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Biomedical and Life Sciences

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  1. In Present work, the main objective is to develop less time consuming protocol for genomic DNA isolation from leaves of Passiflora foetida. Optimized protocol is cost effective, as it avoided use of expensive liq...

    Authors: Bipin Deochand Lade, Anita Surendra Patil and Hariprassad Madhukarrao Paikrao
    Citation: SpringerPlus 2014 3:457
  2. To investigate the effects of L-serine intake on human sleep, we conducted two randomized double-blinded crossover studies. In Study 1, healthy subjects who were dissatisfied with their sleep were given L-seri...

    Authors: Yukihiko Ito, Satomi Takahashi, Manzhen Shen, Kohji Yamaguchi and Makoto Satoh
    Citation: SpringerPlus 2014 3:456
  3. Multiple environmental and genetic factors are involved with the development of basal cell carcinomas (BCC), as well as with breast cancers. Tumor initiation and progression are often associated with genomic i...

    Authors: Alessandra Morelle, Rodrigo Cericatto, Ana Cristina Victorino Krepischi and Itamar Romano Garcia Ruiz
    Citation: SpringerPlus 2014 3:454
  4. Diets for elderly must contain nutritious foods, fit their physiological limitations, and match with their food culture. Cereals and legumes are suggested food choices regardless of their cultures and beliefs....

    Authors: Pruet Satusap, Visith Chavasit, Wantanee Kriengsinyos and Kunchit Judprasong
    Citation: SpringerPlus 2014 3:451
  5. The Medical Malacology Collection (Coleção de Malacologia Médica, Fiocruz-CMM) is a depository of medically relevant mollusks, especially from the genus Biomphalaria, which includes the hosts of Schistosoma manso...

    Authors: Cryslaine Aguiar-Silva, Cristiane Lafetá Furtado Mendonça, Pedro Henrique da Cunha Kellis Pinheiro, Silvia Gonçalves Mesquita, Omar dos Santos Carvalho and Roberta Lima Caldeira
    Citation: SpringerPlus 2014 3:446
  6. The goal of metabolomics data pre-processing is to eliminate systematic variation, such that biologically-related metabolite signatures are detected by statistical pattern recognition. Although several methods...

    Authors: Mingjie Chen, R Shyama Prasad Rao, Yiming Zhang, Cathy Xiaoyan Zhong and Jay J Thelen
    Citation: SpringerPlus 2014 3:439
  7. Melioidosis is an emerging infectious disease caused by a free living soil dwelling Gram-negative bacterium Burkholderia pseudomallei. The disease is endemic to most parts of Southeast Asia and northern Australia...

    Authors: Archana Prakash, Duraipandian Thavaselvam, Ashu Kumar, Ajith Kumar, Sonia Arora, Sapana Tiwari, Anita Barua and Kannusamy Sathyaseelan
    Citation: SpringerPlus 2014 3:438
  8. Understanding structure of the population is one of the major objective of many genetic studies. The program STRUCTURE is commonly used to infer population structure using multi-locus genotype data. However, a...

    Authors: Ramesh Krishnan Ramasamy, Sumathy Ramasamy, Bharat Bushan Bindroo and V Girish Naik
    Citation: SpringerPlus 2014 3:431
  9. The mannanase gene of B. circulans NT 6.7 was cloned and expressed in an Escherichia coli expression system. The B. circulans NT 6.7 mannanase gene consists of 1,083 nucleotides encoding a 360-amino acid residue ...

    Authors: Yotthachai Piwpankaew, Supa Sakulsirirat, Sunee Nitisinprasert, Thu-Ha Nguyen, Dietmar Haltrich and Suttipun Keawsompong
    Citation: SpringerPlus 2014 3:430
  10. The purpose of this study was to determine which suture material is the most appropriate for dermal closure of terrestrial annelids. This paper describes the tissue reactions of the earthworm, Lumbricus terrestri...

    Authors: Melissa A Salgado, Gregory A Lewbart, Larry S Christian, Emily H Griffith and Jerry McHugh Law
    Citation: SpringerPlus 2014 3:423
  11. Winter-flooding of rice paddies without the application of agricultural chemicals is attracting attention as a new agricultural method for enhancing the habitat conditions of wintering waterfowl in rice paddy ...

    Authors: Mayura B Takada, Shun Takagi, Shigeki Iwabuchi, Takuya Mineta and Izumi Washitani
    Citation: SpringerPlus 2014 3:418
  12. The present study aimed to analyze, in Italian children and adolescents, the beliefs about which foods are fattening, the appreciation of fattening foods, and the perception of some socio-cultural attributes o...

    Authors: Stefania Toselli, Patricia Brasili, Rocco Di Michele and Federico Spiga
    Citation: SpringerPlus 2014 3:402
  13. Tylophora indica Burm F. Merrill. is widely used against various diseases owing to the presence an array of medicinally important secondary metabolites. Its stem is bitter, stomachic, stimulates bile secretion, e...

