Fig. 1

In vitro Caco-2 based P-gp inhibition study: a Efflux ratio of Digoxin and Digoxin with Elacridar, b Efflux ratio of Digoxin 10 µM alone, Digoxin in presence of Quercetin and Silymarin (50 and 100 µM). Each data point was represented as mean ± SEM (n = 3–4). *p < 0.05; **p < 0.01 and ***p < 0.001 vs Quinidine alone groups. (D digoxin, E elacridar, Qr quercetin, S silymarin)