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Table 2 Structural connectivity values for the three groups

From: Structural connectivity profile of scans without evidence of dopaminergic deficit (SWEDD) patients compared to normal controls and Parkinson’s disease patients

Connections

Structural connectivity (mean ± SD)

Corrected p value

NC

SWEDD

PD

PD-NC

SWEDD-NC

SWEDD-PD

Associative cortex–caudate

0.671 ± 1.381

0.299 ± 0.453

0.232 ± 0.319

0.017

0.054

0.214

Associative cortex–putamen

3.452 ± 1.561

3.471 ± 1.517

3.734 ± 1.771

0.228

0.487

0.232

Associative cortex–thalamus

0.833 ± 0.488

0.650 ± 0.367

1.173 ± 0.750

0.009

0.032

<0.001

Limbic cortex–caudate

2.197 ± 1.463

1.902 ± 1.310

0.710 ± 1.215

<0.001

0.162

<0.001

Limbic cortex–putamen

3.175 ± 1.272

3.271 ± 1.474

2.557 ± 1.147

0.013

0.387

0.008

Limbic cortex–thalamus

1.535 ± 0.810

1.379 ± 0.866

1.054 ± 0.889

0.005

0.194

0.048

Sensorimotor cortex–caudate

0.430 ± 0.993

0.170 ± 0.471

0.053 ± 0.076

<0.001

0.062

0.016

Sensorimotor cortex–putamen

1.250 ± 0.742

1.485 ± 0.930

1.728 ± 1.108

0.011

0.010

0.027

Sensorimotor cortex–thalamus

0.964 ± 0.574

0.947 ± 0.537

1.019 ± 0.703

0.325

0.511

0.292

Pallidum–caudate

0.676 ± 0.644

0.838 ± 0.744

0.631 ± 0.825

0.374

0.145

0.112

Pallidum–putamen

2.166 ± 0.898

1.840 ± 0.917

1.283 ± 0.522

<0.001

0.045

<0.001

Pallidum–thalamus

0.799 ± 0.519

0.926 ± 0.523

0.565 ± 0.452

0.007

0.143

<0.001

Putamen–thalamus

0.439 ± 0.437

0.477 ± 0.388

0.346 ± 0.298

0.132

0.295

0.044

Substantia nigra–putamen

0.004 ± 0.017

0.001 ± 0.004

0.004 ± 0.015

0.496

0.179

0.192

Substantia nigra–thalamus

0.001 ± 0.005

0.004 ± 0.012

0.009 ± 0.003

0.193

0.045

0.223

Substantia nigra–pallidum

0.096 ± 0.243

0.095 ± 0.363

0.160 ± 0.129

0.210

0.485

0.350

  1. Structural connectivity values based on fiber density were reported for 16 connections within the CBGT circuit. The values were reported as the mean ± standard deviation (SD). Group-wise differences in NC-PD, SWEDD-NC and SWEDD-PD comparisons were reported using corrected p values. The italicised text shows identified connections with significant differences among the three comparisons