Table 3 Association of SNPs with CAD in different genetic models
SNPs | Model | Genotype | Control (%) | Case (%) | χ 2 | P | OR (95 % CI)* |
|---|---|---|---|---|---|---|---|
rs11536889 | Co-dominant | G/G | 323 (62.6) | 346 (60.8) | 0.570 | 0.752 | 1.00 |
| Â | Â | G/C | 174 (33.7) | 198 (34.8) | 1.055 (0.714, 1.558) | ||
| Â | Â | C/C | 19 (3.7) | 25 (4.4) | 1.293 (0.503, 3.326) | ||
| Â | Dominant | G/G | 323 (62.6) | 346 (60.8) | 0.366 | 0.545 | 1.00 |
| Â | Â | G/C+C/C | 193 (37.4) | 223 (39.2) | 1.100 (0.755, 1.603) | ||
| Â | Recessive | G/G+G/C | 497 (96.3) | 544 (95.6) | 0.352 | 0.553 | 1.00 |
| Â | Â | C/C | 19 (3.7) | 25 (4.4) | 1.270 (0.498, 3.235) | ||
rs1927907 | Co-dominant | G/G | 276 (53.8) | 320 (56.3) | 0.702 | 0.704 | 1.00 |
| Â | Â | A/G | 200 (39.0) | 209 (36.8) | 1.126 (0.764, 1.659) | ||
| Â | Â | A/A | 37 (7.2) | 39 (6.9) | 1.139 (0.534, 2.429) | ||
| Â | Dominant | G/G | 276 (53.8) | 320 (56.3) | 0.701 | 0.402 | 1.00 |
| Â | Â | A/G+A/A | 237 (46.2) | 248 (43.7) | 1.134 (0.783, 1.643) | ||
| Â | Recessive | G/G+A/G | 476 (92.8) | 529 (93.1) | 0.049 | 0.824 | 1.00 |
| Â | Â | A/A | 37 (7.2) | 39 (6.9) | 1.085 (0.517, 2.275) | ||
rs1927911 | Co-dominant | T/T | 86 (16.8) | 88 (15.4) | 0.409 | 0.815 | 1.00 |
| Â | Â | C/T | 253 (49.5) | 289 (50.4) | 0.844 (0.494, 1.442) | ||
| Â | Â | C/C | 174 (33.7) | 196 (34.2) | 0.797 (0.455, 1.398) | ||
| Â | Dominant | T/T | 86 (16.8) | 88 (15.4) | 0.398 | 0.528 | 1.00 |
| Â | Â | C/T+C/C | 427 (83.2) | 485 (84.6) | 0.824 (0.496, 1.370) | ||
| Â | Recessive | T/T+C/T | 340 (66.3) | 377 (65.8) | 0.028 | 0.867 | 1.00 |
| Â | Â | C/C | 173 (33.7) | 196 (34.2) | 0.926 (0.630, 1.361) |