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Fig. 4 | SpringerPlus

Fig. 4

From: Alteration of NPY in hypothalamus and its correlation with leptin and ghrelin during the development of T2DM in a rat model

Fig. 4

RT-PCR analysis of hypothalamic GHS-R1a mRNA expression. The expression of GHS-R1a mRNA was detected respectively in normal control group (NC), DIO4 W group (feed on high fat diet for 4 weeks), DIO8 W group (fed a high-fat diet for 8 weeks), and T2DM groups (fed a high-fat diet for 8 weeks +STZ intraperitoneal injection), respectively. The OD values of the GHS-R1a mRNA expression in hypothalamus in the control, DIO4 W, DIO8 W, and T2DM groups were 1.38 ± 0.12, 1.29 ± 0.14, 0.94 ± 0.17 and 0.76 ± 0.16 respectively, which showing a downward trend (P < 0.01). *P < 0.05 vs. NC group

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