From: Efficacy and safety of transcatheter closure in adults with large or small atrial septal defects
All patients (n = 49) | Large device group (n = 19) | Small device group (n = 30) | p value | |
---|---|---|---|---|
Shunt calculations | ||||
Qp:Qs | 1.57 (1.37, 2.32) | 2.13 (1.49, 2.87) | 1.50 (1.22, 2.00) | 0.03 |
Left–right shunt (%) | 40 (31, 59) | 59 (46, 67) | 35 (27, 43) | 0.0002 |
Right–left shunt (%) | 4 (0, 8) | 6 (1, 10) | 4 (0, 7) | 0.20 |
Invasive hemodynamics (mmHg) | ||||
RA mean pressure | 6 (4, 9) | 7 (5, 11) | 5 (3, 8) | 0.03 |
RV end-diastolic pressure | 8 (6, 10) | 9 (8, 12) | 6 (5, 8) | 0.002 |
PA systolic pressure | 32 (27, 37) | 35 (30, 45) | 29 (25, 34) | 0.004 |
PA diastolic pressure | 11 (8, 15) | 11 (7, 16) | 11 (8, 15) | 0.56 |
PA mean pressure | 19 (15, 24) | 24 (16, 28) | 18 (14, 22) | 0.03 |
PCWP | 11 (7, 15) | 14 (11, 16) | 9 (7, 13) | 0.04 |
Transpulmonary gradient | 9 (5, 11) | 10 (8, 11) | 9 (4, 11) | 0.27 |