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Table 2 Shunt calculations and invasive hemodynamics before ASD closure

From: Efficacy and safety of transcatheter closure in adults with large or small atrial septal defects

 

All patients (n = 49)

Large device group (n = 19)

Small device group (n = 30)

p value

Shunt calculations

 Qp:Qs

1.57 (1.37, 2.32)

2.13 (1.49, 2.87)

1.50 (1.22, 2.00)

0.03

 Left–right shunt (%)

40 (31, 59)

59 (46, 67)

35 (27, 43)

0.0002

 Right–left shunt (%)

4 (0, 8)

6 (1, 10)

4 (0, 7)

0.20

Invasive hemodynamics (mmHg)

 RA mean pressure

6 (4, 9)

7 (5, 11)

5 (3, 8)

0.03

 RV end-diastolic pressure

8 (6, 10)

9 (8, 12)

6 (5, 8)

0.002

 PA systolic pressure

32 (27, 37)

35 (30, 45)

29 (25, 34)

0.004

 PA diastolic pressure

11 (8, 15)

11 (7, 16)

11 (8, 15)

0.56

 PA mean pressure

19 (15, 24)

24 (16, 28)

18 (14, 22)

0.03

 PCWP

11 (7, 15)

14 (11, 16)

9 (7, 13)

0.04

 Transpulmonary gradient

9 (5, 11)

10 (8, 11)

9 (4, 11)

0.27

  1. Shunt calculations were performed based on oximetric data using the Fick formula (Miller et al. 1974). Data are given as median (inter-quartile range)
  2. Qp:Qs pulmonary to systemic flow ratio, RA right atrium, RV right ventricle, PA pulmonary artery, PCWP pulmonary capillary wedge pressure