Skip to main content

Advertisement

Table 1 Nucleotide and amino acid sequence diversity of the E-gene region of DENV-2 from infected patients and mosquitoes

From: Genomic studies of envelope gene sequences from mosquito and human samples from Bangkok, Thailand

Sample Disease No. of clones   Amino acid sequences  
No. of substitutionsa Mean diversity (%)c Mean distance (10−2)c No. of substitutionsa Mean diversity (%)b Mean distance (10−2)c
Non-silent Silent
ID36 DF 10 2 0 2/3460 (0.058) 0.12 2 2/1150 (0.17) 0.35
ID37 DHF 10 10 110 120/3460 (3.47) 0.00 10 10/1150 (0.87) 0
ID41 DHF 9 9 81 90/3114 (2.89) 0.00 9 9/1035 (0.87) 0
ID45 DF 6 1 55 56/2076 (2.69) 0.19 1 1/690 (0.14) 0.29
ID47 DHF 10 0 2 2/3460 (0.058) 0.12 0 0/1150 (0.00) 0
ID50 DHF 10 21 91 112/3460 (3.24) 0.12 21 21/1150 (1.83) 0.17
Humans   55 42 340 382/19030 (2.01)   42 42/6325 (0.66)  
Mos56   14 12 112 124/4844 (2.56) 1.69 12 12/1610 (0.75) 0.63
Mos275   14 5 18 23/4844 (0.47) 0.89 5 5/1610 (0.31) 0.61
Mosquitoes   28 17 130 147/9660 (1.52)   17 17/3220 (0.53)  
  1. DF dengue fever, DHF dengue hemorrhagic fever
  2. aNumber of substitutions relative to master sequences hu2 and m1
  3. bNumber of nucleotide (or amino acid) substitutions divided by the total number of sequenced nucleotides (or amino acids) multiplied by 100
  4. cCalculated by pairwise comparison of nucleotide or amino acid sequences between clones within each sample using within- and between-group mean distances in MEGA