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Table 5 Effect of latex and ethanolic leaf extract and abamectin on TNF-α and IL-4 levels in serum of normal rats

From: Cardiac and testicular toxicity effects of the latex and ethanolic leaf extract of Calotropis procera on male albino rats in comparison to abamectin

Treatment

Parameter

TNF-α (pg/ml)

IL-4 (ng/ml)

4 weeks

8 weeks

4 weeks

8 weeks

Vehicle (CMC 1 %) control

36.72 ± 1.02h

38.72 ± 0.62h

202 ± 4.37a

197 ± 1.64a

1/20 LD50 latex

78.55 ± 6.28fg

72.55 ± 7.10g

130.7 ± 13.63c

170.5 ± 15.17b

1/10 LD50 latex

91.43 ± 6.12def

80.30 ± 5.74efg

101.53 ± 3.99d

112.9 ± 5.34cd

1/20 LD50 ethanolic extract

102.42 ± 6.53cd

92.40 ± 3.67de

179.3 ± 7.96ab

186.97 ± 4.27ab

1/10 LD50 ethanolic extract

109.85 ± 4.29bc

100.98 ± 3.52cd

138 ± 11.67c

181.4 ± 3.96ab

1/20 LD50 abamectin

100.67 ± 5.61cd

86.62 ± 3.83ef

184.9 ± 8.89ab

199.27 ± 2.80a

1/10 LD50 abamectin

124 ± 3.08a

117.95 ± 1.08ab

134.97 ± 19.22c

197.23 ± 1.95a

F-probability

P < 0.001

 

P < 0.001

 

LSD at 5 % level

13.4927

 

26.4573

 

LSD at 1 % level

18.1709

 

35.6306

 
  1. Data are expressed as mean ± SE
  2. Number of animals in each group is six
  3. For each parameter, means, which do not share the same superscript symbol(s), are significantly different at P < 0.05