Fig. 4From: Regulatory mechanisms of microRNAs in lung cancer stem cellsmiR-34a is a direct transcriptional target of p53 and is a negative regulator of the tumourigenic properties of CD44hi lung CSCs. As is shown above, over expression of miR-34a could inhibit regeneration of LCSCs by repressing CD44 and the Notch and p53 pathwaysBack to article page