Table 3 The characteristics of the included studies for IL-10 −1082 A/G polymorphism and urologic cancer risk
References | Country | Ethnicity | Case | Control | P value HWE | NOS score | ||||
|---|---|---|---|---|---|---|---|---|---|---|
n | Genotypes AA/AG/GG | Alleles A/G (%) | n | Genotypes AA/AG/GG | Alleles A/G (%) | |||||
Prostate cancer | ||||||||||
Dluzniewski et al. (2012) | USA | Mixed | 458 | 146/212/100 | 55.0/45.0 | 458 | 112/242/104 | 50.9/49.1 | 0.222 | 7 |
Faupel-Badger et al. (2008) | USA | Caucasian | 509 | 173/251/85 | 58.6/41.4 | 382 | 115/194/73 | 55.5/44.5 | 0.582 | 7 |
Ianni et al. (2013) | Italy | Caucasian | 171 | 79/74/18 | 45.2/54.8 | 96 | 25/43/28 | 48.4/51.6 | 0.312 | 7 |
Kesarwani et al. (2009) | India | Asian | 159 | 69/78/12 | 67.9/32.1 | 259 | 111/103/45 | 62.7/37.3 | 0.016 | 8 |
Liu et al. (2010) | China | Asian | 262 | 222/36/4 | 91.6/8.4 | 270 | 240/27/3 | 93.9/6.1 | 0.035 | 8 |
McCarron et al. (2002) | UK | Caucasian | 247 | 78/113/56 | 54.5/45.5 | 223 | 46/120/57 | 47.5/52.5 | 0.239 | 7 |
Michaud et al. (2006) | USA | Mixed | 1245 | 356/599/290 | 52.7/47.3 | 1763 | 523/857/383 | 54.0/46.0 | 0.364 | 8 |
Niu (2011) | China | Asian | 98 | 24/56/18 | 53.1/46.9 | 88 | 42/44/2 | 72.7/27.3 | 0.015 | 7 |
Omrani et al. (2009) | Iran | Caucasian | 41 | 5/31/5 | 50.0/50.0 | 103 | 16/77/10 | 52.9/47.1 | <0.0001 | 7 |
VanCleave et al. (2010) | USA | African | 192 | 22/95/75 | 36.3/63.7 | 660 | 92/280/288 | 35.2/64.8 | 0.074 | 8 |
Wang et al. (2009) | USA | Caucasian | 255 | 56/130/69 | 47.6/52.4 | 257 | 83/117/57 | 55.1/44.9 | 0.199 | 7 |
Winchester et al. (2015) | USA | Mixed | 832 | 206/434/192 | 63.0/37.0 | 836 | 204/429/203 | 50.1/49.9 | 0.447 | 8 |
Xu et al. (2005) | Sweden | Caucasian | 1383 | NA | 53.0/47.0 | 780 | NA | 51.0/49.0 | NA | 8 |
Zabaleta et al. (2008) | USA | Mixed | 541 | 131/277/133 | 49.8/50.2 | 523 | 144/280/99 | 54.3/45.7 | 0.072 | 8 |
Renal cancer | ||||||||||
Basturk et al. (2005) | Turkey | Caucasian | 29 | 17/9/3 | 74.1/25.9 | 50 | 32/13/5 | 77.0/23.0 | 0.060 | 7 |
Cozar et al. (2007) | Spain | Caucasian | 126 | 42/62/22 | 57.9/42.1 | 175 | 58/87/30 | 58.0/42.0 | 0.787 | 8 |
Havranek et al. (2005) | UK | Mixed | 147 | 65/56/26 | 63.3/36.7 | 149 | 45/69/35 | 53.4/46.6 | 0.395 | 7 |
Chang et al. (2016) | Taiwan | Asian | 92 | 71/16/5 | 85.9/14.1 | 580 | 444/107/29 | 85.8/14.2 | <0.0001 | 8 |
Bladder cancer | ||||||||||
Ahirwar et al. (2009) | India | Asian | 214 | 84/112/18 | 65.4/34.6 | 385 | 143/181/61 | 60.6/39.4 | 0.768 | 8 |
Chen et al. (2013) | China | Asian | 400 | 374/25/1 | 96.6/3.4 | 400 | 350/48/2 | 93.5/6.5 | 0.799 | 8 |