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Table 4 Propofol effects on liver mitochondrial respiratory chain activities after the 20 h infusion in the 3 groups

From: In vivo study of hepatic oxidative stress and mitochondrial function in rabbits with severe hypotension after propofol prolonged infusion

Activity Group Statistical test p
Saline SMOFlipid Propofol Lipuro
Complex I 4.43 ± 2.33 4.08 ± 0.98 3.60 ± 1.54 F(2,17) = 0.35 0.71
Complex I–III 13.63 ± 5.76 14.44 ± 2.29 13.07 ± 4.32 F(2,17) = 0.15 0.86
Complex II 0.19 ± 0.11 0.14 ± 0.08 0.25 ± 0.11 F(2,17) = 0.68 0.52
Complex II–III 5.01 ± 2.33 4.14 ± 1.54 4.54 ± 1.96 χ2(2) = 0.13 0.94
Complex III 2.11 ± 1.64 2.06 ± 0.57 1.68 ± 0.71 χ2(2) = 0.72 0.69
Complex IV 14.81 ± 9.48 16.34 ± 7.56 10.25 ± 7.79 χ2(2) = 5.54 0.06
Citrate synthase 2.26 ± 1.09 1.56 ± 0.34 2.10 ± 0.63 F(2,17) = 1.43 0.27
  1. Results expressed by M ± SD (mean ± standard deviation) or median and interquartile range for liver mitochondria (10 μg of protein) obtained from different mitochondrial preparations for each experimental group. No statistical significance was observed between groups