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  1. Research

    Reliability and validity of the EQ-5D-3L for Kashin–Beck disease in China

    Kashin–Beck Disease (KBD) is an endemic osteoarthropathy in areas which extend from the North-East to the South-West of China. Most of the patients with KBD suffer multiple dysfunctions in major joints causing...

    Hua Fang, Umer Farooq, Dimiao Wang, Fangfang Yu, Mohammad Imran Younus and Xiong Guo

    SpringerPlus 2016 5:1924

    Published on: 7 November 2016

  2. Research

    The burden of metastatic disease of the femur on the Medicare system

    In the United States, over 1,650,000 new cases of cancer are being diagnosed yearly with almost 50 % of them being the top five bone-seeking cancers. Since cancer risk increases with age, this suggests that or...

    Kirollos Gendi, David Hennessy and John Heiner

    SpringerPlus 2016 5:1916

    Published on: 4 November 2016

  3. Research

    Safety of heparin bridging therapy for transrectal ultrasound-guided prostate biopsy in patients requiring temporary discontinuation of antithrombotic agents

    Safety of heparin bridging therapy for transrectal ultrasound-guided prostate (TRUS) biopsy in patients requiring temporary discontinuation of antithrombotic therapy is unknown. This study aimed to assess the ...

    Itsuto Hamano, Shingo Hatakeyama, Tohru Yoneyama, Yuki Tobisawa, Osamu Soma, Teppei Matsumoto, Hayato Yamamoto, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie and Chikara Ohyama

    SpringerPlus 2016 5:1917

    Published on: 4 November 2016

  4. Research

    Comparisons of oncological and functional outcomes among radical retropubic prostatectomy, high dose rate brachytherapy, cryoablation and high-intensity focused ultrasound for localized prostate cancer

    To conduct a retrospective, single institutional and comparative study for radical retropubic prostatectomy (RRP), high dose rate brachytherapy (HDRBT), cryoablation and high-intensity focused ultrasound (HIFU...

    Po Hui Chiang and Yi Yang Liu

    SpringerPlus 2016 5:1905

    Published on: 3 November 2016

  5. Research

    The assessment of myometrium perfusion in patients with uterine fibroid by arterial spin labeling MRI

    It has been suggested that an inadequate blood supply caused by uterine fibroids may lead to decreasing fertility. Therefore, a quantitative evaluation of blood flow in the uterus might be a good tool for infe...

    Nozomi Takahashi, Osamu Yoshino, Osamu Hiraike, Eriko Maeda, Masanobu Nakamura, Masaaki Hori, Miyuki Harada, Kaori Koga, Shigeru Saito, Tomoyuki Fujii and Yutaka Osuga

    SpringerPlus 2016 5:1907

    Published on: 3 November 2016

  6. Research

    Severe ARDS caused by adenovirus: early initiation of ECMO plus continuous renal replacement therapy

    The reported survival rates of patients with acute respiratory distress syndrome (ARDS) caused by human adenovirus (HAdV) pneumonia are poor. The results do not differ much in immunocompetent patients supporte...

    Sang Ook Ha, Hyoung Soo Kim, Sunghoon Park, Ki-Suck Jung, Seung Hun Jang, Sang Jin Han, Hyun-Sook Kim and Sun Hee Lee

    SpringerPlus 2016 5:1909

    Published on: 3 November 2016

  7. Case study

    Dramatic mitigation of bone pain after phosphorus replacement therapy in a subject with FGF23-related hypophosphatemic osteomalacia

    Fibroblast growth factor 23 (FGF23) is secreted from bone and suppresses the absorption of phosphorus in renal proximal tubule and in intestinal tract. Therefore, the increase of serum FGF23 levels leads to hy...

    Fuminori Tatsumi, Megumi Horiya, Akihito Tanabe, Momoyo Nishioka, Yoshiro Fushimi, Junpei Sanada, Yurie Hirata, Shintaro Irie, Tomoe Kinoshita, Shinji Kamei, Masashi Shimoda, Tomoatsu Mune, Kohei Kaku and Hideaki Kaneto

    SpringerPlus 2016 5:1904

    Published on: 2 November 2016

  8. Research

    Fixation of split-thickness skin graft using fast-clotting fibrin glue containing undiluted high-concentration thrombin or sutures: a comparison study

    For skin defects caused by full-thickness burns, trauma, or tumor tissue excision, skin grafting is one of the most convenient and useful treatment methods. In this situation, graft fixation is important in sk...

