Table 1 Genotype and allele frequencies of CDH1 promotor polymorphisms in patients with nephrolithasis and controls
Genotypes and alleles | Patients (n = 101) n (%) | Controls (n = 114) n (%) | P values* | OR (95 % CI)* | P values** |
|---|---|---|---|---|---|
HphI (rs16260, −160 C > A) | 0.124 | ||||
AA | 10 (9.9) | 22 (19.2) | 1 | ||
CA | 39 (38.6) | 35 (30.7) | 2.80 (1.08–7.28) | 0.033 | |
CC | 52 (51.4) | 57 (50.0) | 2.16 (0.87–5.33) | 0.094 | |
CA + CC | 91 (90) | 92 (80.7) | 2.17 (0.97–4.85) | 0.053 | |
Alleles | 0.227 | ||||
A | 59 (29.2) | 79 (34.6) | 1 | ||
C | 143 (70.7) | 149 (65.3) | 1.28 (0.85–1.93) | 0.2281 | |
BanII (rs5030625, −347 G > GA) | 0.523 | ||||
GA/GA | 8 (7.92) | 5 (4.38) | 1 | ||
G/GA | 25 (24.7) | 27 (23.6) | 0.53 (0.14–2.05) | 0.359 | |
G/G | 68 (67.3) | 82 (71.9) | 0.45 (0.13–1.60) | 0.220 | |
G/G + G/GA | 93 (92) | 109 (95.5) | 0.53 (0.17–0.69) | 0.278 | |
Alleles | 0.333 | ||||
GA | 41 (20.2) | 37 (16.2) | 1 | ||
G | 161 (79.7) | 191 (83.7) | 0.76 (0.46–1.24) | 0.275 |