The assessment of myometrium perfusion in patients with uterine fibroid by arterial spin labeling MRI

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Table 3 Characteristics and ASL perfusion indexes of patients with fibroids treated with GnRH analogue

	Age	Diameter of fibroid (mm) Before ⇒ after GnRH treatment (reduction ratio)	Type of fibroid	Calibrated ASL perfusion index
	Age		Type of fibroid	(%) After ⇒ before
Case 1	39	86 ⇒ 80 (7%) 72 ⇒ 72 (0%) 56 ⇒ 42 (25%) 52 ⇒ 52 (0%)	Subserosal Subserosal Subserosal Intramural	15% (8.0 ⇒ 1.2)
Case 2	39	64 ⇒ 64 (0%) 40 ⇒ 25 (38%)	Intramural intramural	63% (9.9 ⇒ 6.3)
Case 3	44	18 ⇒ 16 (11%}	Submucosal	6.8% (12.9 ⇒ 0.88)
Case 4	45	96 ⇒ 70 (27%) 42 ⇒ 30 (29%)	Intramural Intramural	73% (11.7 ⇒ 8.6)
				Mean 39%

The subjects underwent their first MRI during the proliferative phase. After two or three rounds of GnRH analogue administration, the patients underwent a second MRI. ROIs were set at the same locations in myometrium beneath fibroids. ASL perfusion indexes before and after GnRH analogue treatments were calculated as (ASL value in uterus—ASL value in iliopsoas/gluteus muscle). Data were calibrated with ASL values in background