Table 4 Significance of FACT-L, EQ-5D and ECOG scores for overall survival of the lung cancer patients (Univariate and mulitvariate Cox’s regression results)
Variables FACT-L | Mean (SD) | N | Crude HR (95 % CI) | Adjusted HRa (95 % CI) |
|---|---|---|---|---|
Physical (ref = ≥ 23.00) | 18.9 | 90 | 1.00 | 1.00 |
15 > PWB ≤ 22 | (6.2) | 108 | 1.37 (1.02–1.84)* | 1.21 (0.89–1.63) |
≤15 | 101 | 1.83 (1.34–2.48)*** | 1.42 (1.03–1.94)* | |
Social/Family (ref = ≥ 27.00) | 23.5 | 67 | 1.00 | 1.00 |
20.0 > SWB ≤ 26.99 | (4.8) | 138 | 1.19 (0.90–1.57) | 1.07 (0.80–1.42) |
≤20 | 94 | 1.34 (0.73–2.46) | 1.37 (0.75–2.54) | |
Emotional (ref = ≥ 21.00) | 17.7 | 94 | 1.00 | 1.00 |
15 > EWB ≤ 20 | (5.3) | 94 | 1.17 (0.87–1.56) | 0.97 (0.71–1.33) |
≤15 | 110 | 1.07 (0.80–1.44) | 1.02 (0.75–1.37) | |
Functional (ref = ≥ 20.00) | 17.0 | 88 | 1.00 | 1.00 |
13 > FWB ≤ 19 | (6.3) | 90 | 1.07 (0.80–1.43) | 1.12 (0.83–1.51) |
≤13 | 121 | 1.51 (1.13–2.02)** | 1.51 (1.13–2.02)* | |
Lung Cancer Subscale (ref = ≥ 21.00) | 18.7 | 89 | 1.00 | 1.00 |
15 > LCS ≤ 20 | (5.3) | 93 | 0.88 (0.66–1.18) | 0.88 (0.66–1.18) |
≤15 | 117 | 1.52 (1.14–2.03)** | 1.42 (1.05–1.92)** | |
FACT-L (ref = ≥ 105.1) | 95.8 | 97 | 1.00 | 1.00 |
86.99 > FACT-L ≤ 105.1 | (20.1) | 99 | 1.20 (0.89–1.61) | 1.09 (0.80–1.47) |
≤86.99 | 102 | 1.63 (1.21–2.19)** | 1.31 (0.96–1.79) | |
FACT-L TOİb (ref = ≥ 23.00) | 54.7 | 94 | 1.00 | 1.00 |
15 > TOI ≤ 22 | (15.2) | 103 | 1.25 (0.93–1.67) | 1.18 (0.88–1.59) |
≤15 | 102 | 1.70 (1.26–2.29)** | 1.45 (1.07–1.98)* | |
FACT-G (ref: ≥ 85.00) | 77.1 | 99 | 1.00 | 1.00 |
46.99 > FACT-G ≤ 62 | (16.8) | 92 | 1.32 (0.98–1.74) | 1.23 (0.91–1.66) |
≤46.99 | 107 | 1.61 (1.20–2.16)** | 1.29 (0.95–1.76) | |
Equation5-D | ||||
Mobility (3 as reference) | 186 | 1.00 | 1.00 | |
1 + 2 | 113 | 4.29 (2.67–6.90)*** | 3.38 (2.05–5.26)*** | |
Self-care (3 as reference) | 242 | 1.00 | 1.00 | |
1 + 2 | 57 | 4.38 (2.14–8.98)*** | 3.30 (1.56–6.98)** | |
Usual activities (3 as reference) | 167 | 1.00 | 1.00 | |
1 + 2 | 132 | 1.68 (1.22–2.30)** | 1.96 (1.41–2.72)*** | |
Pain (3 as reference) | 127 | 1.00 | 1.00 | |
1 + 2 | 172 | 1.57 (1.07–2.98)* | 1.51 (1.03–2.23)* | |
Mood (3 as reference) | 194 | 1.00 | 1.00 | |
1 + 2 | 105 | 1.11 (0.61–2.04) | (0.54–1.86) | |
Equation5-D Index (1.0 as reference) 0.65 | 149 | 1.00 | 1.00 | |
Median value ≥ Index < 1.0 (0.36) | 61 | 1.26 (0.89–1.77) | 1.06 (0.75–1.51) | |
<Median value | 89 | 1.24 (0.94–1.65) | 1.27 (0.95–1.62) | |
Equation5-D VAS (≥79.00 as reference) 65.5 | 101 | 1.00 | 1.00 | |
50.01 > VAS ≤ 78.99 (20.5) | 95 | 1.24 (0.92–1.67) | 1.19 (0.83–1.51) | |
≤50.00 | 102 | 1.40 (1.04–1.87)* | 1.17 (0.86–1.60) | |
ECOG (Ecog 0 − 1 as reference) | 212 | 1.00 | 1.00 | |
ECOG (value 2 + 3 + 4) | 87 | 2.10(1.62–2.73)*** | 2.01(1.54–2.64)*** |