Figure 5From: Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogensThe lowest energy pose of 3-hexadecanoyl 11,12-oxidotaraxerol (yellow) and crassifoate (blue) in the active site of T. cruzi CYP51. The hydrophobic amino acid residues in the active site offer a favorable binding patch for the esterified sterols. The molecular surface diagram is shown in Additional file 1: Figure S3.Back to article page