}}{r}_{c}^{2}\phantom{\rule{0.3em}{0ex}}K\right)\right)$ is no longer suitable and the applied electric field, Δ V/L, is used as the new characteristic scaling for E.
For radius of curvature of whipping (R_{ c }), L is used and the normal displacement of the centerline (X) and arc length of the jet (s) are scaled using r_{ c }. For time t, the viscous time scale τ_{ vis }=6η_{0}L/γ, is used for non-dimensionalisation.
Non-dimensionalisation
Here ρ is the density of the polymer solutions, h radius of the jet, R_{ c } radius of curvature of whipping, s arc length of the jet, σ surface charge density, E electric field, ξ static charge density, γ surface tension, ε fluid dielectric constant, $\stackrel{\u0304}{\epsilon}$ air dielectric constant, $\beta =(\epsilon /\stackrel{\u0304}{\epsilon})-1$, K conductivity, k wavenumber of the instability.
Correlation between dimensionless numbers
Among the ten dimensionless numbers, the only term which inherently involved viscosity was Π_{7}, derived from the viscous moment contribution in A_{3}. As discussed before, experimental observations suggest a strong correlation between final fiber diameter and the viscosity of the pre-cursor polymer solution. The viscous moment in A_{3} helps to stabilize the jet against the destabilizing action of surface charge repulsion (B_{4}). The dimensionless number corresponding to B_{4} was Π_{9}. To understand if these two dimensionless numbers had an influence on the final fiber diameter, Π_{7} was plotted against Π_{9} using experimental data from literature for several different polymer-solvent systems.
Experimental data collected from literature to be used in the analysis
Polymer-solvent system | Cited work | η | K | γ | Δ V | L | Q | d _{ f } |
---|---|---|---|---|---|---|---|---|
( P a s) | ( S/ m) | ( N/ m) | ( K V) | ( c m) | m L/ h r | ( n m) | ||
PS/THF/LiCI O_{4} | Wang et al. (2006) | 0.2–2.5 | 0.00012 | 0.0242 | 10 | 14 | 3 | 2400–7400 |
DNA/PEO/Water | Liu et al. (2007) | 2.5 | 0.064 | 0.042 | 5–20 | 10–25 | 6 | 130–210 |
PA-6/FA | Mit-uppatham et al. (2004) | 1.2–4.6 | 0.04–0.4 | 0.04–0.044 | 21 | 10 | 3 | 90–200 |
PA-6/FA/DCM | Wei et al. (2010) | 0.2–14 | 0.13–0.45 | 0.035–0.045 | 20 | 20 | 0.2 | 80–550 |
PS-U2 | Wang et al. (2011) | 0.025–0.1 | 0.0002–0.0003 | 0.0358 | 5 | 14 | 1 | 200–1000 |
PAN/DMF | Wang et al. (2007) | 0.2–1.5 | 0.0035–0.0046 | 0.0363 | 6 | 7 | 0.3 | 250–550 |
PHB/CF/DMF | Wang et al. (2008) | 0.1–5 | 0.00025 | 0.028 | 10 | 14 | 5–14 | 950–5700 |
PAA-Water | Li and Hsiehg (2005) | 0.03–0.7 | 0.002–0.02 | 0.043 | 13.5 | 25 | 1 | 90–550 |
PAA-DMF | Li and Hsiehg (2005) | 0.1–4.0 | 0.00006–0.00007 | 0.038 | 5 | 25 | 1 | 60–330 |
Equation (21) gives the scaling of various factors with d_{ f }. Viscosity, flow rate, conductivity and tip-to-collector distance are directly proportional while applied voltage is inversely proportional to d_{ f }. Qualitatively this scaling matches with the trend observed from experiments for the viscosity, flow rate and applied voltage. Equation (21) predicts a scaling coefficient of 0.5 for both viscosity and flow rate. For viscosity, the predicted scaling coefficient is close to the average scaling predicted from the experimental studies. For flow rate however, the average of the three scaling coefficients obtained from experimental studies is 0.325 (Liu et al. 2007; Mataram et al. 2011; Wang et al. 2008), which is lower than 0.5. For △V, L and K there are very few methodical studies (with experimental data) available in literature to compare the coefficient values.
