Virus | Culture | Multiplex | Reference | Sens. (%) | Spec. (%) |
|---|
+ | − | + | − | + | − | (95% CI) | (95% CI) |
|---|
Flu A | 125a
| 398 | 144 | 379 | 144 | 379 | 100 (100–100) | 95.2 (93.1–97.3) |
H1N1(2009) | 28b
| 495 | 36 d
| 487 | 36e
| 487 | 100 (100–100) | 98.4 (97.3–99.5) |
H3N2 | 88c
| 435 | 101d
| 422 | 101e
| 422 | 100 (100–100) | 97.0 (95.4–98.6) |
H7N9 | 9 | 514 | 9 | 514 | 9 | 514 | 100 (100–100) | 100 (100–100) |
RP | – | 523 | 523 | – | 523 | – | 100 (100–100) | 100 (100–100) |
- Values refer individually to the virus culture
-
Sens. sensitivity, Spec. specificity, 95% CI 95% confidence interval [CI]
-
aNineteen negative samples by cell culture consisted of eight pandemic H1N1 (2009) b and eleven H3N2 virus c by PCR and genomic sequence analysis. Indeterminate results were excluded from sensitivity and specificity calculations
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dTwo patients with H1N1(2009) virus-H3N2 virus coinfections, one was identified in throat swab specimen from patient with kidney transplantation history, the other was detected in sputum specimen from patient with multiple myeloma history. However, there was only H3N2 virus cultured in the two patients specimens, respectively
