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Table 5 Contribution of baseline sociodemographic, clinical and quality of life variables for prediction of survival in lung cancer patients

From: Comparison of generic and lung cancer-specific quality of life instruments for predictive ability of survival in patients with advanced lung cancer

Variables entered

Model A

Model B

Model C

Model D

Model E

Model F

Male (ref: femalef)

1.95 (1.18–3.22)**

2.07 (1.25–3.43)**

2.16 (1.3–3.59)**

2.21 (1.33–3.67)**

1.87 (1.13–3.09)*

1.9 (1.13–3.18)*

Age ref: < 50

 50 ≤ Age < 60

0.76 (0.48–1.22)

0.82 (0.54–1.24)

0.86 (0.54–1.39)

0.89 (0.55–1.44)

0.80 (0.53–1.21)

0.75 (0.46–1.2)

 60 ≤ Age < 70

0.64 (0.45–0.92)*

0.91 (0.59–1.4)

0.66 (0.46–0.95)*

0.68 (0.47–0.99)*

0.94 (0.62–1.42)

0.64 (0.44–0.92)*

 ≥70

0.72 (0.5–1.03)

1.17 (0.72–1.89)

0.74 (0.52–1.07)

0.75 (0.52–1.09)

1.09 (0.68–1.76)

0.66 (0.46–0.96)*

 Stage 4 (ref: 3b)

2.05 (1.57–2.68)**

1.83 (1.39–2.42)**

1.85 (1.4–2.45)**

1.75 (1.32–2.33)**

2.13 (1.62-2.82)**

1.94 (1.47–2.55)**

 Comorbidity

1.35 (1.04–1.74)*

1.35 (1.04–1.75)*

1.39 (1.07–1.8)*

1.45 (1.11–1.89)**

1.28 (0.98–1.68)

1.38 (1.06–1.8)*

QLQ-C30

 PF(ref: ≥ 86.67)

 

1.00

 

1.00

  

 66.66 > PF ≤ 86.66

 

1.05 (0.74–1.49)

 

0.88 (0.6–1.29)

  

 PF ≤ 66.65

 

1.52 (1.03–2.24)*

 

1.24 (0.81–1.88)

  

 RF(ref: ≥ 100.0)

 

1.00

 

1.00

  

 66.66 > RF ≤ 99.99

 

1.14 (0.83–1.57)

 

1.03 (0.75–1.42)

  

 RF ≤ 66.65

 

1.26 (0.76–2.07)

 

1.36 (0.81–2.28)

  

 FA

  

1.34 (0.84–2.13)

1.34 (0.8–2.26)

  

 SL

  

1.23 (0.92–1.65)

1.22 (0.9–1.65)

  

 AP

  

1.1 (0.82–1.48)

1.08 (0.79–1.47)

  

 CO

  

1.49 (1.14–1.93)**

1.5 (1.15–1.98)**

  

EQ-5D

      

 Mobility

    

3.03 (1.65–5.56)**

 

 Selfcare

    

0.98 (0.39–2.43)

 

 Usual activities

    

1.76 (1.19–2.61)**

 

 Pain

    

0.97 (0.62–1.53)

 

 Mood

    

0.79 (0.42–1.5)

 

FACT-L

      

 Pwb (ref: ≥ 23.00)

     

1.00

 15 > Pwb ≤ 22

     

1.24 (0.81–1.91)

 Pwb ≤ 15

     

1.18 (0.83–1.67)

 Fwb (ref: ≥ 20.00)

     

1.00

 13 > Fwb ≤ 19

     

1.24 (0.84–1.84)

 Fwb ≤ 13

     

1.04 (0.74–1.48)

 LCS (ref: ≥ 21.00)

     

1.00

 15 > LCS ≤ 20

     

1.09 (0.76–1.57)

 LCS ≤ 15

     

0.7 (0.51–0.97)*

  1. * P < 0.05; ** P < 0.01
  2. PF Physical functioning, RF role functioning, FA fatigue, SL sleep problem, AP apetite loss, CO constipation, Pwb physical wellbeing, Fwb functional wellbeing, LCS Lung Cancer Scale