The force balance for bent jet proposed by Hohman et al. (2001) is only valid for Newtonian solutions. Thus polymer properties such as relaxation time and polymer extensional viscosity are not included in this analysis. There are studies which suggest the significant importance of viscoelastic properties in electrospinning (Thompson et al. 2007; Yu et al. 2006). Polymer molecules are known to undergo coil-stretch transition in extensional flows such as in electrospinning. This leads to an escalation of extensional viscosity of the polymer solution. However it is believed that the polymer extensional viscosity would reach its finite extensibility limit during whipping and thus the polymer solution would behave as a high viscosity Newtonian solution. The ratio of steady state extensional viscosity of the polymer solution to zero shear rate viscosity is termed as the steady state Trouton ratio $T{r}_{\infty}^{+}$. The value of $T{r}_{\infty}^{+}$ for different polymer-solvent systems would be different. Inclusion of these polymer properties could possibly lead to collapse all experimental data on one master curve and help in deriving an universal correlation for final fiber diameter in electrospinning.
It should be noted however, that even with all the shortcomings this crass analysis has the virtue of utter usefulness and ease. Eq. (21) predicts the correct trend for the three most important parameters that affect the electrospinning process, namely viscosity, flow rate and applied voltage. Also the scaling coefficients predicted are fairly close to the experimental studies. As pointed out, more systematic studies need to be carried out to verify the correctness of the scalings predicted and additional physics needs to be added to arrive at a universal correlation between final fiber diameter and the process parameters of electrospinning.
Declarations
Authors’ Affiliations
References
- Beachley V, Wen X: Effect of electrospinning parameters on the nanofiber diameter and length. Mater Sci Eng C Mater Biol Appl 2009, 29: 663-668. 10.1016/j.msec.2008.10.037View ArticleGoogle Scholar
- Bhattacharjee PK, Schneider TM, Brenner MP, McKinley GH, Rutledge GC: On the measured current in electrospinning. J Appl Phys 2010, 107: 044306. 10.1063/1.3277018View ArticleGoogle Scholar
- Cui W, Li X, Zhou S, Weng J: Investigation on process parameters of electrospinning system through orthogonal experimental design. J Appl Polym Sci 2007, 103: 3105-3112. 10.1002/app.25464View ArticleGoogle Scholar
- Deitzel JM, Kleinmeyer J, Harris D, Beck Tan NC: The effect of processing variables on the morphology of electrospun nanofibers and textiles. Polymer 2001, 42: 261-272. 10.1016/S0032-3861(00)00250-0View ArticleGoogle Scholar
- Feng JJ: The stretching of an electrified non-newtonian jet: a model for electrospinning. Phys Fluids 2002, 14(11):3912-3926. 10.1063/1.1510664View ArticleGoogle Scholar
- Fridrikh S, Yu J, Brenner M, Rutledge G: Controlling the fiber diameter during electrospinning. Phys Rev Lett 2003, 90(14):144502.View ArticleGoogle Scholar
- Greiner A, Wendorff JH: Functional self-assembled nanofibers by Electrospinning. Adv Polym Sci 2008, 219: 107-171.Google Scholar
- Gupta P, Elkins C, Long TE, Wilkes GL: Electrospinning of linear homopolymers of poly(methyl methacrylate): exploring relationships between fiber formation, viscosity, molecular weight and concentration in a good solvent. Polymer 2005, 46(13):4799-4810. 10.1016/j.polymer.2005.04.021View ArticleGoogle Scholar
- Han D, Steckl AJ: Superhydrophobic and oleophobic fibers by coaxial electrospinning. Langmuir 2009, 25(16):9454-9462. 10.1021/la900660vView ArticleGoogle Scholar