    Authors: Madan Mohan Sharma, Roop Narayan Verma, Abhijeet Singh and Amla Batra
    Citation: SpringerPlus 2014 3:400
  14. The embryo of the maize grain (Zea mays L.) is separated from the starchy endosperm by a fibrous structure, which is called the fibrous layer (FL). Using histochemical staining, it was determined that the FL is c...

    Authors: José Isaac Corona-Carrillo, Mitzi Flores-Ponce, Gerardo Chávez-Nájera and David Manuel Díaz-Pontones
    Citation: SpringerPlus 2014 3:399
  15. Urate oxidase is an important enzyme with therapeutic and diagnostic applications. Rasburicase is a recombinant urate oxidase enzyme approved by FDA to use in the treatment of hyperuricemia conditions. Various...

    Authors: Ramin Fazel, Najmeh Zarei, Nasser Ghaemi, Mohammad Mehdi Namvaran, Somayeh Enayati, Esmat Mirabzadeh Ardakani, Mohammad Azizi and Vahid Khalaj
    Citation: SpringerPlus 2014 3:395
  16. The rhizobacterial communities of 29 pioneer plants belonging to 12 species were investigated in an alpine ecosystem to assess if plants from different species could select for specific rhizobacterial communit...

    Authors: Sonia Ciccazzo, Alfonso Esposito, Eleonora Rolli, Stefan Zerbe, Daniele Daffonchio and Lorenzo Brusetti
    Citation: SpringerPlus 2014 3:391
  17. Chemotherapy-induced nausea and vomiting is ranked among the worst side effects of chemotherapy. NEPA is an oral fixed-dose combination antiemetic under development, consisting of netupitant 300 mg, a highly s...

    Authors: Tulla Spinelli, Cecilia Moresino, Sybille Baumann, Wolfgang Timmer and Armin Schultz
    Citation: SpringerPlus 2014 3:389
  18. Malaria and helminth co infection are common in tropical and subtropical areas where they affect the life of millions of people. While both helminth and malaria parasites have immunomodulatory activities, litt...

    Authors: Ulysse Ateba Ngoa, Jeannot Fréjus Zinsou, Roland Fabrice Kassa Kassa, Eliane Ngoune Feugap, Yabo Josiane Honkpehedji, Marguerite Massinga-Loembe, Hilaire Kenguele Moundounga, Anne Marie Nkoma Mouima, Lima Honorine Mbenkep, Linda Judith Wammes, Moustapha Mbow, Yvonne Kruize, Ghyslain Mombo-Ngoma, Aurore Larissa Bouyoukou Hounkpatin, Jean Claude Dejon Agobe, Issifou Saadou…
    Citation: SpringerPlus 2014 3:388
  19. Readily available inexpensive substrate with high product yield is the key to restoring acetone-butanol-ethanol (ABE) fermentation to economic competitiveness. Lactose-replete cheese whey tends to favor the pr...

    Authors: Victor Ujor, Ashok Kumar Bharathidasan, Katrina Cornish and Thaddeus Chukwuemeka Ezeji
    Citation: SpringerPlus 2014 3:387
  20. India’s third longest river, the Narmada, is studied here for the potential effects on native fish populations of river fragmentation due to various barriers including dams and a waterfall. The species we stud...

    Authors: Gulab D Khedkar, Rahul Jamdade, Amol Kalyankar, Anita Tiknaik, Tetsuzan Benny Ron and David Haymer
    Citation: SpringerPlus 2014 3:385
  21. Fanconi anemia (FA) is a genetically heterogeneous syndrome associated with increased cancer predisposition. The underlying genes govern the FA pathway which functions to protect the genome during the S-phase ...

    Authors: Anneke Haitjema, Berber M Mol, Irsan E Kooi, Maarten PG Massink, Jens AL Jørgensen, Davy AP Rockx, Martin A Rooimans, Johan P de Winter, Hanne Meijers-Heijboer, Hans Joenje and Josephine C Dorsman
    Citation: SpringerPlus 2014 3:381
  22. PTP1B is a prototypic enzyme of the superfamily protein tyrosine phosphatases (PTPs) which are critical regulators of tyrosine phosphorylation-dependent signaling events. It is a highly plausible candidate for...

    Authors: Xuan Thi-Anh Nguyen and Ly Le
    Citation: SpringerPlus 2014 3:380
  23. Studies were undertaken to identify pigeonpea, Cajanus cajan (L.) Millspaugh and the wild relative of pigeonpea, Cajanus scarabaeoides (L.) (accession ICPW 125,) genotypes that are hospitable to the pod borer, He...

    Authors: Shiddalingappa V Hugar, Hari C Sharma and Kondikallu Basavan Goud
    Citation: SpringerPlus 2014 3:378
  24. Fungi produce a broad spectrum of enzymes capable of degrading different substrates in nature. When the substrate is the tissue of a vertebrate host, these enzymes acts as a fungal virulence factor that increa...

    Authors: Henri Donnarumma Levy Bentubo and Olga Fischman Gompertz
    Citation: SpringerPlus 2014 3:377
  25. To obtain cellulases that are capable of degrading crystalline cellulose and cedar wood, metagenomic libraries were constructed from raw soil sample which was covered to pile of cedar wood sawdust or from its ...

