Table 1 Demographic and clinical characteristics of patients with connective tissue disorders, chronic obstructive pulmonary disease, interstitial lung diseases, and the general population
Characteristic | General population (n = 640,177), n (%) | ILD (n = 859), n (%) | COPD (n = 15,686), n (%) | CTD (n = 7280), n (%) |
|---|---|---|---|---|
Sex | ||||
Male | 299,599 (46.80) | 570 (66.36) | 8832 (56.30) | 2105 (28.91) |
Female | 340,578 (53.20) | 289 (33.64) | 6854 (43.70) | 5175 (71.09) |
Age | ||||
Median (Q1, Q3) | 53 (46, 63) | 68 (59, 76) | 69 (60, 76) | 57 (49, 68) |
40–49 | 233,823 (36.52) | 67 (7.80) | 1195 (7.62) | 1825 (25.07) |
50–59 | 195,737 (30.58) | 161 (18.74) | 2525 (16.10) | 2235 (30.70) |
60–69 | 116,203 (18.15) | 242 (28.17) | 4251 (27.10) | 1716 (23.57) |
70–79 | 70,120 (10.95) | 276 (32.13) | 5223 (33.30) | 1193 (16.39) |
≥80 | 24,294 (3.79) | 113 (13.15) | 2492 (15.89) | 311 (4.27) |
Respiratory disease (prevalence) | ||||
Influenza and Pneumonia (J09–J14) | 3665 (0.57) | 18 (2.10) | 221 (1.41) | 87 (1.20) |
Bacterial Pneumonia (J15, J16) | 6187 (0.97) | 107 (12.46) | 1183 (7.54) | 115 (1.58) |
Active tuberculosis (A15) | 1121 (0.18) | 25 (2.91) | 335 (2.14) | 30 (0.41) |
Co-morbidity (prevalence) | ||||
Malignancy (C00–C97) | 32,140 (5.02) | 180 (20.95) | 2623 (16.72) | 529 (7.27) |
Diabetes (E10–E14) | 108,639 (16.97) | 309 (35.97) | 5385 (34.33) | 1894 (26.02) |
Chronic renal failure (N17–N19) | 7662 (1.20) | 50 (5.82) | 723 (4.61) | 191 (2.62) |
Previous myocardial infarction (I21, I22, I23, 25.2) | 5983 (0.93) | 35 (4.07) | 578 (3.68) | 114 (1.57) |
Congestive heart failure (I50) | 9584 (1.50) | 92 (10.71) | 1551 (9.89) | 186 (2.55) |
Varicose veins of lower extremities (I83, O22.0, O87.8) | 3655 (0.57) | 5 (0.58) | 105 (0.67) | 68 (0.93) |
Hospital admission | 98,780 (15.43) | 482 (56.11) | 7100 (45.26) | 1925 (26.44) |
Surgery | 207,567 (32.42) | 401 (46.68) | 7141 (45.52) | 2667 (36.63) |
Atrial fibrillation (I48) | 6340 (0.99) | 46 (5.36) | 829 (5.28) | 108 (1.48) |
Inflammatory bowel disease (N50–N52) | 294 (0.05) | 1 (0.12) | 10 (0.06) | 5 (0.07) |