Table 2 Characteristics of children with or without bronchiolitis obliterans after respiratory adenoviral infection
Characteristics | Non-BO (n = 530) | BO (n = 14) | p |
|---|---|---|---|
Gender | 0.127 | ||
Male | 385 (72.6 %) | 13 (92.9 %) | |
Female | 145 (27.4 %) | 1 (7.1 %) | |
Age (months) | 23.5 (1–144) | 15.5 (6–72) | 0.339 |
History of breast-feeding | 305 (57.5 %) | 9 (64.3 %) | 0.818 |
Premature birth | 34(6.4 %) | 1 (7.1 %) | 0.610 |
Number of siblings | 0 (0–3) | 1 (0–2) | 0.096 |
Diagnosis | 0.014 | ||
No pneumonia | 150 (28.3 %) | 0 (0.0 %) | |
Pneumonia | 380 (71.7 %) | 14 (100.0 %) | |
Hypoxemia | 110 (20.8 %) | 11 (78.6 %) | 0.000 |
CRP | 14.92 (0.00–264.74) | 26.25 (0.51–116.20) | 0.155 |
Blood neutrophil count (×109/l) | 5.49 (0.54–32.8) | 4.46 (2.19–14.44) | 0.767 |
Blood lymphocyte count (×109/l) | 3.24 (0.36–35.29) | 2.23 (0.83–6.77) | 0.025 |
ALT (IU/ml) | 18 (3–372) | 16 (7–112) | 0.405 |
AST (IU/ml) | 41 (15–1400) | 40.5 (29–391) | 0.495 |
CK (IU/ml) | 88.5 (11–5413) | 91 (17–1038) | 0.941 |
CK–MB (IU/ml) | 25 (1–436) | 24 (13–169) | 0.959 |
LDH (IU/ml) | 348 (14–10983) | 523.5 (254–1945) | 0.033 |
Mycoplasma co-infection | 143 (27.0 %) | 4 (28.6) | 0.999 |
Bacterial co-infection | 46 (8.7 %) | 0 (0.0 %) | 0.621 |
Sepsis | 9 (1.7 %) | 0 (0.0 %) | 0.999 |
Use of γ-globulin intravenously | 195 (36.8 %) | 12 (85.7 %) | 0.000 |
Use of antibiotics | 509 (96.0 %) | 14 (100.0 %) | 0.999 |
Use of glucocorticoids | 129 (24.3 %) | 11 (78.6 %) | 0.000 |
Mechanical ventilation | 29 (5.5 %) | 5 (35.7 %) | 0.001 |
Length of fever (days) | 7 (0–62) | 15.5 (6–30) | 0.000 |
Length of hospital stay (days) | 7 (2–74) | 19.5 (8–55) | 0.000 |