From: Design and synthesis of chalcone derivatives as potential non-purine xanthine oxidase inhibitors
Entry | CKOH (M) | Yield (%) |
---|---|---|
1a | 6 | 28.3 |
2a | 8 | 31.1 |
3a | 10 | 39.7 |
4a | 12 | 37.8 |
5a | 14 | 34.4 |
6b | 10 | 20.5 |
7b | 11 | 24.5 |
8b | 12 | 26.8 |
9b | 13 | 28.4 |
10b | 14 | 33.4 |
11b | −d | 32.8 |
12c | 10 | 8.3 |
13c | 11 | 17.5 |
14c | 12 | 22.8 |
15c | 13 | 7.1 |