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Table 3 Functional outcome comparison

From: Comparisons of oncological and functional outcomes among radical retropubic prostatectomy, high dose rate brachytherapy, cryoablation and high-intensity focused ultrasound for localized prostate cancer

Variable

RRP (N = 97)

HDR (N = 161)

Cryo (N = 114)

HIFU (N = 120)

P value

Urethral stricture, N (%)

29 (29.9)

10 (6.2)

4 (3.3)

13 (10.8)

0.000

Secondary TURP or OIU, N (%)

28 (28.9)

18 (11.2)

10 (8.8)

16 (13.3)

0.000

Urinary incontinence, N (%)

11 (11.3)

1 (0.6)

2 (1.6)

3 (2.5)

0.000

Epididymitis, N (%)

2 (2.1)

6 (3.7)

8 (7.3)

7 (5.8)

0.311

Scrotal edema, N (%)

0 (0.0)

0 (0.0)

85 (74.7)

0 (0.0)

0.000

Rectal injury, N (%)

1 (1.0)

3 (1.9)

0 (0.0)

0 (0.0)

0.243

Irradiation cystitis, N (%)

0 (0.0)

6 (3.7)

0 (0.0)

0 (0.0)

0.006

Irradiation proctitis, N (%)

0 (0.0)

7 (4.3)

0 (0.0)

0 (0.0)

0.002

Erectile dysfunction at 12 months, N (%)a

32/38 (84.2)

30/34 (88.2)

44/50 (88.0)

21/32 (65.6)

0.042

IIEF-5 at 6 months (mean ± SD)a

6.08 ± 6.27

4.85 ± 5.52

4.02 ± 5.95

8.55 ± 8.41

0.031

IIEF-5 at 12 months (mean ± SD)a

6.33 ± 6.06

4.81 ± 5.47

3.61 ± 5.21

9.67 ± 7.74

0.003

IIEF-5 at 18 months (mean ± SD)a

6.74 ± 6.07

4.79 ± 5.32

4.50 ± 5.96

10.16 ± 8.11

0.008

IIEF-5 at 24 months (mean ± SD)a

5.48 ± 5.28

4.76 ± 5.48

4.18 ± 5.89

9.36 ± 6.33

0.067

IPSS at 6 months (mean ± SD)

9.55 ± 6.11

7.51 ± 5.81

10.43 ± 6.50

7.26 ± 4.41

0.009

IPSS at 12 months (mean ± SD)

9.69 ± 6.01

7.48 ± 5.56

9.54 ± 5.87

6.25 ± 3.42

0.021

IPSS at 18 months (mean ± SD)

9.52 ± 6.05

7.49 ± 5.67

9.15 ± 6.08

5.82 ± 3.75

0.047

IPSS at 24 months (mean ± SD)

9.31 ± 5.83

7.50 ± 5.43

9.04 ± 6.30

5.70 ± 3.53

0.184

QoL at 6 months (mean ± SD)

2.50 ± 1.59

2.27 ± 1.33

2.75 ± 1.41

1.90 ± 0.14

0.017

QoL at 12 months (mean ± SD)

2.52 ± 1.57

2.30 ± 1.42

2.59 ± 1.42

1.83 ± 1.01

0.097

QoL at 18 months (mean ± SD)

2.45 ± 1.56

2.32 ± 1.28

2.5 ± 1.41

1.86 ± 1.17

0.318

QoL at 24 months (mean ± SD)

2.50 ± 1.65

2.33 ± 1.47

2.47 ± 1.40

1.98 ± 1.4

0.794

  1. RRP radical retropubic prostatectomy, HDR high dose rate brachytherapy, Cryo cryoablation, HIFU high-intensity focused ultrasound, TURP transurethral resection of the prostate, OIU optic internal urethrotomy, SD standard deviation, IIEF-5 5-item version of the international index of erectile function, IPSS international prostate symptom score, QoL quality of life
  2. aErectile dysfunction and Mean scores for IIEF-5 were restricted to those men who reported IIEF-5 ≥ 17 at baseline