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Table 3 Risk factors for disease flare within one year

From: Sleep disturbances in Japanese patients with inflammatory bowel disease and their impact on disease flare

Factors

Univariate

Multivariatea

OR

95 % CI

p value

OR

95 % CI

p value

Age (per 1 year)

0.97

0.95–1.00

0.09

0.99

0.96–1.01

0.27

Male sex

0.70

0.30–1.81

0.51

   

Body mass index (per 1 kg/m2)

1.01

0.89–1.14

0.87

   

Alcohol drinker

1.19

0.49–2.92

0.70

   

Smoker

1.93

0.49–7.62

0.35

   

Caffeine intake

1.02

0.45–2.30

0.97

   

IBD type, CD

0.65

0.21–2.00

0.46

   

Disease duration (per 1 year)

1.05

0.99–1.11

0.11

1.04

0.99–1.10

0.09

Active disease

1.87

0.65–5.40

0.25

   

Prior IBD surgery

1.21

0.60–2.42

0.60

   

Current medication use

 Steroids

0.96

0.12–7.80

0.97

   

 5-aminosalicylates

1.82

0.56–5.86

0.31

   

 Immunomodulators

1.37

0.52–3.65

0.52

   

 Anti-TNF biologics

0.62

0.18–2.10

0.44

   

 Sleep medications

1.75

0.46–6.69

0.42

   

 Sleep disturbances

2.69

1.14–6.34

0.02

3.09

1.47–6.43

<0.01

  1. Data are expressed as mean ± SD, or frequency. IBD inflammatory bowel disease, UC ulcerative colitis, CD Crohn’s disease, TNF tumor necrosis factor, OR odds ratio, CI confidence intervals
  2. a Adjusted for age, disease duration, and sleep disturbances
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