Carbapenem resistant Pseudomonas aeruginosa and Acinetobacter baumannii at Mulago Hospital in Kampala, Uganda (2007–2009)

Kateete, David P.; Nakanjako, Ritah; Namugenyi, Juliet; Erume, Joseph; Joloba, Moses L.; Najjuka, Christine F.

doi:10.1186/s40064-016-2986-7

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Table 2 Characteristics of carbapenem-resistant Pseudomonas aeruginosa isolates from hospitalized patients and environment at Mulago Hospital in Kampala, 2007–2009

From: Carbapenem resistant Pseudomonas aeruginosa and Acinetobacter baumannii at Mulago Hospital in Kampala, Uganda (2007–2009)

Isolate no.	Month/year of isolation	Source	Isolation material	Resistance pattern	MHT	IMP-EDTA	Carbapenemase genes				Other genetic determinants
Isolate no.	Month/year of isolation	Source	Isolation material	Resistance pattern	MHT	IMP-EDTA	bla _IMP-like^a	bla _VIM-like^a	bla _SPM-like	bla _NDM-like	Class 1 Integrons
J085	02/2008	Patient	Pus	CIP-CN-CAZ-ATM-AK-MEM	Yes	No	No	Yes	No	No	No
J105	03/2008	Patient	Pus	CN-CAZ-MEM	No	Yes	Yes	No	No	No	No
1665	07/2008	Patient	Ear swab	TZP-ATM-FEP-IMP	No	Yes	Yes	No	No	No	Yes
2545	06/2009	Patient	Sputum	CIP-CN-CAZ-ATM-AK-FEP-IMP	Yes	No	No	Yes	No	No	No
2608	06/2009	Patient	Tracheal aspirate	CIP-CN-CAZ-ATM-FEP-IMP-MEM	No	Yes	No	Yes	No	No	Yes
2665	08/2009	Patient	Sputum	CIP-ATM-AK-FEP-IMP-MEM	Yes	No	Yes	No	No	No	Yes
7545	09/2009	Patient	Pus	CIP-CN-TZP-CAZ-ATM-FEP-IMP-MEM	No	Yes	No	Yes	No	No	No
9608	09/2009	Patient	Sputum	CIP-CN-TZP-CAZ-ATM-FEP-IMP	Yes	Yes	Yes	No	No	No	Yes
PA0504	09/2009	Patient	Tracheal aspirate	CN-CAZ-AK-FEP-IMP-MEM	No	No	No	No	No	No	No
PA1688	09/2009	Patient	Tracheal aspirate	CIP-CN-TZP-CAZ-AK-FEP-IMP	No	Yes	No	Yes	No	No	No
J041-2	11/2009	Environment	Wet floor	CIP-CN-TZP-CAZ-ATM-AK-FEP-MEM	No	Yes	No	No	Yes	No	Yes
J049-1	11/2009	Environment	Wet floor	CIP-CN-TZP-CAZ-ATM-FEP-IMP-MEM	No	Yes	Yes	No	No	No	No
J052-1	11/2009	Environment	ICU mop	CIP-TZP-CAZ-ATM-FEP-IMP-MEM	No	Yes	No	No	Yes	No	Yes
J059	12/2009	Environment	ICU mop	CIP-CN-TZP-CAZ-ATM-AK-IMP-MEM	No	No	No	No	No	No	Yes
J081-1	12/2009	Environment	Squeezer	TZP-ATM-IMP-MEM	Yes	Yes	Yes	No	No	No	No
J081-3	12/2009	Environment	Water	CN-TZP-ATM-IMP-MEM	No	No	No	No	No	No	Yes
J096	12/2009	Environment	Sink	CN-TZP-CAZ-ATM-IMP-MEM	No	Yes	Yes	No	No	No	Yes
J851	12/2009	Environment	Sink	CIP-CN-TZP-CAZ-ATM-FEP-AK-IMP-MEM	No	Yes	No	No	Yes	No	Yes (aadAB)
J327	12/2009	Environment	Sink	CIP-CN-TZP-CAZ-ATM-FEP-AK-IMP-MEM	Yes	No	Yes	No	No	No	Yes
R017	02/2010	Environment	Sink	ATM-FEP-IMP-MEM	No	Yes	No	Yes	No	No	Yes
R007	02/2010	Environment	Wet floor	CIP-TZP-IMP-MEM	Yes	No	No	Yes	No	No	No
S6	02/2010	Environment	Wet floor	CIP-CN-TZP-CAZ-ATM-FEP-AK-IMP-MEM	No	No	No	No	No	Yes	No
S17	02/2010	Environment	Squeezer	ATM-AK-IMP-MEM	No	Yes	Yes	No	No	No	Yes
S10	02/2010	Environment	Wet floor	CIP-IMP	No	No	No	No	Yes	No	No
1942	02/2010	Environment	Sink	CIP-TZP-ATM-AK-FEP-IMP-MEM	Yes	No	No	Yes	No	No	Yes

Laboratory surveillance of 869 clinical specimens (blood, pus, tracheal aspirates, cerebral spinal fluid, sputum, ear swabs and urine catheter from hospitalized patients) for carbapenem resistant Pseudomonas aeruginosa and Acinetobacter species at Mulago National Referral Hospital in Kampala, 2008–2009. For comparison, 80 samples (water, disinfectants, sink-, mop, wet-floor- and squeezer swabs) from the hospital environment were studied
AK, amikacin; CN, gentamicin; IMP, imipenem; MEM, meropenem; CAZ, ceftazidime; FEP, cefepime; ATM, aztreonam; TZP, piperacillin/tazobactam; CIP, ciprofloxacin; Yes, positive; No, negative; MHT, modified Hodge test; IMP-EDTA, imipenem-EDTA double-disk synergy test
^aOnly bla _VIM1-like and bla _IMP1-like genes were detected

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