|
Test
|
Studies
|
Cut-off
|
n
|
TP
|
FP
|
FN
|
TN
|
AUC (95% CI)
|
Sensitivity (95% CI)
|
Specificity (95% CI)
|
|---|
|
PCT
|
59
|
0.96 (0.5, 1.7) ng/mla
|
7376
|
3173
|
847
|
1060
|
2296
|
0.85 [0.82, 0.88]
|
0.79 [0.75, 0.83]
|
0.78 [0.74, 0.81]
|
|
CRP
|
45
|
84 (38, 140) mg/l
|
5654
|
2356
|
719
|
1014
|
1565
|
0.77 [0.73, 0.81]
|
0.75 [0.69, 0.79]
|
0.67 [0.58, 0.74]
|
|
IL-6
|
22
|
138 (75, 220) pg/ml
|
3450
|
1376
|
403
|
625
|
1046
|
0.79 [0.75, 0.82]
|
0.72 [0.63, 0.80]
|
0.73 [0.67, 0.79]
|
|
sTREM-1
|
8
|
123 (635, 594) pg/ml
|
831
|
406
|
82
|
126
|
217
|
0.85 [0.82, 0.88]
|
0.78 [0.66, 0.87]
|
0.78 [0.65, 0.87]
|
|
Presepsin
|
9
|
600 (415, 647) pg/ml
|
1510
|
777
|
155
|
168
|
410
|
0.88 [0.85, 0.90]
|
0.84 [0.79, 0.88]
|
0.77 [0.68, 0.84]
|
|
LBP
|
5
|
30 (24.35, 32) μg/ml
|
1136
|
305
|
208
|
191
|
432
|
0.71 [0.67, 0.75]
|
0.62 [0.53, 0.71]
|
0.70 [0.59, 0.79]
|
|
CD64
|
4
|
–
|
558
|
300
|
13
|
76
|
169
|
0.96 [0.94, 0.97]
|
0.87 [0.75, 0.94]
|
0.93 [0.87, 0.96]
|
-
TP true positive, FP false positive, FN false negative, TN true negative
-
aMedian (25% percentiles, 75% percentiles)
