Table 1 Clinical data of included studies
Study | OR (95 % CI) | Study design | Patients | Adjust | Cancer or neoplasm | Country |
|---|---|---|---|---|---|---|
Neugut et al. (1998) | 1.18 (0.73–1.90) | Hospital-based case–control study | 256 patients with colorectal cancer (18.8 % prior CAD), 322 controls (14 % prior CAD) | Age, gender | Cancer | US |
Chan et al. (2006) | 2.12 (1.5–3.0) | Hospital-based case–control study | 1382 (373 patients with colorectal neoplasms, 168 patients with CAD) | Age, gender | Neoplasm | Hong Kong |
Chan et al. (2007) | 2.51 (1.43–4.35) | Hospital-based prospective observational study | 621 (68 patients with advanced colonic lesions, 206 patients with CAD) | Age, gender | Advanced colonic lesiona | Hong Kong, China |
Yang et al. (2010) | 1.96 (1.15–3.35) | Cross-sectional study | 488 men (217 patients with adenoma, 79 patients with significant CAD) | Age, smoking, metabolic syndrome | Adenoma | Korea |