Table 2 Influence of curcumin on metabolizing enzymes, antioxidants and lipid peroxides in kidney of control and experimental rats
Biochemical parameters | Group 1 | Group 2 | Group 3 | Group 4 |
|---|---|---|---|---|
Hexokinase (mM of glucose phosphorylated/h/mg protein) | 4.67 ± 0.16 | 3.34 ± 0.18* | 4.76 ± 0.13 | 5.62 ± 0.26# |
Glucose 6-phosphatase (mM of inorganic phosphorous liberated/min/mg protein) | 28.38 ± 1.72 | 46.27 ± 2.06* | 26.58 ± 1.75 | 37.19 ± 2.53# |
Fructose 1,6-bis phosphatase (mM of inorganic phosphorous liberated/h/mg protein) | 11.26 ± 1.88 | 26.97 ± 2.21* | 20.69 ± 1.37 | 18.91 ± 5.58# |
Catalase (units/mg of protein) | 58.55 ± 0.76 | 17.53 ± 1.64* | 49.44 ± 0.91 | 70.42 ± 0.69# |
Super oxide dismutase (units/mg protein) | 1518.34 ± 8.72 | 678.73 ± 10.71* | 1345.78 ± 16.94 | 1134.16 ± 11.86# |
Glutathione peroxidase (units/mg protein) | 169.20 ± 1.0 | 17.53 ± 1.0* | 102.94 ± 1.95 | 124.07 ± 2.18# |
Vitamin C (µM/mg of tissue) | 1.80 ± 0.04 | 0.72 ± 0.06* | 1.8 ± 0.04 | 1.27 ± 0.03# |
Vitamin E (µM/mg of tissue) | 4.03 ± 0.12 | 1.35 ± 0.04* | 3.52 ± 0.05 | 2.63 ± 0.07# |
Glutathione reductase (mg/100 g of tissue) | 1.40 ± 0.01 | 0.40 ± 0.04* | 1.36 ± 0.05 | 0.80 ± 0.01# |
Thiobarbituric acid reactive substances (mM/100 g tissue) | 0.14 ± 0.02 | 0.34 ± 0.02* | 0.12 ± 0.01 | 0.08 ± 0.003# |
Hydroperoxides (mM/100 g of tissue) | 540.10 ± 10 | 1271.17 ± 354.15* | 517.81 ± 46.55 | 640.24 ± 73.76# |