Table 2 Association between liver fibrosis and IL28B rs12979860 genotype in patients with HCV G1 infection, by region of enrolment
Patients, n (%) | IL28B rs12979860 genotype | |||
|---|---|---|---|---|
CC | TC | TT | p valuea | |
Asia (n = 25) | ||||
Cirrhosis/transition to cirrhosis | 8 (50.0) | 5 (55.6) | ND | |
No cirrhosis | 8 (50.0) | 4 (52.3) | ND | 0.7896 |
European (n = 1245) | ||||
Cirrhosis/transition to cirrhosis | 78 (20.2) | 168 (24.8) | 57 (31.7) | |
No cirrhosis | 309 (79.8) | 510 (75.2) | 123 (68.3) | 0.0030 |
Latin America (n = 137) | ||||
Cirrhosis/transition to cirrhosis | 9 (29.0) | 25 (33.8) | 10 (31.3) | |
No cirrhosis | 22 (71.0) | 49 (66.2) | 22 (68.8) | 0.8547 |
Middle East (n = 289) | ||||
Cirrhosis/transition to cirrhosis | 16 (24.6) | 57 (34.1) | 20 (35.1) | |
No cirrhosis | 49 (75.4) | 110 (65.9) | 37 (64.9) | 0.2022 |