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Table 2 Histological assessment of myocyte size, vessel density and myocardial fibrosis

From: The effect of long-term amiodarone administration on myocardial fibrosis and evolution of left ventricular remodeling in a porcine model of ischemic cardiomyopathy

Histological parameters

Group

Mean ± SD

p value

Myocyte size (baseline) (μm2)

Amiodarone

326.24 ± 58.30

0.197

Control

264.60 ± 71.70

Vascular density (baseline) (vessels/0.1 mm2)

Amiodarone

150 ± 100

0.073

Control

340 ± 90

Myocardial fibrosis (baseline) (%/area)

Amiodarone

8.44 ± 7.21

0.839

Control

9.48 ± 5.57

Myocyte size (3 months) (μm2)

Amiodarone

638.22 ± 259.70

0.874

Control

607.31 ± 245.06

Vascular density (3 months) (vessels/0.1 mm2)

Amiodarone

150 ± 100

0.150

Control

310 ± 100

Myocardial fibrosis (3 months) (%/area)

Amiodarone

11.60 ± 2.98

0.474

Control

16.43 ± 14.12