    Authors: Toshio Mori, Ichiro Kamei, Hirofumi Hirai and Ryuichiro Kondo
    Citation: SpringerPlus 2014 3:365
  26. The success of Agrobacterium mediated plant transformation depends to a certain extent on appropriate selection of the A. tumefaciens strain for a particular plant species. Many stages in a plant transformation p...

    Authors: Farah Deeba, Muhammad Zeeshan Hyder, Shahzad Hussain Shah and Syed Muhammad Saqlan Naqvi
    Citation: SpringerPlus 2014 3:358
  27. Chitin-degrading bacterial strains were screened and tested for their ability to degrade shrimp-shell waste (SSW). Among the potential strains, B. cereus EW5 exhibited the highest chitin-degrading ability compare...

    Authors: Mohammed Shariful Azam, Eun Jung Kim, Han-Soeb Yang and Joong Kyun Kim
    Citation: SpringerPlus 2014 3:354
  28. Breast cancer is the most common cancer in women and autologous fat grafting is an important clinical application in treatment of post-surgical deformities. The simplicity of fat grafting procedures and the ab...

    Authors: Alessandra Bielli, Maria Giovanna Scioli, Pietro Gentile, Sara Agostinelli, Chiara Tarquini, Valerio Cervelli and Augusto Orlandi
    Citation: SpringerPlus 2014 3:345
  29. The concentrations of specific elements in the equine liver and kidneys are of practical relevance since horses are not only food-producing animals, but also partially serve as an indicator for the environment...

    Authors: Nadine Paßlack, Barbara Mainzer, Monika Lahrssen-Wiederholt, Helmut Schafft, Richard Palavinskas, Angele Breithaupt, Konrad Neumann and Jürgen Zentek
    Citation: SpringerPlus 2014 3:343
  30. We examined the effects of habitual exercise plus nutritional intervention through consumption of milk fat globule membrane (MFGM), a milk component, on aging-related deficits in muscle mass and function in se...

    Authors: Satoshi Haramizu, Takuya Mori, Michiko Yano, Noriyasu Ota, Kohjiro Hashizume, Atsuko Otsuka, Tadashi Hase and Akira Shimotoyodome
    Citation: SpringerPlus 2014 3:339
  31. Improved performance has been reported for master runners (i.e. athletes older than 40 years) in both single marathons and single ultra-marathons. This study investigated performance trends of age group ultra-mar...

    Authors: Christoph A Rüst, Thomas Rosemann, Matthias A Zingg and Beat Knechtle
    Citation: SpringerPlus 2014 3:331
  32. Basil (O. gratissimum L) is a aromatic and medicinal plant widely used in traditional medicine in Morocco. The aim of this work was to study the effect of three plant growth regulators gibberellic acid (GA), indo...

    Authors: Zakaria Hazzoumi, Youssef Moustakime and Khalid Amrani Joutei
    Citation: SpringerPlus 2014 3:321
  33. Therapeutic role of Nigella sativa (NS) seed oil fractions, methanolic extract (ME) and volatile oil (VO) and their constituents, thymoquinone (TQ) and limonene (LMN) in relation to lipidemic-oxidative stress in ...

    Authors: Shafeeque Ahmad and Zafarul H Beg
    Citation: SpringerPlus 2014 3:316
  34. This experiment was conducted with the aim to define the weaning age of camel calves managed with pastoral farmers in eastern Ethiopia. Twenty camel calves (11 males and 9 females) were randomly assigned into ...

    Authors: Merga B Chibsa, Yesihak Y Mummed, Mohamed Y Kurtu and Mengistu U Leta
    Citation: SpringerPlus 2014 3:313
  35. One of the main constraints hindering the increase of animal production in semi-arid regions of Africa is the inadequate supply of nutrients during the dry season. Incorporation of alternative feed resources i...

    Authors: Miguel A M Rodrigues, Ana L Lourenço, John W Cone, Fernando M Nunes, Ana S Santos, José M M Cordeiro, Cristina M V Guedes and Luis M M Ferreira
    Citation: SpringerPlus 2014 3:311
  36. Insect pests are among the most important constraints limiting sweetpotato (Ipomoea batatas) production in Africa. However, there is inadequate information about farmers’ knowledge, perceptions and practices in t...

    Authors: Joshua Sikhu Okonya, Robert OM Mwanga, Katja Syndikus and Jürgen Kroschel
    Citation: SpringerPlus 2014 3:303
  37. Chemotherapy is a common treatment for leukemia. Ruthenium complexes have shown potential utility in chemotherapy and photodynamic therapy. The identification of new chemotherapeutics agents is critical for fu...

    Authors: Flávia de Castro Pereira, Aliny Pereira de Lima, Cesar Augusto Sam Tiago Vilanova-Costa, Wanessa Carvalho Pires, Alessandra de Santana Braga Barbosa Ribeiro, Lucas Carlos Gomes Pereira, Luiz Alfredo Pavanin, Wagner Batista dos Santos and Elisângela de Paula Silveira-Lacerda
    Citation: SpringerPlus 2014 3:301