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Table 2 Shunt calculations and invasive hemodynamics before ASD closure

From: Efficacy and safety of transcatheter closure in adults with large or small atrial septal defects

  All patients (n = 49) Large device group (n = 19) Small device group (n = 30) p value
Shunt calculations
 Qp:Qs 1.57 (1.37, 2.32) 2.13 (1.49, 2.87) 1.50 (1.22, 2.00) 0.03
 Left–right shunt (%) 40 (31, 59) 59 (46, 67) 35 (27, 43) 0.0002
 Right–left shunt (%) 4 (0, 8) 6 (1, 10) 4 (0, 7) 0.20
Invasive hemodynamics (mmHg)
 RA mean pressure 6 (4, 9) 7 (5, 11) 5 (3, 8) 0.03
 RV end-diastolic pressure 8 (6, 10) 9 (8, 12) 6 (5, 8) 0.002
 PA systolic pressure 32 (27, 37) 35 (30, 45) 29 (25, 34) 0.004
 PA diastolic pressure 11 (8, 15) 11 (7, 16) 11 (8, 15) 0.56
 PA mean pressure 19 (15, 24) 24 (16, 28) 18 (14, 22) 0.03
 PCWP 11 (7, 15) 14 (11, 16) 9 (7, 13) 0.04
 Transpulmonary gradient 9 (5, 11) 10 (8, 11) 9 (4, 11) 0.27
  1. Shunt calculations were performed based on oximetric data using the Fick formula (Miller et al. 1974). Data are given as median (inter-quartile range)
  2. Qp:Qs pulmonary to systemic flow ratio, RA right atrium, RV right ventricle, PA pulmonary artery, PCWP pulmonary capillary wedge pressure