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Table 2 Clinical characteristics of the patients with or without disease flare within one year from enrollment

From: Sleep disturbances in Japanese patients with inflammatory bowel disease and their impact on disease flare

 

Disease flare (−)

Disease flare (+)

p value

(N = 85)

(N = 51)

Age (years)

43.3 ± 17.2

41.8 ± 18.9

0.62

Male sex (%)

52.9

54.9

0.86

Body mass index (kg/m2)

21.5 ± 3.0

21.4 ± 3.3

0.85

Alcohol drinking (%)

25.9

31.7

0.43

Smoking (%)

9.4

13.7

0.57

Caffeine intake (%)

47.1

51.0

0.72

IBD type

 UC

62.4

68.6

0.58

 CD

37.6

31.4

 

Disease duration (years)

10.7 ± 7.5

12.5 ± 10.2

0.29

Active disease (%)

11.8

23.5

0.09

Prior IBD surgery (%)

48.2

52.9

0.72

Medication used

 Steroids (%)

3.5

3.9

1.00

 5-aminosalicylates (%)

75.3

84.3

0.28

 Immunomodulators (%)

23.5

19.6

0.67

 Anti-TNF biologics (%)

29.4

19.6

0.23

 Sleep medications (%)

8.2

19.6

0.06

 Sleep disturbances (%)

34.1

60.8

<0.01

  1. Data are expressed as mean ± SD, or frequency. IBD inflammatory bowel disease, UC ulcerative colitis, CD Crohn’s disease, TNF tumor necrosis factor