Table 1 Association of serum miR-95-3p expression with clinicopathological features of osteosarcoma
From: Serum miR-95-3p is a diagnostic and prognostic marker for osteosarcoma
Clinicopathological features | No. of cases | Expression of miR-95-3p | P | |
|---|---|---|---|---|
Low | High | |||
Age (years) | ||||
≤15 | 59 | 40 | 19 | 0.234 |
>15 | 74 | 57 | 17 | |
Sex | ||||
Male | 71 | 53 | 18 | 0.634 |
Female | 62 | 44 | 18 | |
Location | ||||
Tibia | 58 | 44 | 14 | 0.375 |
Femur | 31 | 25 | 6 | |
Splinter bone | 22 | 16 | 6 | |
Humeral bone | 15 | 12 | 3 | |
Elsewhere | 7 | 5 | 2 | |
Tumor diameter (cm) | ||||
≤5 | 73 | 52 | 21 | 0.627 |
>5 | 60 | 45 | 15 | |
Serum level of lactate dehydrogenase | ||||
Elevated | 72 | 50 | 22 | 0.325 |
Normal | 61 | 47 | 14 | |
Serum level of alkaline phosphatase | ||||
Elevated | 87 | 64 | 23 | 0.822 |
Normal | 46 | 33 | 13 | |
Clinical stage | ||||
IIA | 49 | 27 | 22 | 0.000 |
IIB/III | 84 | 70 | 14 | |
Metastasis | ||||
Yes | 68 | 40 | 28 | 0.000 |
No | 65 | 57 | 8 | |
Response to chemotherapy | ||||
Good | 57 | 32 | 25 | 0.000 |
Poor | 76 | 65 | 11 | |