Cardiac and testicular toxicity effects of the latex and ethanolic leaf extract of Calotropis procera on male albino rats in comparison to abamectin

Ahmed, Osama M.; Fahim, Hanaa I.; Boules, Magdy W.; Ahmed, Heba Y.

doi:10.1186/s40064-016-3326-7

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Table 7 Effect of latex and ethanolic leaf extract and abamectin on cardiac GSH content, LPO and GPx, GST and SOD activities in normal rats

From: Cardiac and testicular toxicity effects of the latex and ethanolic leaf extract of Calotropis procera on male albino rats in comparison to abamectin

Treatments	Parameter
	GSH (nmol/100 mg tissue)		LPO (nmol/100 mg tissue)		GPx (U/g tissue)		GST (U/g tissue)		SOD (U/g tissue)
	4 weeks	8 weeks	4 weeks	8 weeks	4 weeks	8 weeks	4 weeks	8 weeks	4 week	8 weeks
Vehicle (CMC 1 %) control	163.34 ± 1.44^a	143.42 ± 0.93^b	46.31 ± 0.71^f	47.85 ± 2.11^f	84.85 ± 0.99^a	85.50 ± 2.25^a	489.93 ± 14.33^ab	506.25 ± 3.74^a	14.35 ± 0.18^bc	15.31 ± 0.71^ab
1/20 LD₅₀ latex	109.87 ± 7.52^cd	119.65 ± 8.74^c	64.50 ± 3.68^de	61.84 ± 1.13^e	77.39 ± 2.04^bc	69.00 ± 1.24^defg	447.92 ± 2.69^ef	481.80 ± 2.60^bc	9.07 ± 0.23^e	11.95 ± 0.29^d
1/10 LD₅₀ latex	69.69 ± 6.29^e	97.71 ± 6.10^d	72.82 ± 2.17^cd	67.16 ± 2.65^cde	69.93 ± 2.70^defg	63.96 ± 0.43^g	429.86 ± 12.39^f	460.07 ± 6.63^cde	1.93 ± 0.23^h	4.62 ± 0.30^g
1/20 LD₅₀ ethanolic extract	68.39 ± 6.23^e	108.40 ± 1.00^cd	65.19 ± 3.75^de	59.78 ± 4.33^e	68.06 ± 1.69^efg	79.63 ± 1.3^ab	480.49 ± 13.70^bc	454.51 ± 8.65^de	15.71 ± 0.14^a	6.84 ± 0.78^f
1/10 LD₅₀ ethanolic extract	45.35 ± 5.28^f	102.50 ± 8.26^cd	84.53 ± 4.66^a	72.71 ± 2.56^cd	63.96 ± 2.96^g	77.11 ± 0.74^bc	472.31 ± 5.63^bcd	386.06 ± 8.17^h	2.11 ± 0.25^h	4.04 ± 0.06^g
1/20 LD₅₀ ABM	118.73 ± 11.35^c	116.51 ± 4.20^c	76.55 ± 6.46^abc	72.56 ± 2.02^cd	74.22 ± 2.59^bcd	72.35 ± 3.33^cdef	470.49 ± 3.39^bcde	487.85 ± 0.77^ab	13.39 ± 0.11^c	7.12 ± 0.15^f
1/10 LD₅₀ ABM	77.61 ± 0.70^e	77.43 ± 1.31^e	84.30 ± 5.44^ab	74.19 ± 3.12^bcd	72.54 ± 2.35^cde	84.85 ± 0.99^a	447.92 ± 7.12^ef	395.83 ± 3.36^g	12.26 ± 0.22^d	4.84 ± 0.38^g
F-probability	P < 0.001		P < 0.001		P < 0.001		P < 0.001		P < 0.001
LSD at 5 % level	17.2065		10.2926		6.0102		22.709		1.013
LSD at 1 % level	23.1723		13.8613		8.0941		30.5827		1.3642

Data are expressed as mean ± SE
Number of animals in each group is six
For each parameter, means, which do not share the same superscript symbol(s), are significantly different at P < 0.05

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