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Table 1 Summary of subjects and their evaluation parameters

From: Elevation of plasma basic fibroblast growth factor after nocturnal hypoxic events in patients with obstructive sleep apnea syndrome

  

Control

OSAS

P value

Subject (n)

 

17

13

 

Age (years)

 

44.3 ± 11.3

46.1 ± 12.1

6.79 × 10-1

BMI (kg/m2)

 

24.9 ± 2.92

29.9 ± 2.60

6.08 × 10-4

AHI

 

8.03 ± 6.51

50.9 ± 32.5

1.13 × 10-5

SpO2 < 90%

(% TST)

0.681 ± 1.31

17.8 ± 16.5

2.84 × 10-4

4% ODI

 

4.62 ± 4.23

37.1 ± 23.4

4.82 × 10-6

Median SpO2

(%)

96.4 ± 1.45

93.0 ± 3.08

6.21 × 10-4

Minimal SpO2

(%)

86.5 ± 6.72

67.6 ± 10.3

1.60 × 10-6

VEGF (pg/ml)

Night

14.8 ± 1.01

12.5 ± 2.24

1.68 × 10-1

 

Morning

13.0 ± 1.85

10.3 ± 3.09

2.67 × 10-1

bFGF (pg/ml)

Night

2.01 ± 0.831

2.21 ± 0.573

7.47 × 10-1

 

Morning

2.02 ± 0.743

3.43 ± 0.428

7.46 × 10-3

Hb (g/dl)

Night

15.2 ± 0.994

14.9 ± 0.953

6.10 × 10-1

 

Morning

15.4 ± 1.06

15.6 ± 0.875

5.76 × 10-1

  1. All participants were categorized into two groups by their OSAS severity (control, AHI ≤ 15; and OSAS, 15 < AHI). Concentrations of plasma VEGF, bFGF, and Hb the night before PSG and the next morning were measured (night and morning, respectively). Data are presented as mean values ± standard deviations. Statistical analysis for evaluation parameters among the categories was performed by the Student t-test.
  2. AHI apnea-hypopnea index, bFGF basic fibroblast growth factor, BMI body mass index, SpO 2  < 90% (% TST) percentage of total sleep time with oxygen saturation below 90%, Hb hemoglobin, ODI oxygen desaturation index, SpO 2 oxygen saturation with pulse oximetry, VEGF vascular endothelial growth factor.