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Table 3 Indications of IV pantoprazole administration before and after guideline establishment

From: Audit of IV pantoprazole: pattern of administration and compliance with guideline in a teaching hospital

Indications

Before guideline

(n = 200), (%)

After guideline

(n = 200), (%)

P valueb

NPO patients with erosive esophagitis (EE) with GERDa

2 (1.0)

5 (2.5)

0.00

Prophylaxis of rebleeding in NPO patientsa

7 (3.5)

16 (8.0)

 

Stress ulcer prophylaxis (SUP)in NPO patientsa

17 (8.5)

47 (23.5)

 

PUDc

2 (1.0)

2 (1.0)

 

GIB prophylaxis in patients receiving anti coagulation therapy

38 (19.0)

15 (7.5)

 

Abdominal pain

50 (25.0)

32 (16.0)

 

Undetermined indicationd

86 (42.0)

83 (41.5)

 
  1. aIndications approved for iv pantoprazole administration by the guideline
  2. bCalculated with Chi square test that < 0.05 was considered as statistically significant difference
  3. c PUD peptic ulcer disease
  4. dBased on the contents of the patients’s files we could not find any justification for the administration of the drug
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