Fig. 2

In vivo P-gp inhibition study: a Mean plasma concentration, b Mean brain concentration, c Plasma AUC. d Brain AUC and e Brain to plasma ratio of Quinidine when combined with Quercetin and Silymarin. Each data point was represented as mean ± SEM (n = 3–4). *p < 0.05; **p < .0.01 and ***p < 0.001 versus Quinidine alone groups