Skip to main content

Table 2 Efflux ratio for digoxin in presence and absence of elacridar in the Caco-2 cell lines

From: Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs

Treatment AP-BL transport BL-AP transport Efflux ratio (BL-AP/AP-BL)
Digoxin10 µM 5.18E−08 1.80E−06 34.77 ± 6.7
Digoxin + Elacridar 5 µM 1.52E−07 2.79E−07 1.83 ± 0.08