In vivo study of hepatic oxidative stress and mitochondrial function in rabbits with severe hypotension after propofol prolonged infusion

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Table 4 Propofol effects on liver mitochondrial respiratory chain activities after the 20 h infusion in the 3 groups

Activity	Group			Statistical test	p
Activity	Saline	SMOFlipid	Propofol Lipuro	Statistical test	p
Complex I	4.43 ± 2.33	4.08 ± 0.98	3.60 ± 1.54	F(2,17) = 0.35	0.71
Complex I–III	13.63 ± 5.76	14.44 ± 2.29	13.07 ± 4.32	F(2,17) = 0.15	0.86
Complex II	0.19 ± 0.11	0.14 ± 0.08	0.25 ± 0.11	F(2,17) = 0.68	0.52
Complex II–III	5.01 ± 2.33	4.14 ± 1.54	4.54 ± 1.96	χ²(2) = 0.13	0.94
Complex III	2.11 ± 1.64	2.06 ± 0.57	1.68 ± 0.71	χ²(2) = 0.72	0.69
Complex IV	14.81 ± 9.48	16.34 ± 7.56	10.25 ± 7.79	χ²(2) = 5.54	0.06
Citrate synthase	2.26 ± 1.09	1.56 ± 0.34	2.10 ± 0.63	F(2,17) = 1.43	0.27

Results expressed by M ± SD (mean ± standard deviation) or median and interquartile range for liver mitochondria (10 μg of protein) obtained from different mitochondrial preparations for each experimental group. No statistical significance was observed between groups