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Table 2 The characteristics of the included studies for IL-10 −819 C/T polymorphism and urologic cancer risk

From: Associations of IL-10 genetic polymorphisms with the risk of urologic cancer: a meta-analysis based on 18,415 subjects

References

Country

Ethnicity

Case

Control

P value HWE

NOS score

n

Genotypes CC/CT/TT

Alleles C/T (%)

n

Genotypes CC/CT/TT

Alleles C/T (%)

Prostate cancer

Dwivedi et al. (2015a, b)

India

Asian

291

68/131/92

45.9/54.1

291

60/151/80

46.6/53.4

0.466

8

Faupel-Badger et al. (2008)

USA

Caucasian

507

283/184/40

74.0/26.0

384

244/122/18

79.4/20.6

0.585

7

Kesarwani et al. (2009)

India

Asian

159

52/68/39

54.1/45.9

259

65/125/69

49.2/50.8

0.579

8

Liu et al. (2010)

China

Asian

262

34/108/120

33.6/66.4

270

28/110/132

30.7/69.3

0.477

8

Michaud et al. (2006)

USA

Mixed

1246

716/447/83

75.4/24.6

1762

964/659/139

73.4/26.6

0.078

8

VanCleave et al. (2010)

USA

African

191

76/85/30

62.0/38.0

635

246/278/111

60.6/39.4

0.037

8

Winchester et al. (2015)

USA

Mixed

611

372/206/33

77.7/22.3

659

408/217/34

78.4/21.6

0.464

8

Zabaleta et al. (2008)

USA

Mixed

526

308/180/38

75.7/24.3

494

249/204/41

71.1/28.9

0.931

8

Renal cancer

Basturk et al. (2005)

Turkey

Caucasian

29

13/14/2

69.0/31.0

50

24/19/7

67.0/33.0

0.320

7

Cozar et al. (2007)

Spain

Caucasian

127

81/37/9

78.3/21.7

175

98/63/14

74.0/26.0

0.394

8

Chang et al. (2016)

Taiwan

Asian

92

4/26/62

18.5/81.5

580

61/209/310

28.5/71.5

0.005

8

Bladder cancer

Ahirwar et al. (2009)

India

Asian

214

46/103/65

45.6/54.4

385

115/165/105

51.3/48.7

0.005

8

Chen et al. (2013)

China

Asian

400

42/140/218

28.0/72.0

400

64/168/168

37.0/63.0

0.047

8

  1. P value of HWE test <0.05, which reached the statistically significant level are indicated in italics
  2. HWE Hardy–Weinberg equilibrium, NOS Newcastle–Ottawa Quality Assessment Scale, NA not available