- Helgeson ME, Wagner NJ: A correlation for the diameter of electrospun polymer nanofibers. AIChE J 2007, 53(1):51-55. 10.1002/aic.11056View ArticleGoogle Scholar
- Helgeson M, Grammatikos K, Deitzel J, Wagner N: Theory and kinematic measurements of the mechanics of stable electrospun polymer jets. Polymer 2008, 49(12):2924-2936. 10.1016/j.polymer.2008.04.025View ArticleGoogle Scholar
- Hohman MM, Shin M, Rutledge G, Brenner MP: Electrospinning and electrically forced jets. I. stability theory. Phys Fluids 2001, 13(8):2201-2220. 10.1063/1.1383791View ArticleGoogle Scholar
- Homayoni H, Ravandi SAH, Valizadeh M: Electrospinning of chitosan nanofibers: Processing optimization. Carbohydr Polymer 2009, 77(3):656-661. 10.1016/j.carbpol.2009.02.008View ArticleGoogle Scholar
- Jeun J-P, Kim Y-H, Lim Y-M, Choi J-H, Jung C-H, Kang P-H, Nho Y-C: Electrospinning of poly(l-lactide-co-d, l-lactide). J Ind Eng Chem 2007, 13(4):592-596.Google Scholar
- Li L, Hsiehg Y-L: Ultra-fine polyelectrolyte fibers from electrospinning of poly(acrylic acid). Polymer 2005, 46: 5133-5139. 10.1016/j.polymer.2005.04.039View ArticleGoogle Scholar
- Liu Y, Chen J, Misoska V, Wallace G: Preparation of novel ultrafine fibers based on DNA and poly(ethylene oxide) by electrospinning from aqueous solutions. React Funct Polym 2007, 67(5):461-467. 10.1016/j.reactfunctpolym.2007.02.008View ArticleGoogle Scholar
- Kim B, Park H, Lee S-H, Sigmund WM: Poly(acrylic acid) nanofibers by electrospinning. Mater Lett 2005, 59(7):829-832. 10.1016/j.matlet.2004.11.032View ArticleGoogle Scholar
- Kirichenko VN, Petryanov-Sokolov IV: Asymptotic radius of a slightly conducting liquid jet in an electric field. Soviet Phys Dokl 1986, 31: 611.Google Scholar
- Mataram A, Ismail AF, Abdullah MS, Ng BC, Matsuura T: A review of assembled polyacrylonitrile-based carbon nanofiber prepared electrospinning process. Int J Nanosci 2011, 10(3):455-469. 10.1142/S0219581X11008228View ArticleGoogle Scholar
- McCann JT, Marquez M, Xia Y: Melt coaxial electrospinning: a versatile method for the encapsulation of solid materials and fabrication of phase change nanofibers. Nano Lett 2006, 6(12):2868-2872. 10.1021/nl0620839View ArticleGoogle Scholar
- McKee MG, Wilkes GL, Colby RH, Long TE: Correlations of solution rheology with electrospun fiber formation of linear and branched polyesters. Macromol 2004, 37(5):1760-1767. 10.1021/ma035689hView ArticleGoogle Scholar
- Mazoochi T, Jabbari V: Chitosan nanofibrous scaffold fabricated via electrospinning: the effect of processing parameters on the nanofiber morphology. Int J Polym Anal Charact 2011, 16(5):277-289. 10.1080/1023666X.2011.587943View ArticleGoogle Scholar
- Mit-uppatham C, Nithitanakul M, Supaphol P: Ultrafine electrospun polyamide-6 fibers: effect of solution conditions on morphology and average fiber diameter. Macromol Chem Phys 2004, 205(17):2327-2338. 10.1002/macp.200400225View ArticleGoogle Scholar
- Mohan A: Formation and characterization of electrospun nonwoven webs. Master’s thesis, North Carolina State University; 2002.Google Scholar
- Ramakrishna S, Fujihara K, Teo W, Lim T, Ma Z: An Introduction to Electrospinning and Nanofibres. World Scientific Publishing Co, Singapore; 2005.View ArticleGoogle Scholar
- Reneker DH, Yarin AL, Fong H: Bending instability of electrically charged liquid jets of polymer solutions in electrospinning. J Appl Phys 2000, 87(9):4531-4547. 10.1063/1.373532View ArticleGoogle Scholar
- Rojas OJ, Montero GA, Habibi Y: Electrospun nanocomposites from polystyrene loaded with cellulose nanowhiskers. J Appl Polym Sci 2009, 113(2):927-935. 10.1002/app.30011View ArticleGoogle Scholar
- Sajeev US, Anand KA, Menon D, Nair S: Control of nanostructures in pva, pva/chitosan blends and pcl through electrospinning. Bull Mater Sci 2008, 31(3):343-351. 10.1007/s12034-008-0054-9View ArticleGoogle Scholar