    Hyun Ho Han, Daiwon Jun, Suk-Ho Moon, In Sook Kang and Min Cheol Kim

    SpringerPlus 2016 5:1902

    Published on: 2 November 2016

  9. Research

    Bibliometric analysis of medicine-related publications on poverty (2005–2015)

    Poverty is a global problem. The war against poverty requires not only financial support, but also poverty-related research to pinpoint areas of high need of intervention. In line with international efforts to...

    Waleed M. Sweileh, Samah W. Al-Jabi, Ansam F. Sawalha, Adham S. AbuTaha and Sa’ed H. Zyoud

    SpringerPlus 2016 5:1888

    Published on: 28 October 2016

  10. Research

    Mortality markers in nosocomial Klebsiella pneumoniae bloodstream infection

    Klebsiella pneumoniae is the most common endogen agent for nosocomial infections. In this study, mortality markers were investigated in patients with nosocomial K. pneumoniae blood str...

    Bulent Durdu, Ismail Necati Hakyemez, Sibel Bolukcu, Gulay Okay, Bilge Gultepe and Turan Aslan

    SpringerPlus 2016 5:1892

    Published on: 28 October 2016

  11. Research

    Urbanization may affect the incidence of urolithiasis in South Korea

    We evaluated the different climatic factors in urban and rural areas that may affect the incidence of urolithiasis. Nationwide data on urolithiasis were acquired from Health Insurance Review and Assessment Ser...

    Se Young Choi, Seo Yeon Lee, Byung Hoon Chi, Jin Wook Kim, Tae-Hyoung Kim and In Ho Chang

    SpringerPlus 2016 5:1891

    Published on: 28 October 2016

  12. Research

    Prognostic significance of platelet–lymphocyte ratio in patients receiving first-line tyrosine kinase inhibitors for metastatic renal cell cancer

    The platelet–lymphocyte ratio (PLR) and neutrophil–lymphocyte ratio (NLR) have been reported as prognostic factors in various cancers, but their roles in metastatic renal cell cancer (mRCC) remain unclear. We ...

    Tae Ju Park, Yang Hyun Cho, Ho Seok Chung, Eu Chang Hwang, Sung-Hoon Jung, Jun Eul Hwang, Woo Kyun Bae, Jin Woong Kim, Suk Hee Heo, Young Hoe Hur, Seung Il Jung and Dong Deuk Kwon

    SpringerPlus 2016 5:1889

    Published on: 28 October 2016

  13. Research

    Permeability and distribution of nerve growth factor in the brain of neonatal rats by periphery venous injection in hypoxic-ischemic state

    To investigate the permeability of β-NGF through blood–brain-barrier (BBB) in neonatal and adult rats, and the spatial distribution of β-NGF in different brain regions in hypoxic-ischemic (HI) and normal neona...

    Wenli Zhou, Jiantao Zhang, Guangming Wang, Limian Ling and Chaoying Yan

    SpringerPlus 2016 5:1893

    Published on: 28 October 2016

  14. Research

    Objective evaluation of oxaliplatin-induced vascular pain secondary to peripheral vein administration

    During oxaliplatin chemotherapy administration via a peripheral vein, vascular pain requires changing of the intravenous infusion route on occasion. Vascular pain induced by anticancer drugs reduces the rate o...

    Yoichiro Yoshida, Ai Mogi, Naoya Aisu, Teppei Yamada, Taisuke Matsuoka, Daibo Kojima, Toshiyuki Mera, Tomoko Koganemaru, Fumiaki Kiyomi, Keita Noda, Yasushi Takamatsu, Kazuo Tamura, Yuichi Yamashita and Suguru Hasegawa

    SpringerPlus 2016 5:1872

    Published on: 26 October 2016

  15. Research

    Patient-reported outcomes of femoral osteotomy and total hip arthroplasty for osteonecrosis of the femoral head: a prospective case series study

    Patient-reported scoring systems have recently been used after surgical procedures. The purpose of this prospective study was to evaluate the patient-reported outcomes of femoral osteotomy and total hip arthro...

    Yusuke Kubo, Takuaki Yamamoto, Goro Motomura, Kazuyuki Karasuyama, Kazuhiko Sonoda and Yukihide Iwamoto

    SpringerPlus 2016 5:1880

    Published on: 26 October 2016

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