Cardiac and testicular toxicity effects of the latex and ethanolic leaf extract of Calotropis procera on male albino rats in comparison to abamectin

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Table 1 Effect of latex and ethanolic leaf extract and abamectin on serum CK-MB, AST and LDH activities of normal rats

Treatments	Parameter
	CK-MB (U/L)		AST (U/L)		LDH (U/L)
	4 weeks	8 weeks	4 weeks	8 weeks	4 weeks	8 weeks
Vehicle (CMC 1 %) control	93.26 ± 5.49^f	94.99 ± 4.70^f	96.57 ± 2.55^fg	86.65 ± 6.01^g	749.58 ± 80.83^g	738.89 ± 80.25^g
1/20 LD₅₀ latex	178.16 ± 21.79^bcde	103.37 ± 18.49^f	124.68 ± 5.48^abcd	116.64 ± 2.27^bcde	2897.51 ± 310.79^bc	2775.36 ± 146.39^c
1/10 LD₅₀ latex	217.63 ± 25.89^b	185.50 ± 18.35^bcde	138.67 ± 5.95^a	126.66 ± 10.24^ab	3488.61 ± 182.80^a	3471.67 ± 25.63^a
1/20 LD₅₀ ethanolic extract	177.62 ± 16.82^bcde	135.00 ± 3.09^ef	109.43 ± 1.59^cdef	105.98 ± 3.26^ef	3341.78 ± 296.19^ab	1533.90 ± 23.68^f
1/10 LD₅₀ ethanolic extract	366.10 ± 31.39^a	140.34 ± 3.69^def	140.50 ± 6.32^a	125.98 ± 6.36^ab	3457.25 ± 325.48^a	2085.50 ± 223.34^de
1/20 LD₅₀ ABM	194.03 ± 20.98^bcd	142.40 ± 16.58^cdef	108.87 ± 1.32^def	99.45 ± 8.72^fg	2195.30 ± 141.03^d	1283 ± 10.57^fg
1/10 LD₅₀ ABM	195.09 ± 21.01^bc	201.76 ± 23.23^b	111.10 ± 4.70^bcdef	125.34 ± 3.99^abc	3194.32 ± 256.22^abc	1581 ± 81.17^ef
F-probability	P < 0.001		P < 0.001		P < 0.001
LSD at 5 % level	53.828		16.0947		549.503
LSD at 1 % level	72.491		21.675		735.985

Data are expressed as mean ± SE
Number of animals in each group is six
For each parameter, means, which do not share the same superscript symbol(s), are significantly different at P < 0.05