- Singh S, Lakshmi SG, Vijayakumar M: Effect of process parameters on the microstructural characteristics of electrospun poly(vinyl alcohol) fiber mats. Nanobiotechnology 2009, 5(1–4):10-16.View ArticleGoogle Scholar
- Supaphol P, Chuangchote S: On the electrospinning of poly(vinyl alcohol) nanofiber mats: a revisit. J Appl Polym Sci 2008, 108(2):969-978. 10.1002/app.27664View ArticleGoogle Scholar
- Thompson CJ, Chase GG, Yarin AL, Reneker DH: Effects of parameters on nanofiber diameter determined from electrospinning model. Polymer 2007, 48(23):6913-6922. 10.1016/j.polymer.2007.09.017View ArticleGoogle Scholar
- Wang C, Cheng Y-W, Hsu C-H, Chien H-S, Tsou S-Y: How to manipulate the electrospinning jet with controlled properties to obtain uniform fibers with the smallest diameter?—a brief discussion of solution electrospinning process. J Polym Res 2011, 18: 111-123. 10.1007/s10965-010-9397-1View ArticleGoogle Scholar
- Wang C, Chien H-S, Hsu C-H, Wang Y-C, Wang C-T, Lu H-A: Electrospinning of polyacrylonitrile solutions at elevated temperatures. Macromol 2007, 40(22):7973-7983. 10.1021/ma070508nView ArticleGoogle Scholar
- Wang C, Hsu C-H, Hwang IH: Scaling laws and internal structure for characterizing electrospun poly[(R)-3-hydroxybutyrate] fibers. Polymer 2008, 49(19):4188-4195. 10.1016/j.polymer.2008.07.033View ArticleGoogle Scholar
- Wang C, Hsu C-H, Lin J-H: Scaling laws in electrospinning of polystyrene solutions. Macromol 2006, 39(22):7662-7672. 10.1021/ma060866aView ArticleGoogle Scholar
- Wang C, Yuan J, Niu H, Yan E, Zhao H: Investigation of fundamental parameters affecting electrospun pva/cus composite nanofibres. Pigm Resin Technol 2009, 38(1):25-32. 10.1108/03699420910923544View ArticleGoogle Scholar
- Wannatong L, Sirivat A, Supaphol P: Effects of solvents on electrospun polymeric fibers: preliminary study on polystyrene. Polym Int 2004, 53(11):1851-1859. 10.1002/pi.1599View ArticleGoogle Scholar
- Wei W, Yeh J-T, Li P, Li M-R, Li W, Wang X-L: Effect of nonsolvent on morphologies of polyamide 6 electrospun fibers. J Appl Polym Sci 2010, 118(5):3005-3012. 10.1002/app.32704View ArticleGoogle Scholar
- Yarin AL: Coaxial electrospinning and emulsion electrospinning of core-shell fibers. Polymer Adv Tech 2011, 22(3):310-317. 10.1002/pat.1781View ArticleGoogle Scholar
- Yu D-G, Branford-White C, Bligh SWA, White K, Chatterton NP, Zhu L-M: Improving polymer nanofiber quality using a modified co-axial electrospinning process. Macromol Rapid Comm 2011, 32(9–10):744-750.View ArticleGoogle Scholar
- Yu JH, Fridrikh SV, Rutledge GC: The role of elasticity in the formation of electrospun fibers. Polymer 2006, 47(13):4789-4797. 10.1016/j.polymer.2006.04.050View ArticleGoogle Scholar
- Yu D-G, Williams GR, Wang X, Liu XK, Li HL, Bligh SWA: Coaxial electrospinning using a concentric Teflon spinneret to prepare biphasic-release nanofibers of helicid. RSC Adv 2013, 3(39):17775-17783. 10.1039/c3ra43222jView ArticleGoogle Scholar
- Yuan XY, Zhang YY, Dong C, Sheng J: Morphology of ultrafine polysulfone fibers prepared by electrospinning. Polym Int 2004, 53(11):1704-1710. 10.1002/pi.1538View ArticleGoogle Scholar
- Zhang Y, Huang Z-M, Xu X, Lim CT, Ramakrishna S: Preparation of core-shell structured pcl-r-gelatin bi-component nanofibers by coaxial electrospinning. Chem Mater 2004, 16(18):3406-3409. 10.1021/cm049580fView ArticleGoogle Scholar
- Zhang C, Yuan X, Wu L, Han Y, Sheng J: Study on morphology of electrospun poly(vinyl alcohol) mats. Eur Polym J 2005, 41(3):423-432. 10.1016/j.eurpolymj.2004.10.027View ArticleGoogle Scholar
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