Table 3 Amino acid sequence variants of the 115-amino-acid region of the E protein isolated from human plasma (A–G) and mosquito (a–h) samples compared with their corresponding master sequences (B and a)
From: Genomic studies of envelope gene sequences from mosquito and human samples from Bangkok, Thailand
Sequence variant | No. of clones (% of total) | Clones | No. of amino acid substitutionsa | Type of amino acid substitutionb |
|---|---|---|---|---|
A | 1 (1.8) | 36-2 | 1 | I339M |
B | 23 (42) | 36-3, 4, 6, 8, 9, 10, 11, 12 45-1, 5, 6, 14, 25 47-1, 2, 3, 4, 5, 6, 7, 8, 9, 10 | 0 | – |
C | 1 (1.8) | 36-14 | 1 | Q316R |
D | 19 (34.5) | 37-1, 2, 3, 4, 5, 6, 8, 10, 16, 18 41-2, 4, 9, 18, 23, 24, 26, 27, 28 | 1 | H346Y |
E | 1 (1.8) | 45-15 | 1 | D329G |
F | 9 (16.4) | 50-2, 3, 4, 5, 6, 7, 8, 9, 10 | 2 | G318R, R350S |
G | 1 (1.8) | 50-1 | 3 | D290G, G318R, R350S |
Total | 55 | Â | 9 | Â |
a | 13 | 56-4, 7, 15 275-24, 25, 27, 30, 32, 33, 35, 36, 37, 38 | 0 | – |
b | 1 | 56-20 | 1 | I335T |
c | 1 | 275-26 | 1 | N276Y |
d | 1 | 275-31 | 2 | N276T, P372L |
e | 1 | 275-39 | 1 | K361E |
f | 1 | 275-40 | 1 | M297I |
g | 9 | 56-2, 5, 6, 8, 10, 12, 13, 14, 17 | 1 | H346Y |
h | 1 | 56-3 | 2 | F279S, H346Y |
Total | 28 | Â | 9 | Â |