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Table 2 Acetylcholinesterase inhibitory activity of extract, fractions (F1–F4) and five compounds isolated from the leaves and twigs of Artemisia annua

From: Anti-inflammatory and acetylcholinesterase activity of extract, fractions and five compounds isolated from the leaves and twigs of Artemisia annua growing in Cameroon

Samples

% Inhibition

IC50 (µg/mL)

Crude extract

71.83 ± 7.32a

87.43 ± 4.04a

Fractions

  

 F1

58.33 ± 6.00b

379.82 ± 20.16b

 F2

88.67 ± 5.28c

36.75 ± 3.59c

 F3

69.00 ± 9.26b

104.08 ± 8.60d

 F4

91.17 ± 7.59c,d

28.82 ± 5.15e

Compounds

  

 1

71.67 ± 7.90a,b

29.34 ± 4.92e

 2

56.34 ± 4.92b

70 ± 5.97f

 3

80.00 ± 9.67b,c

27.14 ± 5.16e

 4

58.22 ± 2.73b

67.07 ± 7.32 g

 5

68.00 ± 5.51b

37.73 ± 2.45c,h

Galantamine

88.22 ± 2.73c

8.22 ± 2.73i

  1. Data represent the mean ± SD of three independent experiments; values with different letters are significantly different at p < 0.05, according to the Fisher’s least significant difference (LSD) analysis