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Table 3 Amino acid sequence variants of the 115-amino-acid region of the E protein isolated from human plasma (A–G) and mosquito (a–h) samples compared with their corresponding master sequences (B and a)

From: Genomic studies of envelope gene sequences from mosquito and human samples from Bangkok, Thailand

Sequence variant No. of clones (% of total) Clones No. of amino acid substitutionsa Type of amino acid substitutionb
A 1 (1.8) 36-2 1 I339M
B 23 (42) 36-3, 4, 6, 8, 9, 10, 11, 12
45-1, 5, 6, 14, 25
47-1, 2, 3, 4, 5, 6, 7, 8, 9, 10
0
C 1 (1.8) 36-14 1 Q316R
D 19 (34.5) 37-1, 2, 3, 4, 5, 6, 8, 10, 16, 18
41-2, 4, 9, 18, 23, 24, 26, 27, 28
1 H346Y
E 1 (1.8) 45-15 1 D329G
F 9 (16.4) 50-2, 3, 4, 5, 6, 7, 8, 9, 10 2 G318R, R350S
G 1 (1.8) 50-1 3 D290G, G318R, R350S
Total 55   9  
a 13 56-4, 7, 15
275-24, 25, 27, 30, 32, 33, 35, 36, 37, 38
0
b 1 56-20 1 I335T
c 1 275-26 1 N276Y
d 1 275-31 2 N276T, P372L
e 1 275-39 1 K361E
f 1 275-40 1 M297I
g 9 56-2, 5, 6, 8, 10, 12, 13, 14, 17 1 H346Y
h 1 56-3 2 F279S, H346Y
Total 28   9  
  1. aNumber of substitutions relative to master sequences B and a
  2. bI, isoleucine; T, threonine; N, asparagine; Y, tyrosine; P, proline; L, leucine; K, lysine; E, glutamic acid; M, methionine; H, histidine; F, phenylalanine, S, serine; Q, glutamic acid; R, arginine; D, aspartic acid; G, glycine