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Table 2 Correlation between ΔVEGF and ΔbFGF, and OSAS severity

From: Elevation of plasma basic fibroblast growth factor after nocturnal hypoxic events in patients with obstructive sleep apnea syndrome

 

ΔVEGF (pg/ml)

ΔbFGF (pg/ml)

 

rs (P value)

rs (P value)

Age (years)

-0.202 (1.41 × 10-1)

-0.242 (2.04 × 10-1)

BMI (kg/m2)

-0.145 (1.20 × 10-1)

0.218 (2.25 × 10-1)

AHI

0.00962 (2.40 × 10-1)

0.371 (1.17 × 10-2)

SpO2 < 90% (% TST)

0.0716 (1.77 × 10-1)

0.335 (1.88 × 10-2)

4% ODI

0.0126 (2.37 × 10-1)

0.354 (1.48 × 10-2)

Median SpO2 (%)

0.0907 (1.62 × 10-1)

-0.356 (1.69 × 10-2)

Minimal SpO2 (%)

-0.0285 (2.20 × 10-1)

-0.314 (1.92 × 10-2)

  1. Correlations between the overnight changes (before and after PSG) in plasma VEGF and bFGF concentrations (ΔVEGF and ΔbFGF, respectively) and hypoxia-associated parameters of OSAS severity were analyzed by using the Pearson’s correlation coefficient. Coefficients of correlation are represented by rs and statistical probabilities by P values in parentheses.
  2. AHI apnea-hypopnea index, BMI body mass index, bFGF basic fibroblast growth factor, SpO 2  < 90% (% TST) percentage of total sleep time with oxygen saturation below 90%, ODI oxygen desaturation index, SpO 2 oxygen saturation with pulse oximetry, rs Pearson’s coefficient of correlation, VEGF vascular endothelial growth factor.