Cardiac and testicular toxicity effects of the latex and ethanolic leaf extract of Calotropis procera on male albino rats in comparison to abamectin

Ahmed, Osama M.; Fahim, Hanaa I.; Boules, Magdy W.; Ahmed, Heba Y.

doi:10.1186/s40064-016-3326-7

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Table 8 Effect of latex and ethanolic leaf extract and abamectin on testicular GSH content, LPO and GPx, GST and SOD activities in normal rats

From: Cardiac and testicular toxicity effects of the latex and ethanolic leaf extract of Calotropis procera on male albino rats in comparison to abamectin

Treatments	Parameter
	GSH (nmol/100 mg tissue)		LPO (nmol/100 mg tissue)		GPx (U/g tissue)		GST (U/g tissue)		SOD (U/g tissue)
	4 weeks	8 weeks	4 weeks	8 weeks	4 weeks	8 weeks	4 weeks	8 weeks	4 week	8 weeks
Vehicle (CMC 1 %) control	86.78 ± 9.11^a	69.60 ± 6.12^b	13.68 ± 1.72^e	14.46 ± 2.40^e	71.89 ± 3.25^a	73.20 ± 6.68^a	976.18 ± 23.75^a	1011.18 ± 27.05^a	10.24 ± 1.77^a	9.33 ± 0.97^ab
1/20 LD₅₀ latex	68.97 ± 3.94^b	33.41 ± 5.68^e	16.30 ± 0.56^de	23.33 ± 1.97^bc	50.85 ± 6.52^cd	44.53 ± 3.42^cde	683.16 ± 37.74^bcd	787.50 ± 52.34^b	6.45 ± 0.38^cde	5.12 ± 0.44^defg
1/10 LD₅₀ latex	54.24 ± 1.85^cd	28.32 ± 3.02^ef	29.76 ± 1.98^a	30.06 ± 3.02^a	48.50 ± 4.38^cde	46.99 ± 4.29^cde	637.50 ± 42.81^cde	769.38 ± 29.28^b	5.53 ± 0.54^def	4.40 ± 0.24^efg
1/20 LD₅₀ ethanolic extract	64.06 ± 2.18^bc	19.03 ± 0.55^fg	25.37 ± 2.67^abc	21.35 ± 1.73^cd	55.13 ± 3.69^bc	49.06 ± 1.37^cd	753.96 ± 33.91^bc	673.09 ± 76.22^bcd	7.93 ± 0.98^bc	6.36 ± 0.56^cde
1/10 LD₅₀ ethanolic extract	48.05 ± 1.77^d	14.87 ± 0.59^g	28.10 ± 2.42^ab	22.56 ± 1.65^bc	49.44 ± 2.15^cd	37.27 ± 3.28^e	489.58 ± 6.99^f	584.21 ± 47.88^def	7.13 ± 0.46^cd	3.07 ± 0.76^g
1/20 LD₅₀ ABM	53.45 ± 4.58^cd	31.06 ± 3.74^e	21.72 ± 1.61^cd	21.80 ± 1.50^cd	64.25 ± 3.05^ab	51.47 ± 2.67^cd	672.29 ± 21.79^bcd	596.88 ± 66.45^def	6.99 ± 0.80^cd	4.05 ± 0.37^fg
1/10 LD₅₀ ABM	48.87 ± 3.79^d	18.42 ± 0.96^fg	23.33 ± 0.87^bc	27.92 ± 1.99^ab	52.10 ± 3.18^cd	41.90 ± 3.22^de	569.17 ± 29.95^def	546.87 ± 51.57^ef	5.06 ± 0.48d^efg	3.59 ± 0.40^fg
F-probability	P < 0.001		P < 0.001		P < 0.001		P < 0.001		P < 0.001
LSD at 5 % level	11.946		5.6821		11.3121		124.2059		2.1784
LSD at 1 % level	16.0879		7.6522		15.2342		167.2704		2.9337

Data are expressed as mean ± SE
Number of animals in each group is six
For each parameter, means, which do not share the same superscript symbol(s), are significantly different at P < 0.05

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