Table 2 Efflux ratio for digoxin in presence and absence of elacridar in the Caco-2 cell lines
Treatment | AP-BL transport | BL-AP transport | Efflux ratio (BL-AP/AP-BL) |
|---|---|---|---|
Digoxin10 µM | 5.18E−08 | 1.80E−06 | 34.77 ± 6.7 |
Digoxin + Elacridar 5 µM | 1.52E−07 | 2.79E−07 | 1.83 ± 0.08 |